FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283589079> ?p ?o ?g. }

• W4283589079 endingPage "24" @default.
• W4283589079 startingPage "24.2" @default.
• W4283589079 abstract "Background Work participation among people with rheumatic and musculoskeletal diseases (RMDs) remains reduced when compared to the general population. A EULAR taskforce was established to agree on Points to Consider (PtC) to support people with RMD in healthy and sustainable work participation. Non-pharmacological interventions (NPI) could have an important role in improving work participation in RMDs. However, a comprehensive evidence synthesis of the effectiveness of NPIs in people with RMDs is lacking. Objectives To summarise the literature on effectiveness of NPIs on work participation in people with RMDs. Methods A search in four databases (MEDLINE, EMBASE, CENTRAL and CINAHL) was performed. Randomised Controlled Trials (RCTs) and Longitudinal Observational Studies (LOS) assessing non-pharmacological/non-surgical interventions until August 2020 were screened. Studies including people with any RMD (except low back pain or work-related RMDs) and assessing a work participation outcome domain (sick leave, work status, presenteeism) were considered eligible. For qualitative evidence synthesis, RCTs and LOS were considered. For quantitative evidence synthesis, only RCTs were considered. For each randomized comparison, standardised mean differences (SMDs) were calculated for the three outcome domains and used as effect size in the meta-analyses; i.e. a negative SMD favouring the NPI over control. Next, Mixed Effects Meta-Regression Analyses were performed, with random effects for randomised comparisons, and a fixed effect factor for the stratified subgroups of clinical interest. Subgroups within diseases (musculoskeletal pain disorders vs. other types of RMDs), risk status for sick leave at baseline (on sick leave or at risk for sick leave; not at risk for sick leave; a combination; or not specified) and single vs. multiple component NPIs were pre-defined. Risk of Bias (RoB) of RCTs was assessed using the Cochrain tool. Results Out of 8,864 records, 64 studies (71 treatment comparisons) were included. Studies usually included a mixed population of several RMDs (42%). Most NPIs were conducted in a clinical setting (n=44, 62%) and NPIs usually had multiple components (n=57, 80%), such as vocational support combined with physical training (n=18, 25%). Sick leave was the most frequently reported outcome domain (n=56, 88%). In the qualitative syntheses, 30%/50%/29% of interventions were considered plausible in improving sick leave, work status and presenteeism, respectively. In the quantitative synthesis, NPIs (37 RCTs, 42 comparisons with mostly moderate to high RoB) showed small to moderate effect sizes, favouring NPIs over comparators for sick leave (SMD=-0.23, 95%CI -0.33 to -0.13), work status (SMD=-0.38, 95%CI -0.63 to -0.12) and presenteeism (SMD=-0.25, 95%CI -0.39 to -0.12). The forest plot for sick leave is shown (Figure 1). Subgroup analyses for sick leave revealed that, compared to control, NPIs were not effective in musculoskeletal pain disorders, in contrast to the other types of RMDs. For both other subgroup analyses (baseline risk for sick leave; single vs. multicomponent NPI), NPIs improved sick leave similarly in subgroups compared to the control. Subgroup analyses for work status and presenteeism had generally similar effects in subgroups, but the interpretation requires caution in view of the small number of comparisons. Of note, clinical and methodological heterogeneity between studies was substantial, with some concerns about methodological quality related blinding and completeness of follow up. Conclusion Overall, NPIs seem to have significant, but on the average population level only small to moderate effects on sick leave, work status and presenteeism in RMDs. However, effects on sick leave varied substantially between subgroups. This synthesis suggests that tailoring NPIs to individuals’ needs and context could be clinically valuable. Disclosure of Interests None declared." @default.
• W4283589079 created "2022-06-28" @default.
• W4283589079 creator A5018393429 @default.
• W4283589079 creator A5022459181 @default.
• W4283589079 creator A5028817810 @default.
• W4283589079 creator A5057971383 @default.
• W4283589079 creator A5062170314 @default.
• W4283589079 creator A5073983810 @default.
• W4283589079 creator A5076573159 @default.
• W4283589079 creator A5082212795 @default.
• W4283589079 date "2022-05-23" @default.
• W4283589079 modified "2023-09-30" @default.
• W4283589079 title "OP0033 EFFECTIVENESS OF NON-PHARMACOLOGICAL INTERVENTIONS TO PROMOTE WORK PARTICIPATION IN PEOPLE WITH RMDs: A SYSTEMATIC REVIEW AND META-ANALYSIS" @default.
• W4283589079 doi "https://doi.org/10.1136/annrheumdis-2022-eular.978" @default.
• W4283589079 hasPublicationYear "2022" @default.
• W4283589079 type Work @default.
• W4283589079 citedByCount "1" @default.
• W4283589079 countsByYear W42835890792022 @default.
• W4283589079 crossrefType "journal-article" @default.
• W4283589079 hasAuthorship W4283589079A5018393429 @default.
• W4283589079 hasAuthorship W4283589079A5022459181 @default.
• W4283589079 hasAuthorship W4283589079A5028817810 @default.
• W4283589079 hasAuthorship W4283589079A5057971383 @default.
• W4283589079 hasAuthorship W4283589079A5062170314 @default.
• W4283589079 hasAuthorship W4283589079A5073983810 @default.
• W4283589079 hasAuthorship W4283589079A5076573159 @default.
• W4283589079 hasAuthorship W4283589079A5082212795 @default.
• W4283589079 hasBestOaLocation W42835890791 @default.
• W4283589079 hasConcept C126322002 @default.
• W4283589079 hasConcept C15744967 @default.
• W4283589079 hasConcept C159110408 @default.
• W4283589079 hasConcept C168563851 @default.
• W4283589079 hasConcept C17744445 @default.
• W4283589079 hasConcept C1862650 @default.
• W4283589079 hasConcept C199539241 @default.
• W4283589079 hasConcept C23131810 @default.
• W4283589079 hasConcept C27400517 @default.
• W4283589079 hasConcept C27415008 @default.
• W4283589079 hasConcept C2776737852 @default.
• W4283589079 hasConcept C2779382274 @default.
• W4283589079 hasConcept C2779473830 @default.
• W4283589079 hasConcept C2781145037 @default.
• W4283589079 hasConcept C2908647359 @default.
• W4283589079 hasConcept C71924100 @default.
• W4283589079 hasConcept C77805123 @default.
• W4283589079 hasConcept C95190672 @default.
• W4283589079 hasConcept C99454951 @default.
• W4283589079 hasConceptScore W4283589079C126322002 @default.
• W4283589079 hasConceptScore W4283589079C15744967 @default.
• W4283589079 hasConceptScore W4283589079C159110408 @default.
• W4283589079 hasConceptScore W4283589079C168563851 @default.
• W4283589079 hasConceptScore W4283589079C17744445 @default.
• W4283589079 hasConceptScore W4283589079C1862650 @default.
• W4283589079 hasConceptScore W4283589079C199539241 @default.
• W4283589079 hasConceptScore W4283589079C23131810 @default.
• W4283589079 hasConceptScore W4283589079C27400517 @default.
• W4283589079 hasConceptScore W4283589079C27415008 @default.
• W4283589079 hasConceptScore W4283589079C2776737852 @default.
• W4283589079 hasConceptScore W4283589079C2779382274 @default.
• W4283589079 hasConceptScore W4283589079C2779473830 @default.
• W4283589079 hasConceptScore W4283589079C2781145037 @default.
• W4283589079 hasConceptScore W4283589079C2908647359 @default.
• W4283589079 hasConceptScore W4283589079C71924100 @default.
• W4283589079 hasConceptScore W4283589079C77805123 @default.
• W4283589079 hasConceptScore W4283589079C95190672 @default.
• W4283589079 hasConceptScore W4283589079C99454951 @default.
• W4283589079 hasIssue "Suppl 1" @default.
• W4283589079 hasLocation W42835890791 @default.
• W4283589079 hasOpenAccess W4283589079 @default.
• W4283589079 hasPrimaryLocation W42835890791 @default.
• W4283589079 hasRelatedWork W2147801106 @default.
• W4283589079 hasRelatedWork W2226160317 @default.
• W4283589079 hasRelatedWork W2322301818 @default.
• W4283589079 hasRelatedWork W2550283493 @default.
• W4283589079 hasRelatedWork W2802402120 @default.
• W4283589079 hasRelatedWork W2909281065 @default.
• W4283589079 hasRelatedWork W3004034044 @default.
• W4283589079 hasRelatedWork W3034637963 @default.
• W4283589079 hasRelatedWork W3035857423 @default.
• W4283589079 hasRelatedWork W4226056541 @default.
• W4283589079 hasVolume "81" @default.
• W4283589079 isParatext "false" @default.
• W4283589079 isRetracted "false" @default.
• W4283589079 workType "article" @default.