Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283730149> ?p ?o ?g. }
- W4283730149 abstract "Chronic insomnia disorder (CID) is a highly prevalent sleep disorder, which influences people's daily life and is even life threatening. However, whether the resting-state regional homogeneity (ReHo) of disrupted brain regions in CID can be reshaped to normal after treatment remains unclear.A novel intervention real-time functional magnetic resonance imaging neurofeedback (rtfMRI-NF) was used to train 28 CID patients to regulate the activity of the left amygdala for three sessions in 6 weeks. The ReHo methodology was adopted to explore its role on resting-state fMRI data, which were collected before and after training. Moreover, the relationships between changes of clinical variables and ReHo value of altered regions were determined.Results showed that the bilateral dorsal medial pre-frontal cortex, supplementary motor area (SMA), and left dorsal lateral pre-frontal cortex had decreased ReHo values, whereas the bilateral cerebellum anterior lobe (CAL) had increased ReHo values after training. Some clinical scores markedly decreased, including Pittsburgh Sleep Quality Index, Insomnia Severity Index, Beck Depression Inventory, and Hamilton Anxiety Scale (HAMA). Additionally, the ReHo values of the left CAL were positively correlated with the change in the Hamilton depression scale score, and a remarkable positive correlation was found between the ReHo values of the right SMA and the HAMA score.Our study provided an objective evidence that amygdala-based rtfMRI-NF training could reshape abnormal ReHo and improve sleep in patients with CID. The improved ReHo in CID provides insights into the neurobiological mechanism for the effectiveness of this intervention. However, larger double-blinded sham-controlled trials are needed to confirm our results from this initial study." @default.
- W4283730149 created "2022-07-01" @default.
- W4283730149 creator A5003724939 @default.
- W4283730149 creator A5004356931 @default.
- W4283730149 creator A5005245031 @default.
- W4283730149 creator A5007980266 @default.
- W4283730149 creator A5010483436 @default.
- W4283730149 creator A5016035817 @default.
- W4283730149 creator A5016731632 @default.
- W4283730149 creator A5017056113 @default.
- W4283730149 creator A5018209087 @default.
- W4283730149 creator A5020240685 @default.
- W4283730149 creator A5026053703 @default.
- W4283730149 creator A5027297021 @default.
- W4283730149 creator A5029180269 @default.
- W4283730149 creator A5036031567 @default.
- W4283730149 creator A5046109344 @default.
- W4283730149 creator A5046131968 @default.
- W4283730149 creator A5052600804 @default.
- W4283730149 creator A5079353905 @default.
- W4283730149 date "2022-06-30" @default.
- W4283730149 modified "2023-09-25" @default.
- W4283730149 title "Improved Regional Homogeneity in Chronic Insomnia Disorder After Amygdala-Based Real-Time fMRI Neurofeedback Training" @default.
- W4283730149 cites W1526225438 @default.
- W4283730149 cites W1985408596 @default.
- W4283730149 cites W2000681816 @default.
- W4283730149 cites W2006023779 @default.
- W4283730149 cites W2007213925 @default.
- W4283730149 cites W2011695670 @default.
- W4283730149 cites W2019531859 @default.
- W4283730149 cites W2024602020 @default.
- W4283730149 cites W2035788517 @default.
- W4283730149 cites W2047560111 @default.
- W4283730149 cites W2061404494 @default.
- W4283730149 cites W2072500831 @default.
- W4283730149 cites W2072833030 @default.
- W4283730149 cites W2080054778 @default.
- W4283730149 cites W2081297347 @default.
- W4283730149 cites W2082538973 @default.
- W4283730149 cites W2082850379 @default.
- W4283730149 cites W2088955598 @default.
- W4283730149 cites W2090981517 @default.
- W4283730149 cites W2125820781 @default.
- W4283730149 cites W2144565788 @default.
- W4283730149 cites W2151487996 @default.
- W4283730149 cites W2171640896 @default.
- W4283730149 cites W2220908208 @default.
- W4283730149 cites W2288359005 @default.
- W4283730149 cites W2335356418 @default.
- W4283730149 cites W2337323496 @default.
- W4283730149 cites W2402651274 @default.
- W4283730149 cites W2409489891 @default.
- W4283730149 cites W2517888883 @default.
- W4283730149 cites W2589204232 @default.
- W4283730149 cites W2595823169 @default.
- W4283730149 cites W2607313129 @default.
- W4283730149 cites W2622293088 @default.
- W4283730149 cites W2702438521 @default.
- W4283730149 cites W2759970814 @default.
- W4283730149 cites W2761618777 @default.
- W4283730149 cites W2763386556 @default.
- W4283730149 cites W2765813173 @default.
- W4283730149 cites W2793548973 @default.
- W4283730149 cites W2793576554 @default.
- W4283730149 cites W2794423579 @default.
- W4283730149 cites W2802861806 @default.
- W4283730149 cites W2803274756 @default.
- W4283730149 cites W2804632146 @default.
- W4283730149 cites W2807404538 @default.
- W4283730149 cites W2907361360 @default.
- W4283730149 cites W2912850932 @default.
- W4283730149 cites W2966871651 @default.
- W4283730149 cites W2996555025 @default.
- W4283730149 cites W3001838957 @default.
- W4283730149 cites W3008300891 @default.
- W4283730149 cites W3008669586 @default.
- W4283730149 cites W3037468593 @default.
- W4283730149 cites W3082526819 @default.
- W4283730149 cites W3106310344 @default.
- W4283730149 cites W3111036039 @default.
- W4283730149 cites W3122167269 @default.
- W4283730149 cites W3159938699 @default.
- W4283730149 cites W3206235436 @default.
- W4283730149 cites W3206291437 @default.
- W4283730149 cites W3214237254 @default.
- W4283730149 cites W42357488 @default.
- W4283730149 cites W4237924405 @default.
- W4283730149 doi "https://doi.org/10.3389/fpsyt.2022.863056" @default.
- W4283730149 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35845454" @default.
- W4283730149 hasPublicationYear "2022" @default.
- W4283730149 type Work @default.
- W4283730149 citedByCount "1" @default.
- W4283730149 countsByYear W42837301492023 @default.
- W4283730149 crossrefType "journal-article" @default.
- W4283730149 hasAuthorship W4283730149A5003724939 @default.
- W4283730149 hasAuthorship W4283730149A5004356931 @default.
- W4283730149 hasAuthorship W4283730149A5005245031 @default.
- W4283730149 hasAuthorship W4283730149A5007980266 @default.
- W4283730149 hasAuthorship W4283730149A5010483436 @default.
- W4283730149 hasAuthorship W4283730149A5016035817 @default.