Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283785803> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W4283785803 abstract "Abstract Lepidopteran larvae have both thoracic legs and abdominal prolegs, yet it is unclear whether these are serial homologs. We examined the role of three Hox genes in proleg development in Bicyclus anynana butterflies using CRISPR-Cas9 and discovered that under a partial segment abdominal-A ( abd-A ) knockout, both types of appendages can develop in the same segment, arguing for prolegs being a novel trait, not a leg serial homolog. We also discover that specificity protein (sp) genes do not co-localize with Distal-less (Dll) in prolegs, as they do in legs, and that the proleg gene-regulatory network (GRN) mostly resembles the head-horn GRN, another novel trait in the lepidoptera. We propose that larval prolegs evolved from the co-option of a partial limb GRN into novel embryonic coordinates in the abdomen. One-Sentence Summary The chubby legs of caterpillars are evolutionary innovations" @default.
- W4283785803 created "2022-07-04" @default.
- W4283785803 creator A5028499160 @default.
- W4283785803 creator A5045095024 @default.
- W4283785803 creator A5055163415 @default.
- W4283785803 creator A5070471374 @default.
- W4283785803 date "2022-07-02" @default.
- W4283785803 modified "2023-10-14" @default.
- W4283785803 title "Lepidopteran prolegs are novel traits, not leg homologs" @default.
- W4283785803 cites W1978859038 @default.
- W4283785803 cites W1980116334 @default.
- W4283785803 cites W1980312395 @default.
- W4283785803 cites W1991789141 @default.
- W4283785803 cites W1997908833 @default.
- W4283785803 cites W1998840633 @default.
- W4283785803 cites W2007954779 @default.
- W4283785803 cites W2011657487 @default.
- W4283785803 cites W2017070675 @default.
- W4283785803 cites W2018425617 @default.
- W4283785803 cites W2020522405 @default.
- W4283785803 cites W2048795914 @default.
- W4283785803 cites W2050584607 @default.
- W4283785803 cites W2109788546 @default.
- W4283785803 cites W2111202552 @default.
- W4283785803 cites W2119306344 @default.
- W4283785803 cites W2154240765 @default.
- W4283785803 cites W2179438025 @default.
- W4283785803 cites W2510875395 @default.
- W4283785803 cites W2581034194 @default.
- W4283785803 cites W2623519603 @default.
- W4283785803 cites W2924532115 @default.
- W4283785803 cites W2936001650 @default.
- W4283785803 cites W2964849163 @default.
- W4283785803 cites W2980539212 @default.
- W4283785803 cites W2990026973 @default.
- W4283785803 cites W2991421160 @default.
- W4283785803 cites W2992190215 @default.
- W4283785803 cites W3031118440 @default.
- W4283785803 cites W3095034229 @default.
- W4283785803 cites W3095435683 @default.
- W4283785803 cites W4213213129 @default.
- W4283785803 cites W48498455 @default.
- W4283785803 doi "https://doi.org/10.1101/2022.06.30.498371" @default.
- W4283785803 hasPublicationYear "2022" @default.
- W4283785803 type Work @default.
- W4283785803 citedByCount "2" @default.
- W4283785803 crossrefType "posted-content" @default.
- W4283785803 hasAuthorship W4283785803A5028499160 @default.
- W4283785803 hasAuthorship W4283785803A5045095024 @default.
- W4283785803 hasAuthorship W4283785803A5055163415 @default.
- W4283785803 hasAuthorship W4283785803A5070471374 @default.
- W4283785803 hasBestOaLocation W42837858031 @default.
- W4283785803 hasConcept C104317684 @default.
- W4283785803 hasConcept C105702510 @default.
- W4283785803 hasConcept C111039654 @default.
- W4283785803 hasConcept C177756618 @default.
- W4283785803 hasConcept C18903297 @default.
- W4283785803 hasConcept C41451933 @default.
- W4283785803 hasConcept C54355233 @default.
- W4283785803 hasConcept C78458016 @default.
- W4283785803 hasConcept C86339819 @default.
- W4283785803 hasConcept C86803240 @default.
- W4283785803 hasConcept C98108389 @default.
- W4283785803 hasConceptScore W4283785803C104317684 @default.
- W4283785803 hasConceptScore W4283785803C105702510 @default.
- W4283785803 hasConceptScore W4283785803C111039654 @default.
- W4283785803 hasConceptScore W4283785803C177756618 @default.
- W4283785803 hasConceptScore W4283785803C18903297 @default.
- W4283785803 hasConceptScore W4283785803C41451933 @default.
- W4283785803 hasConceptScore W4283785803C54355233 @default.
- W4283785803 hasConceptScore W4283785803C78458016 @default.
- W4283785803 hasConceptScore W4283785803C86339819 @default.
- W4283785803 hasConceptScore W4283785803C86803240 @default.
- W4283785803 hasConceptScore W4283785803C98108389 @default.
- W4283785803 hasLocation W42837858031 @default.
- W4283785803 hasOpenAccess W4283785803 @default.
- W4283785803 hasPrimaryLocation W42837858031 @default.
- W4283785803 hasRelatedWork W1921205358 @default.
- W4283785803 hasRelatedWork W2009232589 @default.
- W4283785803 hasRelatedWork W2068721136 @default.
- W4283785803 hasRelatedWork W2117675834 @default.
- W4283785803 hasRelatedWork W2126925403 @default.
- W4283785803 hasRelatedWork W2161598420 @default.
- W4283785803 hasRelatedWork W2349719042 @default.
- W4283785803 hasRelatedWork W2359087469 @default.
- W4283785803 hasRelatedWork W2419154145 @default.
- W4283785803 hasRelatedWork W4289745310 @default.
- W4283785803 isParatext "false" @default.
- W4283785803 isRetracted "false" @default.
- W4283785803 workType "article" @default.