Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283526504> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W4283526504 endingPage "9" @default.
- W4283526504 startingPage "1" @default.
- W4283526504 abstract "Metastasis is one of the characteristics of advanced cancer and the primary cause of cancer-related deaths from cancer, but the mechanism underlying metastasis is unclear, and there is a lack of metastasis markers. PTPRT is a protein-coding gene involved in both signal transduction and cellular adhesion. It is also known as a tumor suppressor gene that inhibits cell malignant proliferation by inhibiting the STAT3 pathway. Recent studies have reported that PTPRT is involved in the early metastatic seeding of colorectal cancer; however, the correlation between PTPRT and metastasis in other types of cancer has not been revealed. A combined analysis using a dataset from the genomics evidence neoplasia information exchange (GENIE) and cBioPortal revealed that PTPRT mutation is associated with poor prognosis in pan-cancer and non-small-cell lung cancer. The mutations of PTPRT or “gene modules” containing PTPRT are significantly enriched in patients with metastatic cancer in multiple cancers, suggesting that the PTPRT mutations serve as potential biomarkers of cancer metastasis." @default.
- W4283526504 created "2022-06-27" @default.
- W4283526504 creator A5004139569 @default.
- W4283526504 creator A5013740604 @default.
- W4283526504 creator A5016523671 @default.
- W4283526504 creator A5024767151 @default.
- W4283526504 creator A5067829807 @default.
- W4283526504 creator A5074951825 @default.
- W4283526504 date "2022-06-25" @default.
- W4283526504 modified "2023-10-14" @default.
- W4283526504 title "Association of PTPRT Mutations with Cancer Metastasis in Multiple Cancer Types" @default.
- W4283526504 cites W1536523521 @default.
- W4283526504 cites W1989545285 @default.
- W4283526504 cites W2011398963 @default.
- W4283526504 cites W2053931156 @default.
- W4283526504 cites W2092338119 @default.
- W4283526504 cites W2097924281 @default.
- W4283526504 cites W2099224719 @default.
- W4283526504 cites W2110574412 @default.
- W4283526504 cites W2110694683 @default.
- W4283526504 cites W2119568822 @default.
- W4283526504 cites W2131962318 @default.
- W4283526504 cites W2168688111 @default.
- W4283526504 cites W2287918349 @default.
- W4283526504 cites W2315243978 @default.
- W4283526504 cites W2508910949 @default.
- W4283526504 cites W2529308344 @default.
- W4283526504 cites W2615065404 @default.
- W4283526504 cites W2789856526 @default.
- W4283526504 cites W2794804602 @default.
- W4283526504 cites W2796408191 @default.
- W4283526504 cites W2805363059 @default.
- W4283526504 cites W2890888376 @default.
- W4283526504 cites W2913665794 @default.
- W4283526504 cites W2950945543 @default.
- W4283526504 cites W2977230685 @default.
- W4283526504 cites W3022777305 @default.
- W4283526504 cites W3094964061 @default.
- W4283526504 cites W3192622885 @default.
- W4283526504 cites W3216092566 @default.
- W4283526504 cites W3217485783 @default.
- W4283526504 cites W4200375058 @default.
- W4283526504 doi "https://doi.org/10.1155/2022/9386477" @default.
- W4283526504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35789644" @default.
- W4283526504 hasPublicationYear "2022" @default.
- W4283526504 type Work @default.
- W4283526504 citedByCount "1" @default.
- W4283526504 countsByYear W42835265042023 @default.
- W4283526504 crossrefType "journal-article" @default.
- W4283526504 hasAuthorship W4283526504A5004139569 @default.
- W4283526504 hasAuthorship W4283526504A5013740604 @default.
- W4283526504 hasAuthorship W4283526504A5016523671 @default.
- W4283526504 hasAuthorship W4283526504A5024767151 @default.
- W4283526504 hasAuthorship W4283526504A5067829807 @default.
- W4283526504 hasAuthorship W4283526504A5074951825 @default.
- W4283526504 hasBestOaLocation W42835265041 @default.
- W4283526504 hasConcept C121608353 @default.
- W4283526504 hasConcept C2779013556 @default.
- W4283526504 hasConcept C502942594 @default.
- W4283526504 hasConcept C526805850 @default.
- W4283526504 hasConcept C54355233 @default.
- W4283526504 hasConcept C71924100 @default.
- W4283526504 hasConcept C86803240 @default.
- W4283526504 hasConceptScore W4283526504C121608353 @default.
- W4283526504 hasConceptScore W4283526504C2779013556 @default.
- W4283526504 hasConceptScore W4283526504C502942594 @default.
- W4283526504 hasConceptScore W4283526504C526805850 @default.
- W4283526504 hasConceptScore W4283526504C54355233 @default.
- W4283526504 hasConceptScore W4283526504C71924100 @default.
- W4283526504 hasConceptScore W4283526504C86803240 @default.
- W4283526504 hasFunder F4320326705 @default.
- W4283526504 hasLocation W42835265041 @default.
- W4283526504 hasLocation W42835265042 @default.
- W4283526504 hasLocation W42835265043 @default.
- W4283526504 hasOpenAccess W4283526504 @default.
- W4283526504 hasPrimaryLocation W42835265041 @default.
- W4283526504 hasRelatedWork W1499339123 @default.
- W4283526504 hasRelatedWork W1970423756 @default.
- W4283526504 hasRelatedWork W2392730113 @default.
- W4283526504 hasRelatedWork W2732735609 @default.
- W4283526504 hasRelatedWork W3004259476 @default.
- W4283526504 hasRelatedWork W3032265334 @default.
- W4283526504 hasRelatedWork W3032784534 @default.
- W4283526504 hasRelatedWork W3144757235 @default.
- W4283526504 hasRelatedWork W3173207637 @default.
- W4283526504 hasRelatedWork W4304116770 @default.
- W4283526504 hasVolume "2022" @default.
- W4283526504 isParatext "false" @default.
- W4283526504 isRetracted "false" @default.
- W4283526504 workType "article" @default.