Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283462787> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W4283462787 endingPage "102149" @default.
- W4283462787 startingPage "102149" @default.
- W4283462787 abstract "Chiliadenus iphinoides is a Mediterranean basin plant and utilized in traditional medicine in Palestine. Thus, the aim was to investigate, for the first time, antioxidant, antimicrobial and cytotoxic properties of C. iphinoides gathered from Jenin-Palestine. The DPPH technique was used to measure antioxidant activity. Antimicrobial activity was tested employing broth microdilution and agar-well diffusion methods. Anti-proliferative and apoptotic activities were evaluated utilizing colorimetric methods. Aqueous, methanol, acetone and hexane extracts and trolox exhibited antioxidant activities with IC50 values of 5.2, 7.5, 4.2, 218 and 0.8 μg/ml, respectively. Acetone extracts had the most potent and broad spectrum antimicrobial activity followed by hexane and then methanol extracts, while aqueous extracts had no effect except against S. sonnei. Both hexane and acetone extracts had strong anti-proliferative effects followed by methanol extracts. Caspase-3 activity was induced by hexane extract 2 folds, similar to doxorubicin effect, a chemotherapeutic medicine. In the current study we demonstrated that acetone and hexane extracts possessed a strong antiproliferative property compared to methanol extract. Thiswas mediated via apoptosis; suggesting that they represent an attractive source of bioactive anticancer molecules. Acetone, hexane and methanol extracts possess broad spectrum antimicrobial effects. Acetone, aqueous and methanol extracts have strong antioxidant effects. Interestingly, aqueous extract is a potential safe source of antioxidant agents and natural preservatives instead of chemical preservatives in pharmaceutical and food products. However, it is necessary to validate these findings in vivo in the future." @default.
- W4283462787 created "2022-06-26" @default.
- W4283462787 creator A5032277032 @default.
- W4283462787 creator A5073926104 @default.
- W4283462787 creator A5079730448 @default.
- W4283462787 date "2022-09-01" @default.
- W4283462787 modified "2023-10-14" @default.
- W4283462787 title "Antioxidant, antimicrobial and cytotoxic properties of four different extracts derived from the aerial parts of Chiliadenus iphinoides" @default.
- W4283462787 cites W1487878063 @default.
- W4283462787 cites W1507232815 @default.
- W4283462787 cites W1969524738 @default.
- W4283462787 cites W2059246311 @default.
- W4283462787 cites W2083106055 @default.
- W4283462787 cites W2088828773 @default.
- W4283462787 cites W2093055820 @default.
- W4283462787 cites W2094424564 @default.
- W4283462787 cites W2113596478 @default.
- W4283462787 cites W2132963724 @default.
- W4283462787 cites W2268327570 @default.
- W4283462787 cites W2558941103 @default.
- W4283462787 cites W2605350666 @default.
- W4283462787 cites W2790248202 @default.
- W4283462787 cites W2801754983 @default.
- W4283462787 cites W2889588533 @default.
- W4283462787 cites W2899961157 @default.
- W4283462787 cites W2953844286 @default.
- W4283462787 cites W2973682111 @default.
- W4283462787 cites W3094501464 @default.
- W4283462787 cites W3119952098 @default.
- W4283462787 cites W3130954936 @default.
- W4283462787 cites W63281979 @default.
- W4283462787 doi "https://doi.org/10.1016/j.eujim.2022.102149" @default.
- W4283462787 hasPublicationYear "2022" @default.
- W4283462787 type Work @default.
- W4283462787 citedByCount "1" @default.
- W4283462787 countsByYear W42834627872022 @default.
- W4283462787 crossrefType "journal-article" @default.
- W4283462787 hasAuthorship W4283462787A5032277032 @default.
- W4283462787 hasAuthorship W4283462787A5073926104 @default.
- W4283462787 hasAuthorship W4283462787A5079730448 @default.
- W4283462787 hasConcept C178790620 @default.
- W4283462787 hasConcept C185592680 @default.
- W4283462787 hasConcept C2777077568 @default.
- W4283462787 hasConcept C2778004101 @default.
- W4283462787 hasConcept C2779607525 @default.
- W4283462787 hasConcept C2781213060 @default.
- W4283462787 hasConcept C2781401929 @default.
- W4283462787 hasConcept C31903555 @default.
- W4283462787 hasConcept C43617362 @default.
- W4283462787 hasConcept C4937899 @default.
- W4283462787 hasConcept C55493867 @default.
- W4283462787 hasConcept C556039675 @default.
- W4283462787 hasConcept C71924100 @default.
- W4283462787 hasConceptScore W4283462787C178790620 @default.
- W4283462787 hasConceptScore W4283462787C185592680 @default.
- W4283462787 hasConceptScore W4283462787C2777077568 @default.
- W4283462787 hasConceptScore W4283462787C2778004101 @default.
- W4283462787 hasConceptScore W4283462787C2779607525 @default.
- W4283462787 hasConceptScore W4283462787C2781213060 @default.
- W4283462787 hasConceptScore W4283462787C2781401929 @default.
- W4283462787 hasConceptScore W4283462787C31903555 @default.
- W4283462787 hasConceptScore W4283462787C43617362 @default.
- W4283462787 hasConceptScore W4283462787C4937899 @default.
- W4283462787 hasConceptScore W4283462787C55493867 @default.
- W4283462787 hasConceptScore W4283462787C556039675 @default.
- W4283462787 hasConceptScore W4283462787C71924100 @default.
- W4283462787 hasLocation W42834627871 @default.
- W4283462787 hasOpenAccess W4283462787 @default.
- W4283462787 hasPrimaryLocation W42834627871 @default.
- W4283462787 hasRelatedWork W1973614701 @default.
- W4283462787 hasRelatedWork W2079446804 @default.
- W4283462787 hasRelatedWork W2147612173 @default.
- W4283462787 hasRelatedWork W2184783797 @default.
- W4283462787 hasRelatedWork W2391967816 @default.
- W4283462787 hasRelatedWork W2786869502 @default.
- W4283462787 hasRelatedWork W2909174447 @default.
- W4283462787 hasRelatedWork W3194967994 @default.
- W4283462787 hasRelatedWork W36743795 @default.
- W4283462787 hasRelatedWork W4206228078 @default.
- W4283462787 hasVolume "54" @default.
- W4283462787 isParatext "false" @default.
- W4283462787 isRetracted "false" @default.
- W4283462787 workType "article" @default.