FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283746990> ?p ?o ?g. }

• W4283746990 abstract "Abstract Study question How does the overall quality of life (QoL) of infertile women and men evolve during the diagnostic workup and during intrauterine insemination (IUI)? Summary answer The diagnostic workup affects the overall QoL of neither women nor men but both partner’s QoL is diminished by the time of their third IUI. What is known already Overall quality of life (QoL) is increasingly acknowledged as the ultimate measure of health care quality. The WHO defines ‘overall QoL’ as an individual’s perception of their position in life in relation to their context, goals, expectations, standards and concerns. Infertility threatens the life goal of becoming parents. Value preference studies concluded that cost analyses should consider a decrement in women’s QoL for ‘being infertile with the desire for a child’. The short-term QoL costs or benefits of the fertility clinic trajectory, before potentially achieving the long-term benefit of a live birth, have yet to be examined. Study design, size, duration Two cohorts consulting a Belgian fertility clinic were studied longitudinally. Cohort 1 (C1) included 36 women and their partners (response rate 54%), who were surveyed before their first consultation (T1) and three months later, towards the end of their diagnostic workup (T2; 2017-2019). Cohort 2 (C2) included 23 women and their partners (response rate 64%), who were surveyed during their diagnostic workup (T1) and at the time of their third IUI (T2; 2020-2021). Participants/materials, setting, methods Dutch- or English-speaking heterosexual couples first consulting a fertility clinic were eligible. Overall QoL was assessed with the valid and reliable linear analogue scale (LAS; range: 1-100; the higher, the better QoL; Moons et al., Eur J Cardiovasc Prev Rehabil, 2006). Paired samples t-tests assessed the evolution in the overall QoL of women and of men. Linear models examined whether already being parents and male factor infertility affected change scores. Main results and the role of chance Women and men of both cohorts were on average in their early thirties and couples had tried to conceive naturally for, on average, 19 (C1) and 16 (C2) months. Most individuals (65.4% in C1; 87% in C2) did not yet parent a child. A considerate proportion of couples had been diagnosed with (amongst others) male factor infertility (34.6% in C1; 26.0% in C2). The diagnostic workup did not affect the overall QoL of women (T1: 78.8±8.1 vs. T2: 75.8±9.7, p = 0.147) or men (T1: 80.8±7.9 vs. T2: 79.2±8.7, p = 0.206). The evolution in overall QoL throughout the diagnostic workup did not depend on parenthood status or male factor infertility (p &gt; 0.05). By the time of their third IUI, women’s overall QoL had diminished (T1: 80.9±9.9 vs. T2: 74.0±15.0, p = 0.018). This evolution was not affected by parenthood status or male factor infertility (p &gt; 0.05). Similarly, men’s overall QoL had diminished by the time of their third IUI (T1: 82.0±7.2 vs. T2: 78.1±9.6, p = 0.042). This reduction in men’s QoL was not affected by parenthood status (p = 0.759) but was especially observed (p = 0.028) among men without male factor infertility (T1: 82.9±7.9 vs. T2: 77.0±11.0, p = 0.008). Limitations, reasons for caution The rather small sample sizes were sufficient for examining the effect on QoL of time and two potential determinants (parenthood status, male factor infertility) according to the rule of thumb of including minimally five individuals per variable. Recruitment is still ongoing to increase the power of these cohort studies. Wider implications of the findings Fertility nurses/midwives should inform couples pursuing their life goal of parenthood that the fertility clinic trajectory will require short-term sacrifices. The diagnostic workup affects the overall QoL of neither women nor men, but both partner’s overall QoL is slightly diminished by the time of their third unsuccessful intrauterine insemination. Trial registration number not applicable" @default.
• W4283746990 created "2022-07-02" @default.
• W4283746990 creator A5017458344 @default.
• W4283746990 creator A5024986861 @default.
• W4283746990 creator A5048507794 @default.
• W4283746990 creator A5049163835 @default.
• W4283746990 creator A5062495887 @default.
• W4283746990 creator A5074400005 @default.
• W4283746990 date "2022-06-29" @default.
• W4283746990 modified "2023-09-26" @default.
• W4283746990 title "O-158 The evolution of the quality of life of women and men during the fertility clinic trajectory: a longitudinal survey" @default.
• W4283746990 doi "https://doi.org/10.1093/humrep/deac105.064" @default.
• W4283746990 hasPublicationYear "2022" @default.
• W4283746990 type Work @default.
• W4283746990 citedByCount "0" @default.
• W4283746990 crossrefType "journal-article" @default.
• W4283746990 hasAuthorship W4283746990A5017458344 @default.
• W4283746990 hasAuthorship W4283746990A5024986861 @default.
• W4283746990 hasAuthorship W4283746990A5048507794 @default.
• W4283746990 hasAuthorship W4283746990A5049163835 @default.
• W4283746990 hasAuthorship W4283746990A5062495887 @default.
• W4283746990 hasAuthorship W4283746990A5074400005 @default.
• W4283746990 hasBestOaLocation W42837469901 @default.
• W4283746990 hasConcept C126322002 @default.
• W4283746990 hasConcept C142724271 @default.
• W4283746990 hasConcept C144024400 @default.
• W4283746990 hasConcept C149923435 @default.
• W4283746990 hasConcept C151730666 @default.
• W4283746990 hasConcept C159110408 @default.
• W4283746990 hasConcept C201903717 @default.
• W4283746990 hasConcept C204411529 @default.
• W4283746990 hasConcept C2777688143 @default.
• W4283746990 hasConcept C2779234561 @default.
• W4283746990 hasConcept C2779343474 @default.
• W4283746990 hasConcept C2779951463 @default.
• W4283746990 hasConcept C2908647359 @default.
• W4283746990 hasConcept C29456083 @default.
• W4283746990 hasConcept C512399662 @default.
• W4283746990 hasConcept C518429986 @default.
• W4283746990 hasConcept C54355233 @default.
• W4283746990 hasConcept C71924100 @default.
• W4283746990 hasConcept C72563966 @default.
• W4283746990 hasConcept C86803240 @default.
• W4283746990 hasConcept C99454951 @default.
• W4283746990 hasConceptScore W4283746990C126322002 @default.
• W4283746990 hasConceptScore W4283746990C142724271 @default.
• W4283746990 hasConceptScore W4283746990C144024400 @default.
• W4283746990 hasConceptScore W4283746990C149923435 @default.
• W4283746990 hasConceptScore W4283746990C151730666 @default.
• W4283746990 hasConceptScore W4283746990C159110408 @default.
• W4283746990 hasConceptScore W4283746990C201903717 @default.
• W4283746990 hasConceptScore W4283746990C204411529 @default.
• W4283746990 hasConceptScore W4283746990C2777688143 @default.
• W4283746990 hasConceptScore W4283746990C2779234561 @default.
• W4283746990 hasConceptScore W4283746990C2779343474 @default.
• W4283746990 hasConceptScore W4283746990C2779951463 @default.
• W4283746990 hasConceptScore W4283746990C2908647359 @default.
• W4283746990 hasConceptScore W4283746990C29456083 @default.
• W4283746990 hasConceptScore W4283746990C512399662 @default.
• W4283746990 hasConceptScore W4283746990C518429986 @default.
• W4283746990 hasConceptScore W4283746990C54355233 @default.
• W4283746990 hasConceptScore W4283746990C71924100 @default.
• W4283746990 hasConceptScore W4283746990C72563966 @default.
• W4283746990 hasConceptScore W4283746990C86803240 @default.
• W4283746990 hasConceptScore W4283746990C99454951 @default.
• W4283746990 hasIssue "Supplement_1" @default.
• W4283746990 hasLocation W42837469901 @default.
• W4283746990 hasOpenAccess W4283746990 @default.
• W4283746990 hasPrimaryLocation W42837469901 @default.
• W4283746990 hasRelatedWork W1958794492 @default.
• W4283746990 hasRelatedWork W1994184043 @default.
• W4283746990 hasRelatedWork W2022763683 @default.
• W4283746990 hasRelatedWork W2285688334 @default.
• W4283746990 hasRelatedWork W2939531057 @default.
• W4283746990 hasRelatedWork W3092748573 @default.
• W4283746990 hasRelatedWork W3110791761 @default.
• W4283746990 hasRelatedWork W4245955931 @default.
• W4283746990 hasRelatedWork W4283743330 @default.
• W4283746990 hasRelatedWork W47308221 @default.
• W4283746990 hasVolume "37" @default.
• W4283746990 isParatext "false" @default.
• W4283746990 isRetracted "false" @default.
• W4283746990 workType "article" @default.