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- W4283516993 abstract "In the thorax of higher vertebrates, ribs and intercostal muscles play a decisive role in stability and respiratory movements of the body wall. They are derivatives of the somites, the ribs originating in the sclerotome and the intercostal muscles originating in the myotome. During thorax development, ribs and intercostal muscles extend into the lateral plate mesoderm and eventually contact the sternum during ventral closure. Here, we give a detailed description of the morphogenesis of ribs and thoracic muscles in the chicken embryo (Gallus gallus). Using Alcian blue staining as well as Sox9 and Desmin whole-mount immunohistochemistry, we monitor synchronously the development of rib cartilage and intercostal muscle anlagen. We show that the muscle anlagen precede the rib anlagen during ventrolateral extension, which is in line with the inductive role of the myotome in rib differentiation. Our studies furthermore reveal the temporary formation of a previously unknown eighth rib in the chicken embryonic thorax." @default.
- W4283516993 created "2022-06-27" @default.
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- W4283516993 date "2022-06-25" @default.
- W4283516993 modified "2023-09-27" @default.
- W4283516993 title "Development of ribs and intercostal muscles in the chicken embryo" @default.
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- W4283516993 doi "https://doi.org/10.1111/joa.13716" @default.
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