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- W4283459608 abstract "α-Fluorinated acrylates could act as Michael acceptors and become a platform toward the synthesis of relevant complex molecules. Very few conjugate additions have been developed in the literature with these specific substrates, and herein, we reported the first phospha-Michael addition (PMA) on α-trifluoromethylacrylates and α-fluoromethylacrylates. The reaction proved to be highly tolerant and gave original products containing contiguous C-P and C-CFY2 (Y = F or H) bonds in good to excellent yields and diastereoselectivities." @default.
- W4283459608 created "2022-06-26" @default.
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- W4283459608 date "2022-06-24" @default.
- W4283459608 modified "2023-10-11" @default.
- W4283459608 title "Phospha-Michael Addition on α-Fluorinated Acrylates: A Straightforward Access to Polyfunctionalized Fine Chemicals" @default.
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- W4283459608 doi "https://doi.org/10.1021/acs.joc.2c00937" @default.
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