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• W4283688524 abstract "Objective To assess hearing outcomes in observed vestibular schwannoma (VS) with focus on non-growing tumors. Study Design Retrospective review. Setting Two tertiary neurotology centers. Patients and Interventions Patients with sporadic VS undergoing at least 3 years’ observation. Main Outcome Measures Changes in pure tone averages (PTA) and word recognition scores (WRS) normalized to the contralateral ear. Results During the study period, 39 of 105 included patients (37.1%) had tumor growth. Patients with tumor growth had a mean normalized increase in PTA of 8.0 dB HL ( p = 0.008) corresponding to a normalized average worsening of their PTA of 1.8 dB per year. Patients with non-growing tumors less than 5 mm in maximal dimension did not have significant ongoing normalized hearing loss ( p > 0.05). Patients with non-growing tumors more than or equal to 5 mm had a mean normalized increase in PTA of 7.4 dB HL ( p = 0.001) corresponding to an average of 2.0 dB HL per year, which was similar to the loss observed in growing tumors regardless of size ( p > 0.05). Normalized decline in PTA of at least 5 dB HL was seen in 72% of patients with growing tumors, 53% of patients with nongrowing tumors more than or equal to 5 mm, and 38% of patients with non-growing tumors less than 5 mm. Conclusions A long-term analysis of hearing outcomes in observed vestibular schwannoma is presented. With observation, VS more than or equal to 5 mm is associated with continued hearing loss even without tumor growth, while non-growing tumors less than 5 mm are not associated with continuing hearing loss. These data inform expectations for observed VS for providers and patients." @default.
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• W4283688524 date "2022-06-29" @default.
• W4283688524 modified "2023-10-17" @default.
• W4283688524 title "Progression of Hearing Loss in Observed Non-Growing Vestibular Schwannoma" @default.
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• W4283688524 doi "https://doi.org/10.1097/mao.0000000000003563" @default.
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