Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283399805> ?p ?o ?g. }
- W4283399805 abstract "Tremor is one of the core symptoms of Parkinson's disease (PD), but its mechanism is poorly understood. The cerebellum is a growing focus in PD-related researches and is reported to play an important role in tremor in PD. The cerebellum may participate in the modulation of tremor amplitude via cerebello-thalamo-cortical circuits. The cerebellar excitatory projections to the ventral intermediate nucleus of the thalamus may be enhanced due to PD-related changes, including dopaminergic/non-dopaminergic system abnormality, white matter damage, and deep nuclei impairment, which may contribute to dysregulation and resistance to levodopa of tremor. This review summarized the pathological, structural, and functional changes of the cerebellum in PD and discussed the role of the cerebellum in PD-related tremor, aiming to provide an overview of the cerebellum-related mechanism of tremor in PD." @default.
- W4283399805 created "2022-06-25" @default.
- W4283399805 creator A5000486412 @default.
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- W4283399805 creator A5003115460 @default.
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- W4283399805 creator A5013881064 @default.
- W4283399805 creator A5014123645 @default.
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- W4283399805 creator A5049057154 @default.
- W4283399805 creator A5049115665 @default.
- W4283399805 creator A5060282442 @default.
- W4283399805 creator A5063832468 @default.
- W4283399805 creator A5070492082 @default.
- W4283399805 date "2022-06-24" @default.
- W4283399805 modified "2023-10-14" @default.
- W4283399805 title "A review on pathology, mechanism, and therapy for cerebellum and tremor in Parkinson’s disease" @default.
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