Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283709436> ?p ?o ?g. }
- W4283709436 abstract "Probiotics have received widespread attention as a healthy ingredient. The preventive effect of Bifidobacterium lactis TY-S01 on loperamide-induced constipation in mice was investigated in this study. TY-S01 accelerated the peristalsis of intestine, maintained the humidity of faeces, and prevented the destruction of gut barrier. TY-S01 also maintained the 5-HT, MTL and SP at normal levels in constipated mice. Simultaneously, TY-S01 up-regulated the mRNA expressions of 5-HT4R, SERT, and MUC-2, while down-regulated the mRNA expressions of pro-inflammatory genes remarkably. The levels of short-chain fatty acids in the feces of constipated mice were also increased because of the intervention with TY-S01. Moreover, TY-S01 prevented gut microbiological dysbiosis in constipated mice. Spearman's correlation analysis revealed that there was an obvious association between metabolic biomarkers and gut microbiota. In summary, TY-S01 regulated gut microbiota and the production of intestinal metabolites to prevent loperamide-induced constipation." @default.
- W4283709436 created "2022-06-30" @default.
- W4283709436 creator A5014852141 @default.
- W4283709436 creator A5037677450 @default.
- W4283709436 creator A5045839676 @default.
- W4283709436 creator A5050860854 @default.
- W4283709436 creator A5051717124 @default.
- W4283709436 creator A5052274720 @default.
- W4283709436 creator A5057931640 @default.
- W4283709436 creator A5064534354 @default.
- W4283709436 creator A5071771404 @default.
- W4283709436 date "2022-06-29" @default.
- W4283709436 modified "2023-09-30" @default.
- W4283709436 title "Bifidobacterium lactis TY-S01 Prevents Loperamide-Induced Constipation by Modulating Gut Microbiota and Its Metabolites in Mice" @default.
- W4283709436 cites W142609610 @default.
- W4283709436 cites W1563205988 @default.
- W4283709436 cites W1883178470 @default.
- W4283709436 cites W1966335258 @default.
- W4283709436 cites W1970757039 @default.
- W4283709436 cites W1975714633 @default.
- W4283709436 cites W1988687339 @default.
- W4283709436 cites W1994914640 @default.
- W4283709436 cites W1996852467 @default.
- W4283709436 cites W1999711567 @default.
- W4283709436 cites W2012951812 @default.
- W4283709436 cites W2031693514 @default.
- W4283709436 cites W2033064171 @default.
- W4283709436 cites W2052606774 @default.
- W4283709436 cites W2057086524 @default.
- W4283709436 cites W2060185417 @default.
- W4283709436 cites W2077257269 @default.
- W4283709436 cites W2106855445 @default.
- W4283709436 cites W2120762987 @default.
- W4283709436 cites W2122935354 @default.
- W4283709436 cites W2148422863 @default.
- W4283709436 cites W2159622087 @default.
- W4283709436 cites W2162782553 @default.
- W4283709436 cites W2164393508 @default.
- W4283709436 cites W2188834486 @default.
- W4283709436 cites W2201142633 @default.
- W4283709436 cites W2236332835 @default.
- W4283709436 cites W2327707893 @default.
- W4283709436 cites W2551639289 @default.
- W4283709436 cites W2578716113 @default.
- W4283709436 cites W2607034253 @default.
- W4283709436 cites W2615801135 @default.
- W4283709436 cites W2618397805 @default.
- W4283709436 cites W2748998801 @default.
- W4283709436 cites W2750390448 @default.
- W4283709436 cites W2793840364 @default.
- W4283709436 cites W2888508985 @default.
- W4283709436 cites W2897071318 @default.
- W4283709436 cites W2951351243 @default.
- W4283709436 cites W2954297441 @default.
- W4283709436 cites W3008699240 @default.
- W4283709436 cites W3016414734 @default.
- W4283709436 cites W3111799587 @default.
- W4283709436 cites W3112940040 @default.
- W4283709436 cites W3113335726 @default.
- W4283709436 cites W3174028200 @default.
- W4283709436 doi "https://doi.org/10.3389/fnut.2022.890314" @default.
- W4283709436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35845767" @default.
- W4283709436 hasPublicationYear "2022" @default.
- W4283709436 type Work @default.
- W4283709436 citedByCount "6" @default.
- W4283709436 countsByYear W42837094362022 @default.
- W4283709436 countsByYear W42837094362023 @default.
- W4283709436 crossrefType "journal-article" @default.
- W4283709436 hasAuthorship W4283709436A5014852141 @default.
- W4283709436 hasAuthorship W4283709436A5037677450 @default.
- W4283709436 hasAuthorship W4283709436A5045839676 @default.
- W4283709436 hasAuthorship W4283709436A5050860854 @default.
- W4283709436 hasAuthorship W4283709436A5051717124 @default.
- W4283709436 hasAuthorship W4283709436A5052274720 @default.
- W4283709436 hasAuthorship W4283709436A5057931640 @default.
- W4283709436 hasAuthorship W4283709436A5064534354 @default.
- W4283709436 hasAuthorship W4283709436A5071771404 @default.
- W4283709436 hasBestOaLocation W42837094361 @default.
- W4283709436 hasConcept C126322002 @default.
- W4283709436 hasConcept C203014093 @default.
- W4283709436 hasConcept C2777165150 @default.
- W4283709436 hasConcept C2777573665 @default.
- W4283709436 hasConcept C2779802037 @default.
- W4283709436 hasConcept C2780206646 @default.
- W4283709436 hasConcept C2780305828 @default.
- W4283709436 hasConcept C2781112942 @default.
- W4283709436 hasConcept C523546767 @default.
- W4283709436 hasConcept C539455810 @default.
- W4283709436 hasConcept C54355233 @default.
- W4283709436 hasConcept C61716771 @default.
- W4283709436 hasConcept C71924100 @default.
- W4283709436 hasConcept C86803240 @default.
- W4283709436 hasConcept C89423630 @default.
- W4283709436 hasConceptScore W4283709436C126322002 @default.
- W4283709436 hasConceptScore W4283709436C203014093 @default.
- W4283709436 hasConceptScore W4283709436C2777165150 @default.
- W4283709436 hasConceptScore W4283709436C2777573665 @default.
- W4283709436 hasConceptScore W4283709436C2779802037 @default.
- W4283709436 hasConceptScore W4283709436C2780206646 @default.
- W4283709436 hasConceptScore W4283709436C2780305828 @default.