Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283395367> ?p ?o ?g. }
- W4283395367 endingPage "1302" @default.
- W4283395367 startingPage "1293" @default.
- W4283395367 abstract "The first COVID-19 vaccine outside a clinical trial setting was administered on Dec 8, 2020. To ensure global vaccine equity, vaccine targets were set by the COVID-19 Vaccines Global Access (COVAX) Facility and WHO. However, due to vaccine shortfalls, these targets were not achieved by the end of 2021. We aimed to quantify the global impact of the first year of COVID-19 vaccination programmes.A mathematical model of COVID-19 transmission and vaccination was separately fit to reported COVID-19 mortality and all-cause excess mortality in 185 countries and territories. The impact of COVID-19 vaccination programmes was determined by estimating the additional lives lost if no vaccines had been distributed. We also estimated the additional deaths that would have been averted had the vaccination coverage targets of 20% set by COVAX and 40% set by WHO been achieved by the end of 2021.Based on official reported COVID-19 deaths, we estimated that vaccinations prevented 14·4 million (95% credible interval [Crl] 13·7-15·9) deaths from COVID-19 in 185 countries and territories between Dec 8, 2020, and Dec 8, 2021. This estimate rose to 19·8 million (95% Crl 19·1-20·4) deaths from COVID-19 averted when we used excess deaths as an estimate of the true extent of the pandemic, representing a global reduction of 63% in total deaths (19·8 million of 31·4 million) during the first year of COVID-19 vaccination. In COVAX Advance Market Commitment countries, we estimated that 41% of excess mortality (7·4 million [95% Crl 6·8-7·7] of 17·9 million deaths) was averted. In low-income countries, we estimated that an additional 45% (95% CrI 42-49) of deaths could have been averted had the 20% vaccination coverage target set by COVAX been met by each country, and that an additional 111% (105-118) of deaths could have been averted had the 40% target set by WHO been met by each country by the end of 2021.COVID-19 vaccination has substantially altered the course of the pandemic, saving tens of millions of lives globally. However, inadequate access to vaccines in low-income countries has limited the impact in these settings, reinforcing the need for global vaccine equity and coverage.Schmidt Science Fellowship in partnership with the Rhodes Trust; WHO; UK Medical Research Council; Gavi, the Vaccine Alliance; Bill & Melinda Gates Foundation; National Institute for Health Research; and Community Jameel." @default.
- W4283395367 created "2022-06-25" @default.
- W4283395367 creator A5033136483 @default.
- W4283395367 creator A5047646297 @default.
- W4283395367 creator A5059457858 @default.
- W4283395367 creator A5071354925 @default.
- W4283395367 creator A5080897367 @default.
- W4283395367 creator A5088724399 @default.
- W4283395367 date "2022-09-01" @default.
- W4283395367 modified "2023-10-11" @default.
- W4283395367 title "Global impact of the first year of COVID-19 vaccination: a mathematical modelling study" @default.
- W4283395367 cites W3035706118 @default.
- W4283395367 cites W3123481858 @default.
- W4283395367 cites W3131672727 @default.
- W4283395367 cites W3134208712 @default.
- W4283395367 cites W3136554439 @default.
- W4283395367 cites W3148920007 @default.
- W4283395367 cites W3156138520 @default.
- W4283395367 cites W3173464765 @default.
- W4283395367 cites W3178079110 @default.
- W4283395367 cites W3185452484 @default.
- W4283395367 cites W3205588626 @default.
- W4283395367 cites W3206679903 @default.
- W4283395367 cites W3216532396 @default.
- W4283395367 cites W4205810842 @default.
- W4283395367 cites W4220883857 @default.
- W4283395367 cites W4225750634 @default.
- W4283395367 cites W4226181138 @default.
- W4283395367 cites W4281556556 @default.
- W4283395367 doi "https://doi.org/10.1016/s1473-3099(22)00320-6" @default.
- W4283395367 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35753318" @default.
- W4283395367 hasPublicationYear "2022" @default.
- W4283395367 type Work @default.
- W4283395367 citedByCount "526" @default.
- W4283395367 countsByYear W42833953672021 @default.
- W4283395367 countsByYear W42833953672022 @default.
- W4283395367 countsByYear W42833953672023 @default.
- W4283395367 crossrefType "journal-article" @default.
- W4283395367 hasAuthorship W4283395367A5033136483 @default.
- W4283395367 hasAuthorship W4283395367A5047646297 @default.
- W4283395367 hasAuthorship W4283395367A5059457858 @default.
- W4283395367 hasAuthorship W4283395367A5071354925 @default.
- W4283395367 hasAuthorship W4283395367A5080897367 @default.
- W4283395367 hasAuthorship W4283395367A5088724399 @default.
- W4283395367 hasBestOaLocation W42833953671 @default.
- W4283395367 hasConcept C119599485 @default.
- W4283395367 hasConcept C127413603 @default.
- W4283395367 hasConcept C138816342 @default.
- W4283395367 hasConcept C142724271 @default.
- W4283395367 hasConcept C144024400 @default.
- W4283395367 hasConcept C149923435 @default.
- W4283395367 hasConcept C159047783 @default.
- W4283395367 hasConcept C159110408 @default.
- W4283395367 hasConcept C22070199 @default.
- W4283395367 hasConcept C2779134260 @default.
- W4283395367 hasConcept C3007834351 @default.
- W4283395367 hasConcept C3008058167 @default.
- W4283395367 hasConcept C46578552 @default.
- W4283395367 hasConcept C524204448 @default.
- W4283395367 hasConcept C71924100 @default.
- W4283395367 hasConcept C761482 @default.
- W4283395367 hasConcept C89623803 @default.
- W4283395367 hasConcept C99454951 @default.
- W4283395367 hasConceptScore W4283395367C119599485 @default.
- W4283395367 hasConceptScore W4283395367C127413603 @default.
- W4283395367 hasConceptScore W4283395367C138816342 @default.
- W4283395367 hasConceptScore W4283395367C142724271 @default.
- W4283395367 hasConceptScore W4283395367C144024400 @default.
- W4283395367 hasConceptScore W4283395367C149923435 @default.
- W4283395367 hasConceptScore W4283395367C159047783 @default.
- W4283395367 hasConceptScore W4283395367C159110408 @default.
- W4283395367 hasConceptScore W4283395367C22070199 @default.
- W4283395367 hasConceptScore W4283395367C2779134260 @default.
- W4283395367 hasConceptScore W4283395367C3007834351 @default.
- W4283395367 hasConceptScore W4283395367C3008058167 @default.
- W4283395367 hasConceptScore W4283395367C46578552 @default.
- W4283395367 hasConceptScore W4283395367C524204448 @default.
- W4283395367 hasConceptScore W4283395367C71924100 @default.
- W4283395367 hasConceptScore W4283395367C761482 @default.
- W4283395367 hasConceptScore W4283395367C89623803 @default.
- W4283395367 hasConceptScore W4283395367C99454951 @default.
- W4283395367 hasIssue "9" @default.
- W4283395367 hasLocation W42833953671 @default.
- W4283395367 hasLocation W42833953672 @default.
- W4283395367 hasLocation W42833953673 @default.
- W4283395367 hasLocation W42833953674 @default.
- W4283395367 hasLocation W42833953675 @default.
- W4283395367 hasOpenAccess W4283395367 @default.
- W4283395367 hasPrimaryLocation W42833953671 @default.
- W4283395367 hasRelatedWork W3017171836 @default.
- W4283395367 hasRelatedWork W3025176011 @default.
- W4283395367 hasRelatedWork W3027835066 @default.
- W4283395367 hasRelatedWork W3032320397 @default.
- W4283395367 hasRelatedWork W3033635008 @default.
- W4283395367 hasRelatedWork W3119540162 @default.
- W4283395367 hasRelatedWork W3152606407 @default.
- W4283395367 hasRelatedWork W4280491013 @default.
- W4283395367 hasRelatedWork W4308017287 @default.