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• W4283455149 endingPage "888" @default.
• W4283455149 startingPage "872" @default.
• W4283455149 abstract "Genome annotations have uncovered the production of at least one transcript from nearly all loci in the genome at some given time throughout the development. Surprisingly, many of these transcripts do not code for proteins and are relatively long in size, thus called long noncoding RNAs (lncRNAs). Next- and third-generation sequencing technologies have amassed numerous lncRNAs expressed under different phenotypic conditions, yet many remain to be functionally characterized. LncRNAs regulate gene expression by functioning as scaffold, decoy, signaling, and guide molecules both at the transcriptional and post-transcriptional levels, interacting with different types of macromolecules, such as proteins, DNA, and RNA. Here, we review the potential regulatory role of lncRNAs in apoptosis and cancer as some of these lncRNAs may have the diagnostic and therapeutic potential in cancer." @default.
• W4283455149 created "2022-06-26" @default.
• W4283455149 creator A5049439869 @default.
• W4283455149 creator A5073206480 @default.
• W4283455149 creator A5079338444 @default.
• W4283455149 date "2023-06-01" @default.
• W4283455149 modified "2023-10-16" @default.
• W4283455149 title "Long Noncoding RNAs in Human Cancer and Apoptosis" @default.
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