Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283787596> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W4283787596 endingPage "73" @default.
- W4283787596 startingPage "69" @default.
- W4283787596 abstract "Fibrocystic change is the most common benign lesion in breasts of a woman in her reproductive age. It is an outcome of estrogen excess due to sex hormone imbalance. Cyclical pain as the most common symptom worsens life quality, compels patient to seek health care support continuously, and imposes large amounts of expense to both patient and health system. Current study aims to evaluate effects of N-acetyl cysteine on decreasing pain and changes in plasma biochemistry.A total of 64 eligible women participated in this double-blinded randomized controlled trial. They were between 18 and 40 years. Participants were randomly allocated into oral N-acetyl cysteine and placebo receivers. Intervention and follow-up lasted for, respectively, a 12-week drugs-on and 12-month drugs-off period. Visual analog scaling was applied to measure severity of pain. Peripheral venous plasma was extracted and compared for inflammatory parameters including high-sensitivity C-reactive protein, total antioxidant capacity, malondialdehyde, total plasma glutathione, lipid profile, and fasting blood sugar.Oral N-acetyl cysteine significantly decreased feeling of cyclical mastalgia (P < .01) after 12 weeks of consumption. In addition to lowering of plasma level of high-sensitivity C-reactive protein (P = .008), total plasma glutathione significantly increased (P = .02) among N-acetyl cysteine receivers. No change in lipid profile and insulin sensitivity was seen.N-Acetyl cysteine could mitigate cyclical mastalgia. Inflammation as a considered reason for cyclical mastalgia also was halted by N-acetyl cysteine consumption." @default.
- W4283787596 created "2022-07-04" @default.
- W4283787596 creator A5011710574 @default.
- W4283787596 creator A5024719490 @default.
- W4283787596 creator A5031200734 @default.
- W4283787596 creator A5048753783 @default.
- W4283787596 creator A5061773224 @default.
- W4283787596 creator A5062643990 @default.
- W4283787596 creator A5079146770 @default.
- W4283787596 date "2022-10-01" @default.
- W4283787596 modified "2023-10-14" @default.
- W4283787596 title "Effects of oral N-acetyl cysteine on pain and plasma biochemical parameters in fibrocystic breast disorder: A randomized controlled trial" @default.
- W4283787596 cites W1653894056 @default.
- W4283787596 cites W1966308856 @default.
- W4283787596 cites W2008023699 @default.
- W4283787596 cites W2048967035 @default.
- W4283787596 cites W2109743845 @default.
- W4283787596 cites W2117881483 @default.
- W4283787596 cites W2132928232 @default.
- W4283787596 cites W2151272921 @default.
- W4283787596 cites W2151581598 @default.
- W4283787596 cites W2191713228 @default.
- W4283787596 cites W2504383647 @default.
- W4283787596 cites W2590397000 @default.
- W4283787596 cites W2785731909 @default.
- W4283787596 cites W2792716492 @default.
- W4283787596 cites W2906387696 @default.
- W4283787596 cites W2911468624 @default.
- W4283787596 cites W2958444722 @default.
- W4283787596 cites W2970306476 @default.
- W4283787596 cites W2972327649 @default.
- W4283787596 cites W3099430603 @default.
- W4283787596 cites W3165017500 @default.
- W4283787596 cites W3035924862 @default.
- W4283787596 doi "https://doi.org/10.1016/j.sopen.2022.06.006" @default.
- W4283787596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36016767" @default.
- W4283787596 hasPublicationYear "2022" @default.
- W4283787596 type Work @default.
- W4283787596 citedByCount "1" @default.
- W4283787596 countsByYear W42837875962022 @default.
- W4283787596 crossrefType "journal-article" @default.
- W4283787596 hasAuthorship W4283787596A5011710574 @default.
- W4283787596 hasAuthorship W4283787596A5024719490 @default.
- W4283787596 hasAuthorship W4283787596A5031200734 @default.
- W4283787596 hasAuthorship W4283787596A5048753783 @default.
- W4283787596 hasAuthorship W4283787596A5061773224 @default.
- W4283787596 hasAuthorship W4283787596A5062643990 @default.
- W4283787596 hasAuthorship W4283787596A5079146770 @default.
- W4283787596 hasBestOaLocation W42837875961 @default.
- W4283787596 hasConcept C126322002 @default.
- W4283787596 hasConcept C134018914 @default.
- W4283787596 hasConcept C142724271 @default.
- W4283787596 hasConcept C168563851 @default.
- W4283787596 hasConcept C181199279 @default.
- W4283787596 hasConcept C185592680 @default.
- W4283787596 hasConcept C204787440 @default.
- W4283787596 hasConcept C27081682 @default.
- W4283787596 hasConcept C538909803 @default.
- W4283787596 hasConcept C55493867 @default.
- W4283787596 hasConcept C71924100 @default.
- W4283787596 hasConcept C90924648 @default.
- W4283787596 hasConceptScore W4283787596C126322002 @default.
- W4283787596 hasConceptScore W4283787596C134018914 @default.
- W4283787596 hasConceptScore W4283787596C142724271 @default.
- W4283787596 hasConceptScore W4283787596C168563851 @default.
- W4283787596 hasConceptScore W4283787596C181199279 @default.
- W4283787596 hasConceptScore W4283787596C185592680 @default.
- W4283787596 hasConceptScore W4283787596C204787440 @default.
- W4283787596 hasConceptScore W4283787596C27081682 @default.
- W4283787596 hasConceptScore W4283787596C538909803 @default.
- W4283787596 hasConceptScore W4283787596C55493867 @default.
- W4283787596 hasConceptScore W4283787596C71924100 @default.
- W4283787596 hasConceptScore W4283787596C90924648 @default.
- W4283787596 hasFunder F4320322316 @default.
- W4283787596 hasFunder F4320328103 @default.
- W4283787596 hasLocation W42837875961 @default.
- W4283787596 hasLocation W42837875962 @default.
- W4283787596 hasLocation W42837875963 @default.
- W4283787596 hasOpenAccess W4283787596 @default.
- W4283787596 hasPrimaryLocation W42837875961 @default.
- W4283787596 hasRelatedWork W1966504330 @default.
- W4283787596 hasRelatedWork W1966775726 @default.
- W4283787596 hasRelatedWork W1979139803 @default.
- W4283787596 hasRelatedWork W1991560548 @default.
- W4283787596 hasRelatedWork W2030889776 @default.
- W4283787596 hasRelatedWork W2037631372 @default.
- W4283787596 hasRelatedWork W2040058909 @default.
- W4283787596 hasRelatedWork W2132898409 @default.
- W4283787596 hasRelatedWork W2748952813 @default.
- W4283787596 hasRelatedWork W4249176446 @default.
- W4283787596 hasVolume "10" @default.
- W4283787596 isParatext "false" @default.
- W4283787596 isRetracted "false" @default.
- W4283787596 workType "article" @default.