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• W4283711231 endingPage "100417" @default.
• W4283711231 startingPage "100417" @default.
• W4283711231 abstract "A facile method for the reduction of carboxylic acid group of Bezafibrate, an approved drug, is described. The selective reduction of carboxylic acid group to corresponding alcohol was carried out by activation of the carboxylic acid moiety via mixed anhydride followed by the addition of stoichiometric amount of NaBH4 and methanol to obtain the first alcohol variant of Bezafibrate. The reaction was completed in 5-10 min in excellent yield and purity. The new alcohol derivative was characterized by spectroscopic methods. This is the first report on this new molecule." @default.
• W4283711231 created "2022-06-30" @default.
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• W4283711231 date "2022-01-01" @default.
• W4283711231 modified "2023-10-01" @default.
• W4283711231 title "A facile and chemoselectivity in synthesis of 4-chloro-N-(4-((1-hydroxy-2-methylpropan-2-yl)oxy)phenethyl)benzamide, the alcohol derivative of Bezafibrate" @default.
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• W4283711231 doi "https://doi.org/10.1016/j.rechem.2022.100417" @default.
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