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• W4283731082 abstract "Changes in the composition of the gut microbiota are associated with many human diseases. So far, however, we have failed to define homeostasis or dysbiosis by the presence or absence of specific microbial species. The composition and function of the adult gut microbiota is governed by diet and host factors that regulate and direct microbial growth. The host delivers oxygen and nitrate to the lumen of the small intestine, which selects for bacteria that use respiration for energy production. In the colon, by contrast, the host limits the availability of oxygen and nitrate, which results in a bacterial community that specializes in fermentation for growth. Although diet influences microbiota composition, a poor diet weakens host control mechanisms that regulate the microbiota. Hence, quantifying host parameters that control microbial growth could help define homeostasis or dysbiosis and could offer alternative strategies to remediate dysbiosis." @default.
• W4283731082 created "2022-07-01" @default.
• W4283731082 creator A5052459903 @default.
• W4283731082 creator A5054787075 @default.
• W4283731082 creator A5055198853 @default.
• W4283731082 date "2022-07-01" @default.
• W4283731082 modified "2023-10-15" @default.
• W4283731082 title "The microbiome and gut homeostasis" @default.
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