Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283730812> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W4283730812 endingPage "377" @default.
- W4283730812 startingPage "372" @default.
- W4283730812 abstract "Abstract Antitumor activities of L-MTP-PE (Liposome entrapped myuramyl tripeptide phosphatidylethanolamine) in the combination treatment with chemo- or immune-therapeutic antitumor agents against various syngeneic tumors were tested. Against Meth A fibrosarcoma solid tumor system, L-MTP-PE showed slight but statistically significant elongation of survival days against 5-FU monotherapy in spite of its non-effect on tumor growth, when combined with 5-FU. Against liver metastasis model of M5076 carcinoma, L-MTP-PE showed a tendency of elongation of survival days by its single drug treatment, however, elongation with statistical significance was observed in the combination treatment with 5-FU in comparison with control group. These data suggest that L-MTP-PE seems to elongate the survival days of the solid tumor bearing mice and the liver metastasis model basically due to its saving effect on chemotherapeutic drug-induced immunosuppression. In the combination with an immunotherapeutic agent in mice, TNF production induced by another biological response modifier OK-432 was potentiated when primed with L-MTP-PE. L-MTP-PE also potentiate the antitumor effect of OK-432 possibly through the enhanced production of TNF-α. Combination of L-MTP-PE and OK-432 is considered to be a candidate for a new treatment model for cancer." @default.
- W4283730812 created "2022-07-01" @default.
- W4283730812 creator A5017496507 @default.
- W4283730812 creator A5038065122 @default.
- W4283730812 date "2022-06-29" @default.
- W4283730812 modified "2023-09-24" @default.
- W4283730812 title "Effects of Liposome-Entrapped Muramyl Tripeptide Phosphatidylethanolamine (L-MTP-PE) on the Tumor Growth and Survival of Mice Bearing Syngeneic Tumor in Combination with a Chemotherapeutic or Immunomodulatory Agent" @default.
- W4283730812 cites W1496063422 @default.
- W4283730812 cites W1560442904 @default.
- W4283730812 cites W1931314445 @default.
- W4283730812 cites W1965786546 @default.
- W4283730812 cites W1981376615 @default.
- W4283730812 cites W1997696658 @default.
- W4283730812 cites W2000992025 @default.
- W4283730812 cites W2017898700 @default.
- W4283730812 cites W2038927253 @default.
- W4283730812 cites W2050521315 @default.
- W4283730812 cites W2058138047 @default.
- W4283730812 cites W2126880379 @default.
- W4283730812 cites W2152392662 @default.
- W4283730812 cites W2170605026 @default.
- W4283730812 cites W3202901824 @default.
- W4283730812 doi "https://doi.org/10.1055/a-1847-7312" @default.
- W4283730812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35767993" @default.
- W4283730812 hasPublicationYear "2022" @default.
- W4283730812 type Work @default.
- W4283730812 citedByCount "0" @default.
- W4283730812 crossrefType "journal-article" @default.
- W4283730812 hasAuthorship W4283730812A5017496507 @default.
- W4283730812 hasAuthorship W4283730812A5038065122 @default.
- W4283730812 hasConcept C121608353 @default.
- W4283730812 hasConcept C126322002 @default.
- W4283730812 hasConcept C142724271 @default.
- W4283730812 hasConcept C185592680 @default.
- W4283730812 hasConcept C203014093 @default.
- W4283730812 hasConcept C2776495794 @default.
- W4283730812 hasConcept C2776694085 @default.
- W4283730812 hasConcept C2776999253 @default.
- W4283730812 hasConcept C2779013556 @default.
- W4283730812 hasConcept C2781264782 @default.
- W4283730812 hasConcept C502942594 @default.
- W4283730812 hasConcept C71924100 @default.
- W4283730812 hasConcept C8891405 @default.
- W4283730812 hasConcept C98274493 @default.
- W4283730812 hasConceptScore W4283730812C121608353 @default.
- W4283730812 hasConceptScore W4283730812C126322002 @default.
- W4283730812 hasConceptScore W4283730812C142724271 @default.
- W4283730812 hasConceptScore W4283730812C185592680 @default.
- W4283730812 hasConceptScore W4283730812C203014093 @default.
- W4283730812 hasConceptScore W4283730812C2776495794 @default.
- W4283730812 hasConceptScore W4283730812C2776694085 @default.
- W4283730812 hasConceptScore W4283730812C2776999253 @default.
- W4283730812 hasConceptScore W4283730812C2779013556 @default.
- W4283730812 hasConceptScore W4283730812C2781264782 @default.
- W4283730812 hasConceptScore W4283730812C502942594 @default.
- W4283730812 hasConceptScore W4283730812C71924100 @default.
- W4283730812 hasConceptScore W4283730812C8891405 @default.
- W4283730812 hasConceptScore W4283730812C98274493 @default.
- W4283730812 hasIssue "07" @default.
- W4283730812 hasLocation W42837308121 @default.
- W4283730812 hasLocation W42837308122 @default.
- W4283730812 hasOpenAccess W4283730812 @default.
- W4283730812 hasPrimaryLocation W42837308121 @default.
- W4283730812 hasRelatedWork W1499339123 @default.
- W4283730812 hasRelatedWork W1975859778 @default.
- W4283730812 hasRelatedWork W2057730598 @default.
- W4283730812 hasRelatedWork W2063218918 @default.
- W4283730812 hasRelatedWork W2154708791 @default.
- W4283730812 hasRelatedWork W2898196535 @default.
- W4283730812 hasRelatedWork W3173207637 @default.
- W4283730812 hasRelatedWork W4283771460 @default.
- W4283730812 hasRelatedWork W4304116770 @default.
- W4283730812 hasRelatedWork W4361261034 @default.
- W4283730812 hasVolume "72" @default.
- W4283730812 isParatext "false" @default.
- W4283730812 isRetracted "false" @default.
- W4283730812 workType "article" @default.