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- W4283640897 abstract "When drafting this month's editorial, it is still early-mid June, and many of the cytometry family had finally enjoyed after years of absence and separation the recent in-person meeting at the latest CYTO in Philadelphia. According to my non-representative on-site survey, this was for the majority of participants the first meeting in 3D since early 2020. It was obvious that none missed the time where the colleagues were only visible in rectangles during a remote conference. What a difference and what a great hub and motivation for exchanging new ideas and finally touch base with all. For this July issue, I have chosen the Original Article by Mestrum and colleagues on “Proliferative and anti-apoptotic fractions in maturing hematopoietic cell lineages and their role in homeostasis of normal bone marrow.” This is my favorite paper of the month. Herein, the authors combined classical methods for determining cell proliferation capacity, the Ki-67 index, and anti-apoptotic capacity, the Bcl-2 protein index, for cell development analysis of progenitor cells in the human bone marrow. The method they used was already published earlier by the group, but in the present work, they applied a further refined and validated approach. Using their technology, the authors describe different progenitors of erythropoiesis, myelopoiesis, and monopoiesis maturation pathways including the loss of the Ki-67 and Bcl-2 fractions. Finally, they provide information on the potential clinical significance of their findings. I hope you enjoy reading as I did. Finally, I would like to inform you that our excellent Associate Editor for Microbiology, Prof Dr Susi Müller, board member of Cytometry Part A since 2007, announced her retreat from the editorial board. I want to thank our outgoing AE for her exceptional support of the journal, managing a great number of manuscripts, and above all, initiating highly recognized special issues and publication of research manuscripts. One of her publications from 2007 on the usefulness of propidium iodide for cell viability of bacteria turned out to be evergreen, cited 24 times in 2021 alone [1]. Susi Müller proposed Dr Susanne Dunker to fill the gap she is leaving as AE for Cytometry Part A, and Dr Dunker started her work last year." @default.
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- W4283640897 date "2022-06-28" @default.
- W4283640897 modified "2023-10-16" @default.
- W4283640897 title "CYTO reloaded" @default.
- W4283640897 cites W2080228586 @default.
- W4283640897 doi "https://doi.org/10.1002/cyto.a.24666" @default.
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