FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283393048> ?p ?o ?g. }

• W4283393048 endingPage "1437" @default.
• W4283393048 startingPage "1432" @default.
• W4283393048 abstract "Neurofilament light chain (NfL) levels in cerebrospinal fluid and serum are reliable indicators for neuroaxonal damage in a broad spectrum of neurodegenerative diseases. Herein, we investigate NfL levels in serum and anterior chamber fluid of patients with glaucoma.Patients scheduled for routine glaucoma or cataract surgery were recruited for this study. Retinal nerve fibre layer thickness was measured by optical coherence tomography (OCT, Heidelberg Spectralis). NfL levels in serum and in anterior chamber fluid were analysed with Simoa SR-X Analyzer (Quanterix; NFLIGHT, Lexington, Massachusetts, USA). T-test was used for parametric data and Mann-Whitney-U test for nonparametric data. Spearman's rank-order correlation was used to investigate correlations. P values<0.05 were considered as statistically significant.Sixty patients with glaucoma and 58 controls were enrolled. Serum NfL concentration of patients with glaucoma was similar to serum NfL concentration in controls (median (IQR); 22.7 (18.9) pg/mL vs 22.5 (24.0) pg/mL; p=0.763). A positive correlation of serum NfL with age was observed in both patients with glaucoma (r=0.77; p<0.001) and in the control group (r=0.82, p<0.001). In the anterior chamber fluid, the NfL concentration was substantially increased in patients with glaucoma compared with controls (20.7 (101.3) pg/mL vs 3.1 (2.9) pg/mL; p<0.001). Furthermore, we found a positive correlation of anterior chamber fluid NfL with preoperative intraocular pressure (r=0.39, p=0.003) and with retinal nerve fibre layer thickness (r=0.58, p<0.001).NfL levels in anterior chamber fluid are elevated in patients with glaucoma and correlate with intraocular pressure and retinal nerve fibre layer thickness. The presented data strongly support anterior chamber fluid NfL as a new marker for glaucoma." @default.
• W4283393048 created "2022-06-25" @default.
• W4283393048 creator A5007855613 @default.
• W4283393048 creator A5009788892 @default.
• W4283393048 creator A5013325021 @default.
• W4283393048 creator A5015017045 @default.
• W4283393048 creator A5019656577 @default.
• W4283393048 creator A5019678268 @default.
• W4283393048 creator A5027413439 @default.
• W4283393048 creator A5036897215 @default.
• W4283393048 creator A5038841833 @default.
• W4283393048 creator A5063907074 @default.
• W4283393048 creator A5065750087 @default.
• W4283393048 creator A5076936282 @default.
• W4283393048 creator A5081767430 @default.
• W4283393048 creator A5090354446 @default.
• W4283393048 date "2022-06-24" @default.
• W4283393048 modified "2023-10-17" @default.
• W4283393048 title "Neurofilament light chain: a new marker for neuronal decay in the anterior chamber fluid of patients with glaucoma" @default.
• W4283393048 cites W1516093328 @default.
• W4283393048 cites W1963948646 @default.
• W4283393048 cites W1974134074 @default.
• W4283393048 cites W2001318290 @default.
• W4283393048 cites W2004011839 @default.
• W4283393048 cites W2026863482 @default.
• W4283393048 cites W2034742711 @default.
• W4283393048 cites W2058812152 @default.
• W4283393048 cites W2070894477 @default.
• W4283393048 cites W2077419439 @default.
• W4283393048 cites W2092198587 @default.
• W4283393048 cites W2093889402 @default.
• W4283393048 cites W2106529000 @default.
• W4283393048 cites W2140594570 @default.
• W4283393048 cites W2148890166 @default.
• W4283393048 cites W2160605010 @default.
• W4283393048 cites W2511801769 @default.
• W4283393048 cites W2557439420 @default.
• W4283393048 cites W2627019718 @default.
• W4283393048 cites W2889223700 @default.
• W4283393048 cites W2900526440 @default.
• W4283393048 cites W2901812979 @default.
• W4283393048 cites W2905353061 @default.
• W4283393048 cites W2914396477 @default.
• W4283393048 cites W2950228559 @default.
• W4283393048 cites W2969791528 @default.
• W4283393048 cites W2979400575 @default.
• W4283393048 cites W2988385847 @default.
• W4283393048 cites W3000594120 @default.
• W4283393048 cites W3004767455 @default.
• W4283393048 cites W3087460625 @default.
• W4283393048 cites W3170817209 @default.
• W4283393048 cites W3187555740 @default.
• W4283393048 cites W3214113275 @default.
• W4283393048 doi "https://doi.org/10.1136/bjo-2021-320828" @default.
• W4283393048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35750478" @default.
• W4283393048 hasPublicationYear "2022" @default.
• W4283393048 type Work @default.
• W4283393048 citedByCount "3" @default.
• W4283393048 countsByYear W42833930482022 @default.
• W4283393048 countsByYear W42833930482023 @default.
• W4283393048 crossrefType "journal-article" @default.
• W4283393048 hasAuthorship W4283393048A5007855613 @default.
• W4283393048 hasAuthorship W4283393048A5009788892 @default.
• W4283393048 hasAuthorship W4283393048A5013325021 @default.
• W4283393048 hasAuthorship W4283393048A5015017045 @default.
• W4283393048 hasAuthorship W4283393048A5019656577 @default.
• W4283393048 hasAuthorship W4283393048A5019678268 @default.
• W4283393048 hasAuthorship W4283393048A5027413439 @default.
• W4283393048 hasAuthorship W4283393048A5036897215 @default.
• W4283393048 hasAuthorship W4283393048A5038841833 @default.
• W4283393048 hasAuthorship W4283393048A5063907074 @default.
• W4283393048 hasAuthorship W4283393048A5065750087 @default.
• W4283393048 hasAuthorship W4283393048A5076936282 @default.
• W4283393048 hasAuthorship W4283393048A5081767430 @default.
• W4283393048 hasAuthorship W4283393048A5090354446 @default.
• W4283393048 hasConcept C118487528 @default.
• W4283393048 hasConcept C126322002 @default.
• W4283393048 hasConcept C12868164 @default.
• W4283393048 hasConcept C2778527774 @default.
• W4283393048 hasConcept C2779651940 @default.
• W4283393048 hasConcept C2781092963 @default.
• W4283393048 hasConcept C71924100 @default.
• W4283393048 hasConceptScore W4283393048C118487528 @default.
• W4283393048 hasConceptScore W4283393048C126322002 @default.
• W4283393048 hasConceptScore W4283393048C12868164 @default.
• W4283393048 hasConceptScore W4283393048C2778527774 @default.
• W4283393048 hasConceptScore W4283393048C2779651940 @default.
• W4283393048 hasConceptScore W4283393048C2781092963 @default.
• W4283393048 hasConceptScore W4283393048C71924100 @default.
• W4283393048 hasIssue "10" @default.
• W4283393048 hasLocation W42833930481 @default.
• W4283393048 hasLocation W42833930482 @default.
• W4283393048 hasOpenAccess W4283393048 @default.
• W4283393048 hasPrimaryLocation W42833930481 @default.
• W4283393048 hasRelatedWork W1971004186 @default.
• W4283393048 hasRelatedWork W1980935057 @default.
• W4283393048 hasRelatedWork W2032704621 @default.
• W4283393048 hasRelatedWork W2042967592 @default.

• next