Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283724369> ?p ?o ?g. }
- W4283724369 abstract "Dietary nucleotides [inclusion adenosine 5'-monophosphate (AMP)] supplementation was shown to promote the feed intake of sows and increase the AMP content in their milk in our previous work, but whether AMP shapes the energy expenditure and lipid metabolism in mammals remains unknown. Here, we aimed to explore the effects and the related mechanism of dietary AMP supplementation on food intake, body composition, energy expenditure, and lipid metabolism in male mice.4-week-old C57BL/6 mice (After a 1-wk adaptation) were fed with basal diet and basal diet supplemented with 0.1% AMP, respectively. Animal food intake and body weight were monitored and after 4 weeks all animals were sacrificed to measure the body composition, energy expenditure and lipid metabolism changes.Compared with the control, the 0.1% AMP fed mice showed higher food intake while lower adipose weight. Intriguingly, dietary AMP supplementation was found to stimulate brown adipose tissue thermogenesis as evidenced by the increase in the uncoupling protein-1 level and the core temperature. Moreover, AMP supplementation was shown to promote white adipose tissue lipolysis as indicated by smaller lipid droplet size in mice. These results demonstrate that dietary AMP supplementation could enhance oxygen consumption and energy expenditure.This study highlights the physiological importance of AMP supplementation in mediating food intake and energy expenditure and suggests its potential as an adjuvant therapy in preventing energy metabolic disorders (mainly obesity and diabetes)." @default.
- W4283724369 created "2022-07-01" @default.
- W4283724369 creator A5000730609 @default.
- W4283724369 creator A5009691684 @default.
- W4283724369 creator A5018817230 @default.
- W4283724369 creator A5021772665 @default.
- W4283724369 creator A5023674698 @default.
- W4283724369 creator A5027034891 @default.
- W4283724369 creator A5028557372 @default.
- W4283724369 creator A5034628620 @default.
- W4283724369 creator A5053797252 @default.
- W4283724369 creator A5062260473 @default.
- W4283724369 creator A5079663967 @default.
- W4283724369 creator A5080874221 @default.
- W4283724369 creator A5081844561 @default.
- W4283724369 creator A5086114240 @default.
- W4283724369 date "2022-06-30" @default.
- W4283724369 modified "2023-09-26" @default.
- W4283724369 title "Dietary adenosine 5’-monophosphate supplementation increases food intake and remodels energy expenditure in mice" @default.
- W4283724369 cites W1694069654 @default.
- W4283724369 cites W1900508696 @default.
- W4283724369 cites W1932664012 @default.
- W4283724369 cites W1969250137 @default.
- W4283724369 cites W2000016422 @default.
- W4283724369 cites W2003795680 @default.
- W4283724369 cites W2005946810 @default.
- W4283724369 cites W2027753197 @default.
- W4283724369 cites W2033401611 @default.
- W4283724369 cites W2037609985 @default.
- W4283724369 cites W2052609811 @default.
- W4283724369 cites W2057845450 @default.
- W4283724369 cites W2063574189 @default.
- W4283724369 cites W2069759343 @default.
- W4283724369 cites W2077355368 @default.
- W4283724369 cites W2079029423 @default.
- W4283724369 cites W2088986234 @default.
- W4283724369 cites W2090170281 @default.
- W4283724369 cites W2096842458 @default.
- W4283724369 cites W2097672374 @default.
- W4283724369 cites W2114821999 @default.
- W4283724369 cites W2123076274 @default.
- W4283724369 cites W2126570399 @default.
- W4283724369 cites W2135083192 @default.
- W4283724369 cites W2135345594 @default.
- W4283724369 cites W2162023168 @default.
- W4283724369 cites W2167372092 @default.
- W4283724369 cites W2414361303 @default.
- W4283724369 cites W2515072731 @default.
- W4283724369 cites W2752817656 @default.
- W4283724369 cites W2765987276 @default.
- W4283724369 cites W2784374391 @default.
- W4283724369 cites W2791052961 @default.
- W4283724369 cites W2794773483 @default.
- W4283724369 cites W2801767676 @default.
- W4283724369 cites W2900485910 @default.
- W4283724369 cites W2902907486 @default.
- W4283724369 cites W2904506548 @default.
- W4283724369 cites W2906628236 @default.
- W4283724369 cites W2957063887 @default.
- W4283724369 cites W2958946453 @default.
- W4283724369 cites W2964982895 @default.
- W4283724369 cites W2980456360 @default.
- W4283724369 cites W2982576498 @default.
- W4283724369 cites W3039911325 @default.
- W4283724369 cites W3081636175 @default.
- W4283724369 cites W3082473729 @default.
- W4283724369 cites W3097526205 @default.
- W4283724369 cites W3113887347 @default.
- W4283724369 cites W4231961754 @default.
- W4283724369 cites W4235463792 @default.
- W4283724369 doi "https://doi.org/10.29219/fnr.v66.7680" @default.
- W4283724369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35844957" @default.
- W4283724369 hasPublicationYear "2022" @default.
- W4283724369 type Work @default.
- W4283724369 citedByCount "0" @default.
- W4283724369 crossrefType "journal-article" @default.
- W4283724369 hasAuthorship W4283724369A5000730609 @default.
- W4283724369 hasAuthorship W4283724369A5009691684 @default.
- W4283724369 hasAuthorship W4283724369A5018817230 @default.
- W4283724369 hasAuthorship W4283724369A5021772665 @default.
- W4283724369 hasAuthorship W4283724369A5023674698 @default.
- W4283724369 hasAuthorship W4283724369A5027034891 @default.
- W4283724369 hasAuthorship W4283724369A5028557372 @default.
- W4283724369 hasAuthorship W4283724369A5034628620 @default.
- W4283724369 hasAuthorship W4283724369A5053797252 @default.
- W4283724369 hasAuthorship W4283724369A5062260473 @default.
- W4283724369 hasAuthorship W4283724369A5079663967 @default.
- W4283724369 hasAuthorship W4283724369A5080874221 @default.
- W4283724369 hasAuthorship W4283724369A5081844561 @default.
- W4283724369 hasAuthorship W4283724369A5086114240 @default.
- W4283724369 hasBestOaLocation W42837243691 @default.
- W4283724369 hasConcept C126322002 @default.
- W4283724369 hasConcept C134018914 @default.
- W4283724369 hasConcept C140985366 @default.
- W4283724369 hasConcept C151279926 @default.
- W4283724369 hasConcept C151955695 @default.
- W4283724369 hasConcept C171089720 @default.
- W4283724369 hasConcept C2776991684 @default.
- W4283724369 hasConcept C2779876172 @default.
- W4283724369 hasConcept C2780642333 @default.