FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283640058> ?p ?o ?g. }

• W4283640058 abstract "Childhood Hodgkin lymphoma survivors suffer from long-term effects decades after treatment completion with a prevalence of pulmonary dysfunction of up to 65.2%.This study explored the early trajectory of pulmonary function in pediatric cancer patients with Hodgkin lymphoma who received pulmonary toxic therapy.In this single-center, 20-year retrospective cohort study, we included patients who were <18 years old at diagnosis of Hodgkin lymphoma between January 1994 and December 2014, and received bleomycin or thoracic radiation. We measured pulmonary function and reported on percent predicted values for forced expiratory volume in 1 s, total lung capacity, and diffusing capacity of the lungs. We used linear mixed models to identify the association of clinical factors with longitudinal changes in lung function at time points before and after treatment completion. Of 80 children who met inclusion criteria, all were treated with bleomycin, and 83.8% received thoracic radiation. More than half (51.2%) of patients had any abnormalities in lung function measures during the study observation period which averaged 24.2 months (±31.1SD). Females, younger age at diagnosis and treatment with radiation were associated with lower lung function measurements at various time points. While the majority of children experienced a recovery of their lung function within 1-2 years after treatment completion, some children with these risk factors did not.Pulmonary function abnormalities begin early in children treated for Hodgkin lymphoma. While the majority of children demonstrate a slow and continuous improvement in lung function back to baseline over time, we recommend routine asymptomatic screening of pulmonary function in certain childhood cancer survivors, particularly females, those diagnosed young and patients who received radiation therapy." @default.
• W4283640058 created "2022-06-29" @default.
• W4283640058 creator A5021305661 @default.
• W4283640058 creator A5021994881 @default.
• W4283640058 creator A5024176321 @default.
• W4283640058 creator A5025932181 @default.
• W4283640058 creator A5027209386 @default.
• W4283640058 creator A5039715269 @default.
• W4283640058 creator A5072352456 @default.
• W4283640058 creator A5072544703 @default.
• W4283640058 creator A5085010257 @default.
• W4283640058 date "2022-06-27" @default.
• W4283640058 modified "2023-10-06" @default.
• W4283640058 title "A longitudinal analysis of early lung function trajectory in survivors of childhood Hodgkin lymphoma" @default.
• W4283640058 cites W1514716841 @default.
• W4283640058 cites W1983528426 @default.
• W4283640058 cites W1985174090 @default.
• W4283640058 cites W1988228415 @default.
• W4283640058 cites W1988416535 @default.
• W4283640058 cites W2003686854 @default.
• W4283640058 cites W2014432477 @default.
• W4283640058 cites W2014731229 @default.
• W4283640058 cites W2016149705 @default.
• W4283640058 cites W2021912098 @default.
• W4283640058 cites W2051435645 @default.
• W4283640058 cites W2053394877 @default.
• W4283640058 cites W2063177484 @default.
• W4283640058 cites W2079802658 @default.
• W4283640058 cites W2086492299 @default.
• W4283640058 cites W2092718150 @default.
• W4283640058 cites W2099297962 @default.
• W4283640058 cites W2099668669 @default.
• W4283640058 cites W2108363413 @default.
• W4283640058 cites W2127785304 @default.
• W4283640058 cites W2131122365 @default.
• W4283640058 cites W2133026053 @default.
• W4283640058 cites W2139319738 @default.
• W4283640058 cites W2141008180 @default.
• W4283640058 cites W2157627821 @default.
• W4283640058 cites W2161569722 @default.
• W4283640058 cites W2308102069 @default.
• W4283640058 cites W2344368041 @default.
• W4283640058 cites W2599076725 @default.
• W4283640058 cites W2752414510 @default.
• W4283640058 cites W2773049281 @default.
• W4283640058 cites W4283640058 @default.
• W4283640058 cites W4294116629 @default.
• W4283640058 cites W4300709251 @default.
• W4283640058 doi "https://doi.org/10.1002/cnr2.1661" @default.
• W4283640058 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35760768" @default.
• W4283640058 hasPublicationYear "2022" @default.
• W4283640058 type Work @default.
• W4283640058 citedByCount "2" @default.
• W4283640058 countsByYear W42836400582022 @default.
• W4283640058 countsByYear W42836400582023 @default.
• W4283640058 crossrefType "journal-article" @default.
• W4283640058 hasAuthorship W4283640058A5021305661 @default.
• W4283640058 hasAuthorship W4283640058A5021994881 @default.
• W4283640058 hasAuthorship W4283640058A5024176321 @default.
• W4283640058 hasAuthorship W4283640058A5025932181 @default.
• W4283640058 hasAuthorship W4283640058A5027209386 @default.
• W4283640058 hasAuthorship W4283640058A5039715269 @default.
• W4283640058 hasAuthorship W4283640058A5072352456 @default.
• W4283640058 hasAuthorship W4283640058A5072544703 @default.
• W4283640058 hasAuthorship W4283640058A5085010257 @default.
• W4283640058 hasBestOaLocation W42836400581 @default.
• W4283640058 hasConcept C126322002 @default.
• W4283640058 hasConcept C141071460 @default.
• W4283640058 hasConcept C165637977 @default.
• W4283640058 hasConcept C187212893 @default.
• W4283640058 hasConcept C27101514 @default.
• W4283640058 hasConcept C2776232574 @default.
• W4283640058 hasConcept C2776256026 @default.
• W4283640058 hasConcept C2776694085 @default.
• W4283640058 hasConcept C2777714996 @default.
• W4283640058 hasConcept C2777910003 @default.
• W4283640058 hasConcept C2779338263 @default.
• W4283640058 hasConcept C3018587741 @default.
• W4283640058 hasConcept C509974204 @default.
• W4283640058 hasConcept C55520419 @default.
• W4283640058 hasConcept C71924100 @default.
• W4283640058 hasConcept C72563966 @default.
• W4283640058 hasConcept C75603125 @default.
• W4283640058 hasConceptScore W4283640058C126322002 @default.
• W4283640058 hasConceptScore W4283640058C141071460 @default.
• W4283640058 hasConceptScore W4283640058C165637977 @default.
• W4283640058 hasConceptScore W4283640058C187212893 @default.
• W4283640058 hasConceptScore W4283640058C27101514 @default.
• W4283640058 hasConceptScore W4283640058C2776232574 @default.
• W4283640058 hasConceptScore W4283640058C2776256026 @default.
• W4283640058 hasConceptScore W4283640058C2776694085 @default.
• W4283640058 hasConceptScore W4283640058C2777714996 @default.
• W4283640058 hasConceptScore W4283640058C2777910003 @default.
• W4283640058 hasConceptScore W4283640058C2779338263 @default.
• W4283640058 hasConceptScore W4283640058C3018587741 @default.
• W4283640058 hasConceptScore W4283640058C509974204 @default.
• W4283640058 hasConceptScore W4283640058C55520419 @default.
• W4283640058 hasConceptScore W4283640058C71924100 @default.
• W4283640058 hasConceptScore W4283640058C72563966 @default.
• W4283640058 hasConceptScore W4283640058C75603125 @default.

• next