FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283367319> ?p ?o ?g. }

• W4283367319 endingPage "2395" @default.
• W4283367319 startingPage "2383" @default.
• W4283367319 abstract "Given the low survival rate in pancreatic cancer, new therapeutic techniques have been explored, especially for unresectable or borderline resectable disease. Endoscopic ultrasound (EUS) provides real-time imaging and minimally invasive access for local and targeted injection of anti-tumor agents directly into the pancreatic tumor. Limited studies have been reported using this technique for the treatment of pancreatic ductal adenocarcinoma (PDAC).To evaluate the progress made with EUS-guided injectable therapies in the treatment of PDAC.All original articles published in English until July 15, 2021, were retrieved via a library-assisted literature search from Ovid Evidence-Based Medicine Reviews and Scopus databases. Reference lists were reviewed to identify additional relevant articles. Prospective clinical studies evaluating the use of EUS-guided injectable therapies in PDAC were included. Studies primarily directed at non-EUS injectable therapies and other malignancies were excluded. Retrieved manuscripts were reviewed descriptively with on critical appraisal of published studies based on their methods and outcome measures such as safety, feasibility, and effectiveness in terms of tumor response and survival. Heterogeneity in data outcomes and therapeutic techniques limited the ability to perform comparative statistical analysis.A total of thirteen articles (503 patients) were found eligible for inclusion. The EUS-injectable therapies used were heterogeneous among the studies consisting of immunotherapy (n = 5) in 59 patients, chemotherapy (n = 1) in 36 patients, and viral and other biological therapies (n = 7) in 408 patients. Eleven of the studies reviewed were single armed while two were double armed with one randomized trial and one non-randomized comparative study. Overall, the included studies demonstrated EUS-guided injectable therapies to be safe and feasible with different agents as monotherapy or in conjunction with other modalities. Promising results were also observed regarding their efficacy and survival parameters in patients with PDAC.EUS-guided injectable therapies, including immunotherapy, chemotherapy, and viral or other biological therapies have shown minimal adverse events and potential efficacy in the treatment of PDAC. Comparative studies, including controlled trials, are required to confirm these results in order to offer novel EUS-based treatment options for patients with PDAC." @default.
• W4283367319 created "2022-06-25" @default.
• W4283367319 creator A5021679077 @default.
• W4283367319 creator A5026000668 @default.
• W4283367319 creator A5084018434 @default.
• W4283367319 date "2022-06-07" @default.
• W4283367319 modified "2023-09-26" @default.
• W4283367319 title "Endoscopic ultrasound-guided injectable therapy for pancreatic cancer: A systematic review" @default.
• W4283367319 cites W1931508686 @default.
• W4283367319 cites W1970495146 @default.
• W4283367319 cites W1991274670 @default.
• W4283367319 cites W1993147359 @default.
• W4283367319 cites W2002737574 @default.
• W4283367319 cites W2012055729 @default.
• W4283367319 cites W2017576006 @default.
• W4283367319 cites W2019296882 @default.
• W4283367319 cites W2020085359 @default.
• W4283367319 cites W2024888738 @default.
• W4283367319 cites W2033419482 @default.
• W4283367319 cites W2033859126 @default.
• W4283367319 cites W2037580616 @default.
• W4283367319 cites W2044835625 @default.
• W4283367319 cites W2049728014 @default.
• W4283367319 cites W2051217085 @default.
• W4283367319 cites W2066502841 @default.
• W4283367319 cites W2074950810 @default.
• W4283367319 cites W2079790394 @default.
• W4283367319 cites W2080623087 @default.
• W4283367319 cites W2098263349 @default.
• W4283367319 cites W2115791536 @default.
• W4283367319 cites W2128562119 @default.
• W4283367319 cites W2130158346 @default.
• W4283367319 cites W2131070390 @default.
• W4283367319 cites W2135840544 @default.
• W4283367319 cites W2144624167 @default.
• W4283367319 cites W2151985879 @default.
• W4283367319 cites W2167739507 @default.
• W4283367319 cites W2193354702 @default.
• W4283367319 cites W2305010449 @default.
• W4283367319 cites W2467204365 @default.
• W4283367319 cites W2483295712 @default.
• W4283367319 cites W2550899530 @default.
• W4283367319 cites W2561499686 @default.
• W4283367319 cites W2767852470 @default.
• W4283367319 cites W2774349351 @default.
• W4283367319 cites W2807544832 @default.
• W4283367319 cites W2909997346 @default.
• W4283367319 cites W2941269974 @default.
• W4283367319 cites W2947666181 @default.
• W4283367319 cites W2969029625 @default.
• W4283367319 cites W3008157420 @default.
• W4283367319 cites W3010042238 @default.
• W4283367319 cites W3088352982 @default.
• W4283367319 cites W3112325957 @default.
• W4283367319 cites W3119005666 @default.
• W4283367319 cites W4251939478 @default.
• W4283367319 cites W4376453765 @default.
• W4283367319 doi "https://doi.org/10.3748/wjg.v28.i21.2383" @default.
• W4283367319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35800184" @default.
• W4283367319 hasPublicationYear "2022" @default.
• W4283367319 type Work @default.
• W4283367319 citedByCount "2" @default.
• W4283367319 countsByYear W42833673192023 @default.
• W4283367319 crossrefType "journal-article" @default.
• W4283367319 hasAuthorship W4283367319A5021679077 @default.
• W4283367319 hasAuthorship W4283367319A5026000668 @default.
• W4283367319 hasAuthorship W4283367319A5084018434 @default.
• W4283367319 hasBestOaLocation W42833673191 @default.
• W4283367319 hasConcept C121608353 @default.
• W4283367319 hasConcept C126322002 @default.
• W4283367319 hasConcept C126838900 @default.
• W4283367319 hasConcept C143998085 @default.
• W4283367319 hasConcept C168563851 @default.
• W4283367319 hasConcept C2780210213 @default.
• W4283367319 hasConcept C2780390042 @default.
• W4283367319 hasConcept C535046627 @default.
• W4283367319 hasConcept C71924100 @default.
• W4283367319 hasConceptScore W4283367319C121608353 @default.
• W4283367319 hasConceptScore W4283367319C126322002 @default.
• W4283367319 hasConceptScore W4283367319C126838900 @default.
• W4283367319 hasConceptScore W4283367319C143998085 @default.
• W4283367319 hasConceptScore W4283367319C168563851 @default.
• W4283367319 hasConceptScore W4283367319C2780210213 @default.
• W4283367319 hasConceptScore W4283367319C2780390042 @default.
• W4283367319 hasConceptScore W4283367319C535046627 @default.
• W4283367319 hasConceptScore W4283367319C71924100 @default.
• W4283367319 hasIssue "21" @default.
• W4283367319 hasLocation W42833673191 @default.
• W4283367319 hasLocation W42833673192 @default.
• W4283367319 hasLocation W42833673193 @default.
• W4283367319 hasOpenAccess W4283367319 @default.
• W4283367319 hasPrimaryLocation W42833673191 @default.
• W4283367319 hasRelatedWork W1936092177 @default.
• W4283367319 hasRelatedWork W2020938755 @default.
• W4283367319 hasRelatedWork W2082612687 @default.
• W4283367319 hasRelatedWork W2108137221 @default.
• W4283367319 hasRelatedWork W2963585294 @default.
• W4283367319 hasRelatedWork W2965490941 @default.

• next