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- W4283713123 abstract "Background Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in childhood and presents predominantly with peripheral arthritis; this pathology is divided into subgroups. In Colombia there are few descriptive studies. Objectives The objective was to describe the sociodemographic, immunological and clinical characteristics of a cohort of patients with Juvenile Idiopathic Arthritis. Methods An observational cross-sectional study was conducted that included 171 JIA patients treated at a specialized rheumatology institution between 2010 and 2021. Univariate analyzes were performed to describe the sociodemographic, immunological, and clinical profile of the population. The epidemiological characteristics were obtained from the review of medical reports. Results 171 patients were analyzed. 58.48% were women; with a median age at diagnosis of 12.25 years (IQR=6.55), and a median duration of the disease of 3.71 years (IQR=5.52). According to the classification criteria of the International League of Associations for Rheumatism (ILAR), the most frequent were enthesitis related to JIA present in 61 patients (35.67%), oligoarticular 27 (15.79%), negative polyarticular rheumatoid factor (14.62%) and positive polyarticular rheumatoid factor (14.04%). JIA-enthesitis related was 17,85% ANAs positive, 16,66% rheumatoid factor positive and HLA-B27 en 22,72%. In JIA oligoarticular the auto-antibodies ANAS, FR was present in 26,32% and 16,66%. The JIA-polyarticular rheumatoid factor positive was positive for ANA in 76.47% and AntiCCP in 88.88%. JIA-polyarticular rheumatoid factor negative was positive for ANAs (40%) and AntiCCP (10%). Conclusion The epidemiological description of JIA in the Colombian population is similar to the current one in other populations, but we found differences in the subtypes of juvenile idiopathic arthritis and in the presence of autoantibodies. This is the first step to discover the characteristics of this autoimmune disease in this population. Disclosure of Interests Miguel Dario Canola Escobar: None declared, DANIEL RODRIGUEZ-ARIZA: None declared, LUIS AARON-INFANTE: None declared, DIANA CARDONA: None declared, YADITH HERNANDEZ-ARENAS: None declared, DIEGO MELO: None declared, JUAN PUENTES: None declared, PAULA ROZO-TELLEZ: None declared, Veronica Usuga-Graciano: None declared, OLGA ARIZA-QUINTERO Employee of: actual employee in Novartis Colombia as medical science liaison" @default.
- W4283713123 created "2022-06-30" @default.
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- W4283713123 date "2022-05-23" @default.
- W4283713123 modified "2023-09-26" @default.
- W4283713123 title "AB1467 EPIDEMIOLOGICAL DESCRIPTION OF JUVENILE IDIOPATHIC ARTHRITIS FROM A COLOMBIAN POPULATION" @default.
- W4283713123 doi "https://doi.org/10.1136/annrheumdis-2022-eular.5401" @default.
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