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• W4283397379 abstract "Obesity is the epidemic of our era and its incidence is supposed to increase by more than 30% by 2030. It is commonly defined as a chronic and metabolic disease with an excessive accumulation of body fat in relation to fat-free mass, both in terms of quantity and distribution at specific points on the body. The effects of obesity have an important impact on different clinical areas, particularly endocrinology, cardiology, and nephrology. Indeed, increased rates of obesity have been associated with increased risk of cardiovascular disease (CVD), cancer, type 2 diabetes (T2D), dyslipidemia, hypertension, renal diseases, and neurocognitive impairment. Obesity-related chronic kidney disease (CKD) has been ascribed to intrarenal fat accumulation along the proximal tubule, glomeruli, renal sinus, and around the kidney capsule, and to hemodynamic changes with hyperfiltration, albuminuria, and impaired glomerular filtration rate. In addition, hypertension, dyslipidemia, and diabetes, which arise as a consequence of overweight, contribute to amplifying renal dysfunction in both the native and transplanted kidney. Overall, several mechanisms are closely related to the onset and progression of CKD in the general population, including changes in renal hemodynamics, neurohumoral pathways, renal adiposity, local and systemic inflammation, dysbiosis of microbiota, insulin resistance, and fibrotic process. Unfortunately, there are no clinical practice guidelines for the management of patients with obesity-related CKD. Therefore, dietary management is based on the clinical practice guidelines for the nutritional care of adults with CKD, developed and published by the National Kidney Foundation, Kidney Disease Outcome Quality Initiative and common recommendations for the healthy population. Optimal nutritional management of these patients should follow the guidelines of the Mediterranean diet, which is known to be associated with a lower incidence of CVD and beneficial effects on chronic diseases such as diabetes, obesity, and cognitive health. Mediterranean-style diets are often unsuccessful in promoting efficient weight loss, especially in patients with altered glucose metabolism. For this purpose, this review also discusses the use of non-classical weight loss approaches in CKD, including intermittent fasting and ketogenic diet to contrast the onset and progression of obesity-related CKD." @default.
• W4283397379 created "2022-06-25" @default.
• W4283397379 creator A5000972068 @default.
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• W4283397379 creator A5091403457 @default.
• W4283397379 date "2022-06-24" @default.
• W4283397379 modified "2023-10-14" @default.
• W4283397379 title "Obesity-Related Chronic Kidney Disease: Principal Mechanisms and New Approaches in Nutritional Management" @default.
• W4283397379 cites W1499133231 @default.
• W4283397379 cites W1608447958 @default.
• W4283397379 cites W171809087 @default.
• W4283397379 cites W1926710994 @default.
• W4283397379 cites W1965318881 @default.
• W4283397379 cites W1966289658 @default.
• W4283397379 cites W1968326337 @default.
• W4283397379 cites W1971415551 @default.
• W4283397379 cites W1977328678 @default.
• W4283397379 cites W1978318376 @default.
• W4283397379 cites W1986834239 @default.
• W4283397379 cites W1988130273 @default.
• W4283397379 cites W1990324289 @default.
• W4283397379 cites W2007887780 @default.
• W4283397379 cites W2015180162 @default.
• W4283397379 cites W2016539998 @default.
• W4283397379 cites W2018834773 @default.
• W4283397379 cites W2019423369 @default.
• W4283397379 cites W2031769985 @default.
• W4283397379 cites W2032230795 @default.
• W4283397379 cites W2033739825 @default.
• W4283397379 cites W2035812981 @default.
• W4283397379 cites W2037251283 @default.
• W4283397379 cites W2041136224 @default.
• W4283397379 cites W2046922993 @default.
• W4283397379 cites W2064022883 @default.
• W4283397379 cites W2068988287 @default.
• W4283397379 cites W2070447089 @default.
• W4283397379 cites W2072317734 @default.
• W4283397379 cites W2077015438 @default.
• W4283397379 cites W2077553363 @default.
• W4283397379 cites W2078378773 @default.
• W4283397379 cites W2083705842 @default.
• W4283397379 cites W2084793748 @default.
• W4283397379 cites W2093061174 @default.
• W4283397379 cites W2095390658 @default.
• W4283397379 cites W2103015797 @default.
• W4283397379 cites W2104448316 @default.
• W4283397379 cites W2104890139 @default.
• W4283397379 cites W2107616906 @default.
• W4283397379 cites W2113882071 @default.
• W4283397379 cites W2115225456 @default.
• W4283397379 cites W2117555254 @default.
• W4283397379 cites W2118493857 @default.
• W4283397379 cites W2122398419 @default.
• W4283397379 cites W2125826054 @default.
• W4283397379 cites W2129917444 @default.
• W4283397379 cites W2130492862 @default.
• W4283397379 cites W2135019055 @default.
• W4283397379 cites W2139261508 @default.
• W4283397379 cites W2139716027 @default.
• W4283397379 cites W2141819737 @default.
• W4283397379 cites W2145303552 @default.
• W4283397379 cites W2149573313 @default.
• W4283397379 cites W2156150528 @default.
• W4283397379 cites W2163169997 @default.
• W4283397379 cites W2167062509 @default.
• W4283397379 cites W2174278940 @default.
• W4283397379 cites W2239670076 @default.
• W4283397379 cites W2277103284 @default.
• W4283397379 cites W2321007701 @default.
• W4283397379 cites W2333388731 @default.
• W4283397379 cites W2415080161 @default.
• W4283397379 cites W2416826834 @default.
• W4283397379 cites W2475239215 @default.
• W4283397379 cites W2492525689 @default.
• W4283397379 cites W2513791609 @default.
• W4283397379 cites W2513831181 @default.
• W4283397379 cites W2516647861 @default.
• W4283397379 cites W2518536384 @default.
• W4283397379 cites W2550330342 @default.
• W4283397379 cites W2573524518 @default.
• W4283397379 cites W2582613914 @default.
• W4283397379 cites W2584401577 @default.
• W4283397379 cites W2587125180 @default.
• W4283397379 cites W2607222912 @default.
• W4283397379 cites W2621182090 @default.
• W4283397379 cites W2737733846 @default.
• W4283397379 cites W2740167666 @default.
• W4283397379 cites W2744344423 @default.
• W4283397379 cites W2791363836 @default.
• W4283397379 cites W2801863764 @default.
• W4283397379 cites W2804629684 @default.
• W4283397379 cites W2805160465 @default.
• W4283397379 cites W2909668868 @default.
• W4283397379 cites W2924743030 @default.
• W4283397379 cites W2929633637 @default.

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