FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283514077> ?p ?o ?g. }

• W4283514077 endingPage "372" @default.
• W4283514077 startingPage "363" @default.
• W4283514077 abstract "Background: Neonatal congenital hypothyroidism screening is performed by measuring thyroid-stimulating hormone (TSH) in a dried blood spot (DBS) sample, whereas acquired hypothyroidism uses serum TSH. There is no established DBS TSH reference interval, but knowing this is useful, as some patients cannot tolerate venepuncture, so DBS collection is seen as an acceptable alternative. The aim of this study was to establish DBS TSH reference intervals in adults and neonates (day 5-8), and determine the relationship between serum and DBS TSH.Methods: Euthyroid adults, not on thyroid medication and with a normal haematocrit, were selected. If they had a paired lithium heparin sample, DBS were prepared by spotting 50 µL of whole blood onto filter paper. Dried blood spot TSH was measured using the PerkinElmer Neonatal hTSH kit on the GSP instrument and serum using the Abbott Architect assay. The relationship between DBS and serum TSH was analysed using Passing-Bablok regression and the adult DBS TSH reference interval calculated using transformed data. The neonatal reference interval was calculated from screening results using the non-parametric method.Results: Overall, 109 adult samples were included in the study (61 female). The Passing-Bablok regression was: DBS TSH = 0.68 × serum TSH + 0.07, and reference interval was 0.49-3.07 mU/L. The neonatal DBS reference interval was 0.40-4.10 mU/L from 8351 results.Conclusion: This study derived adult and neonate TSH DBS reference intervals using the GSP analyser and established the relationship between serum and DBS TSH. Knowing this information will allow for improved interpretation of DBS TSH results." @default.
• W4283514077 created "2022-06-27" @default.
• W4283514077 creator A5008510766 @default.
• W4283514077 creator A5023552643 @default.
• W4283514077 creator A5043344669 @default.
• W4283514077 creator A5054911654 @default.
• W4283514077 creator A5062070780 @default.
• W4283514077 creator A5081900456 @default.
• W4283514077 date "2022-07-05" @default.
• W4283514077 modified "2023-09-27" @default.
• W4283514077 title "Adult and neonate TSH blood spot reference intervals" @default.
• W4283514077 cites W1626598231 @default.
• W4283514077 cites W1975793547 @default.
• W4283514077 cites W1998924145 @default.
• W4283514077 cites W2005736865 @default.
• W4283514077 cites W2020249822 @default.
• W4283514077 cites W2094003527 @default.
• W4283514077 cites W2104577649 @default.
• W4283514077 cites W2108478002 @default.
• W4283514077 cites W2118758311 @default.
• W4283514077 cites W2192098819 @default.
• W4283514077 cites W2243808066 @default.
• W4283514077 cites W2345078908 @default.
• W4283514077 cites W2528672416 @default.
• W4283514077 cites W2782759999 @default.
• W4283514077 cites W2801252768 @default.
• W4283514077 cites W2887516490 @default.
• W4283514077 cites W2994741823 @default.
• W4283514077 cites W3206948482 @default.
• W4283514077 cites W4211152088 @default.
• W4283514077 doi "https://doi.org/10.1177/00045632221112654" @default.
• W4283514077 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35751155" @default.
• W4283514077 hasPublicationYear "2022" @default.
• W4283514077 type Work @default.
• W4283514077 citedByCount "0" @default.
• W4283514077 crossrefType "journal-article" @default.
• W4283514077 hasAuthorship W4283514077A5008510766 @default.
• W4283514077 hasAuthorship W4283514077A5023552643 @default.
• W4283514077 hasAuthorship W4283514077A5043344669 @default.
• W4283514077 hasAuthorship W4283514077A5054911654 @default.
• W4283514077 hasAuthorship W4283514077A5062070780 @default.
• W4283514077 hasAuthorship W4283514077A5081900456 @default.
• W4283514077 hasConcept C126322002 @default.
• W4283514077 hasConcept C134018914 @default.
• W4283514077 hasConcept C141071460 @default.
• W4283514077 hasConcept C185592680 @default.
• W4283514077 hasConcept C187212893 @default.
• W4283514077 hasConcept C2776169613 @default.
• W4283514077 hasConcept C2776597655 @default.
• W4283514077 hasConcept C2777195454 @default.
• W4283514077 hasConcept C2777886399 @default.
• W4283514077 hasConcept C2778143274 @default.
• W4283514077 hasConcept C2779258352 @default.
• W4283514077 hasConcept C2985213535 @default.
• W4283514077 hasConcept C3017516299 @default.
• W4283514077 hasConcept C43617362 @default.
• W4283514077 hasConcept C44249647 @default.
• W4283514077 hasConcept C526584372 @default.
• W4283514077 hasConcept C54355233 @default.
• W4283514077 hasConcept C71315377 @default.
• W4283514077 hasConcept C71924100 @default.
• W4283514077 hasConcept C74414138 @default.
• W4283514077 hasConcept C86803240 @default.
• W4283514077 hasConceptScore W4283514077C126322002 @default.
• W4283514077 hasConceptScore W4283514077C134018914 @default.
• W4283514077 hasConceptScore W4283514077C141071460 @default.
• W4283514077 hasConceptScore W4283514077C185592680 @default.
• W4283514077 hasConceptScore W4283514077C187212893 @default.
• W4283514077 hasConceptScore W4283514077C2776169613 @default.
• W4283514077 hasConceptScore W4283514077C2776597655 @default.
• W4283514077 hasConceptScore W4283514077C2777195454 @default.
• W4283514077 hasConceptScore W4283514077C2777886399 @default.
• W4283514077 hasConceptScore W4283514077C2778143274 @default.
• W4283514077 hasConceptScore W4283514077C2779258352 @default.
• W4283514077 hasConceptScore W4283514077C2985213535 @default.
• W4283514077 hasConceptScore W4283514077C3017516299 @default.
• W4283514077 hasConceptScore W4283514077C43617362 @default.
• W4283514077 hasConceptScore W4283514077C44249647 @default.
• W4283514077 hasConceptScore W4283514077C526584372 @default.
• W4283514077 hasConceptScore W4283514077C54355233 @default.
• W4283514077 hasConceptScore W4283514077C71315377 @default.
• W4283514077 hasConceptScore W4283514077C71924100 @default.
• W4283514077 hasConceptScore W4283514077C74414138 @default.
• W4283514077 hasConceptScore W4283514077C86803240 @default.
• W4283514077 hasIssue "5" @default.
• W4283514077 hasLocation W42835140771 @default.
• W4283514077 hasLocation W42835140772 @default.
• W4283514077 hasOpenAccess W4283514077 @default.
• W4283514077 hasPrimaryLocation W42835140771 @default.
• W4283514077 hasRelatedWork W1975683900 @default.
• W4283514077 hasRelatedWork W1981780460 @default.
• W4283514077 hasRelatedWork W1988507778 @default.
• W4283514077 hasRelatedWork W2020688170 @default.
• W4283514077 hasRelatedWork W2108687096 @default.
• W4283514077 hasRelatedWork W2144744234 @default.
• W4283514077 hasRelatedWork W2409850457 @default.
• W4283514077 hasRelatedWork W4283514077 @default.
• W4283514077 hasRelatedWork W851836452 @default.

• next