Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283700635> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4283700635 endingPage "1558" @default.
- W4283700635 startingPage "1558.1" @default.
- W4283700635 abstract "Background Spondyloarthritis (SpA) is a chronic inflammatory disease that predominantly affects the sacroiliac joints and the spine. Patients with SpA have an increased risk of osteoporosis and fracture resulting from a combination of inflammation and immobility. The non-radiographic form for SpA (nr-axSpA) has the same predictors factors of bone fragility however the real fracture risk is unknown in this phenotype. Objectives This study aims to investigate BMD and the Fracture Risk Assessment Tool (FRAX) in patients with nr-axSpA. Methods We conducted a retrospective study including 40 patients with nr-axSpA, according to the ASAS criteria. For the enrolled patient, we collected the clinical and biological data. We calculated the disease activity using the Bath Ankylosing Spondylitis disease activity (BASDAI) and the Ankylosing Spondylitis Disease Activity Score (ASDAS). Functional impairment was assessed by the Ankylosing Spondylitis Functional Index (BASFI). We measured the bone mineral density using the dual-energy X-ray absorptiometry (DXA) in the anteroposterior lumbar, lateral spine, and hip neck. The ten-year probability of major osteoporotic fracture was calculated using the Tunisian version of Fracture Risk Assessment Tool (FRAX). Results Twenty-seven women (67.5%) and thirteen men (32.5%) were enrolled. The mean age was 41.5 years (±11.2), and the mean disease duration was 3,1 years (±2.7). The mean BASDAI and ASDAS CRP was 4.7 ± 2.2 and 3.27 ± 1.29, respectively. The mean BASFI was 3.6 ± 2.5. According to World Health Organization (WHO) criteria, 45% of patients displayed osteopenia and 30% osteoporosis. The mean major osteoporotic fracture (MOF) score was 0,09 ± 0,25 [0-1,3]. The MOF was significantly associated with BMD (p=0.000). The variables associated with MOF were a high physician’s global assessment score, a high BASFI, and female gender, but without significant relation. However, no correlation was found between the MOF and the disease duration, the presence of peripheral arthritis or enthesitis, and the ASDAS. Conclusion In nr-axSpA, patients with low BMD had a higher calculated 10-year fracture risk. FRAX score is related to functional impairment and gender. Disease activity does not affect the probability of fracture. Disclosure of Interests None declared" @default.
- W4283700635 created "2022-06-30" @default.
- W4283700635 creator A5002876760 @default.
- W4283700635 creator A5018976072 @default.
- W4283700635 creator A5022000887 @default.
- W4283700635 creator A5053491564 @default.
- W4283700635 creator A5069412752 @default.
- W4283700635 creator A5071525778 @default.
- W4283700635 creator A5079608009 @default.
- W4283700635 date "2022-05-23" @default.
- W4283700635 modified "2023-09-25" @default.
- W4283700635 title "AB0870 ASSESSMENT OF FRACTURE RISK IN PATIENTS WITH NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS" @default.
- W4283700635 doi "https://doi.org/10.1136/annrheumdis-2022-eular.4807" @default.
- W4283700635 hasPublicationYear "2022" @default.
- W4283700635 type Work @default.
- W4283700635 citedByCount "0" @default.
- W4283700635 crossrefType "journal-article" @default.
- W4283700635 hasAuthorship W4283700635A5002876760 @default.
- W4283700635 hasAuthorship W4283700635A5018976072 @default.
- W4283700635 hasAuthorship W4283700635A5022000887 @default.
- W4283700635 hasAuthorship W4283700635A5053491564 @default.
- W4283700635 hasAuthorship W4283700635A5069412752 @default.
- W4283700635 hasAuthorship W4283700635A5071525778 @default.
- W4283700635 hasAuthorship W4283700635A5079608009 @default.
- W4283700635 hasBestOaLocation W42837006351 @default.
- W4283700635 hasConcept C126322002 @default.
- W4283700635 hasConcept C1862650 @default.
- W4283700635 hasConcept C198451711 @default.
- W4283700635 hasConcept C2775854910 @default.
- W4283700635 hasConcept C2776260265 @default.
- W4283700635 hasConcept C2776541429 @default.
- W4283700635 hasConcept C2776886416 @default.
- W4283700635 hasConcept C2777083390 @default.
- W4283700635 hasConcept C2777402515 @default.
- W4283700635 hasConcept C2777453003 @default.
- W4283700635 hasConcept C2777525943 @default.
- W4283700635 hasConcept C2779134260 @default.
- W4283700635 hasConcept C2779329777 @default.
- W4283700635 hasConcept C2780415856 @default.
- W4283700635 hasConcept C2994343686 @default.
- W4283700635 hasConcept C71924100 @default.
- W4283700635 hasConceptScore W4283700635C126322002 @default.
- W4283700635 hasConceptScore W4283700635C1862650 @default.
- W4283700635 hasConceptScore W4283700635C198451711 @default.
- W4283700635 hasConceptScore W4283700635C2775854910 @default.
- W4283700635 hasConceptScore W4283700635C2776260265 @default.
- W4283700635 hasConceptScore W4283700635C2776541429 @default.
- W4283700635 hasConceptScore W4283700635C2776886416 @default.
- W4283700635 hasConceptScore W4283700635C2777083390 @default.
- W4283700635 hasConceptScore W4283700635C2777402515 @default.
- W4283700635 hasConceptScore W4283700635C2777453003 @default.
- W4283700635 hasConceptScore W4283700635C2777525943 @default.
- W4283700635 hasConceptScore W4283700635C2779134260 @default.
- W4283700635 hasConceptScore W4283700635C2779329777 @default.
- W4283700635 hasConceptScore W4283700635C2780415856 @default.
- W4283700635 hasConceptScore W4283700635C2994343686 @default.
- W4283700635 hasConceptScore W4283700635C71924100 @default.
- W4283700635 hasIssue "Suppl 1" @default.
- W4283700635 hasLocation W42837006351 @default.
- W4283700635 hasOpenAccess W4283700635 @default.
- W4283700635 hasPrimaryLocation W42837006351 @default.
- W4283700635 hasRelatedWork W2009618852 @default.
- W4283700635 hasRelatedWork W2059944559 @default.
- W4283700635 hasRelatedWork W2073878530 @default.
- W4283700635 hasRelatedWork W2350835427 @default.
- W4283700635 hasRelatedWork W2364010762 @default.
- W4283700635 hasRelatedWork W2582646688 @default.
- W4283700635 hasRelatedWork W2955419479 @default.
- W4283700635 hasRelatedWork W3040608001 @default.
- W4283700635 hasRelatedWork W4283700635 @default.
- W4283700635 hasRelatedWork W2182784462 @default.
- W4283700635 hasVolume "81" @default.
- W4283700635 isParatext "false" @default.
- W4283700635 isRetracted "false" @default.
- W4283700635 workType "article" @default.