Matches in SemOpenAlex for { <https://semopenalex.org/work/W4283795914> ?p ?o ?g. }
- W4283795914 endingPage "884" @default.
- W4283795914 startingPage "884" @default.
- W4283795914 abstract "Background and Objectives: Cancer and coronary artery disease (CAD) often coexist. Compared to quantitative coronary angiography (QCA), fractional flow reserve (FFR) has emerged as a more reliable method of identifying significant coronary stenoses. We aimed to assess the specific management, safety and outcomes of FFR-guided percutaneous coronary intervention (PCI) in cancer patients with stable CAD. Materials and Methods: FFR was used to assess cancer patients that underwent coronary angiography for stable CAD between September 2008 and May 2016, and were found to have ≥50% stenosis by QCA. Patients with lesions with an FFR > 0.75 received medical therapy alone, while those with FFR ≤ 0.75 were revascularized. Procedure-related complications, all-cause mortality, nonfatal myocardial infarction, or urgent revascularizations were analyzed. Results: Fifty-seven patients with stable CAD underwent FFR on 57 lesions. Out of 31 patients with ≥70% stenosis as measured by QCA, 14 (45.1%) had an FFR ≥ 0.75 and lesions were reclassified as moderate and did not receive PCI nor DAPT. Out of 26 patients with <70% stenosis as measured by QCA, 6 (23%) had an FFR < 0.75 and were reclassified as severe and were treated with PCI and associated DAPT. No periprocedural complications, urgent revascularization, acute coronary syndromes, or cardiovascular deaths were noted. There was a 22.8% mortality at 1 year, all cancer related. Patients who received a stent by FFR assessment showed a significant association with decreased risk of all-cause death (HR: 0.37, 95% CI 0.15−0.90, p = 0.03). Conclusions: Further studies are needed to define the optimal therapeutic approach for cancer patients with CAD. Using an FFR cut-off point of 0.75 to guide PCI translates into fewer interventions and can facilitate cancer care. There was an overall reduction in mortality in patients that received a stent, suggesting increased resilience to cancer therapy and progression." @default.
- W4283795914 created "2022-07-05" @default.
- W4283795914 creator A5001121946 @default.
- W4283795914 creator A5008724119 @default.
- W4283795914 creator A5008839207 @default.
- W4283795914 creator A5016493985 @default.
- W4283795914 creator A5024723627 @default.
- W4283795914 creator A5026092252 @default.
- W4283795914 creator A5032469411 @default.
- W4283795914 creator A5032654535 @default.
- W4283795914 creator A5036321409 @default.
- W4283795914 creator A5047797118 @default.
- W4283795914 creator A5049475717 @default.
- W4283795914 creator A5060233241 @default.
- W4283795914 creator A5066053823 @default.
- W4283795914 creator A5066436537 @default.
- W4283795914 creator A5068791121 @default.
- W4283795914 creator A5069253754 @default.
- W4283795914 creator A5075120074 @default.
- W4283795914 creator A5075379279 @default.
- W4283795914 creator A5081033881 @default.
- W4283795914 creator A5085199459 @default.
- W4283795914 creator A5086612308 @default.
- W4283795914 date "2022-07-01" @default.
- W4283795914 modified "2023-10-18" @default.
- W4283795914 title "Reclassification of Treatment Strategy with Fractional Flow Reserve in Cancer Patients with Coronary Artery Disease" @default.
- W4283795914 cites W147178430 @default.
- W4283795914 cites W2031438938 @default.
- W4283795914 cites W2103130362 @default.
- W4283795914 cites W2112534549 @default.
- W4283795914 cites W2133924558 @default.
- W4283795914 cites W2150801605 @default.
- W4283795914 cites W2166538393 @default.
- W4283795914 cites W2176144588 @default.
- W4283795914 cites W2239623475 @default.
- W4283795914 cites W2320707747 @default.
- W4283795914 cites W2417630380 @default.
- W4283795914 cites W2508848908 @default.
- W4283795914 cites W2551730582 @default.
- W4283795914 cites W2621775924 @default.
- W4283795914 cites W2795350877 @default.
- W4283795914 cites W2886250908 @default.
- W4283795914 cites W2900496554 @default.
- W4283795914 doi "https://doi.org/10.3390/medicina58070884" @default.
- W4283795914 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35888603" @default.
- W4283795914 hasPublicationYear "2022" @default.
- W4283795914 type Work @default.
- W4283795914 citedByCount "1" @default.
- W4283795914 countsByYear W42837959142023 @default.
- W4283795914 crossrefType "journal-article" @default.
- W4283795914 hasAuthorship W4283795914A5001121946 @default.
- W4283795914 hasAuthorship W4283795914A5008724119 @default.
- W4283795914 hasAuthorship W4283795914A5008839207 @default.
- W4283795914 hasAuthorship W4283795914A5016493985 @default.
- W4283795914 hasAuthorship W4283795914A5024723627 @default.
- W4283795914 hasAuthorship W4283795914A5026092252 @default.
- W4283795914 hasAuthorship W4283795914A5032469411 @default.
- W4283795914 hasAuthorship W4283795914A5032654535 @default.
- W4283795914 hasAuthorship W4283795914A5036321409 @default.
- W4283795914 hasAuthorship W4283795914A5047797118 @default.
- W4283795914 hasAuthorship W4283795914A5049475717 @default.
- W4283795914 hasAuthorship W4283795914A5060233241 @default.
- W4283795914 hasAuthorship W4283795914A5066053823 @default.
- W4283795914 hasAuthorship W4283795914A5066436537 @default.
- W4283795914 hasAuthorship W4283795914A5068791121 @default.
- W4283795914 hasAuthorship W4283795914A5069253754 @default.
- W4283795914 hasAuthorship W4283795914A5075120074 @default.
- W4283795914 hasAuthorship W4283795914A5075379279 @default.
- W4283795914 hasAuthorship W4283795914A5081033881 @default.
- W4283795914 hasAuthorship W4283795914A5085199459 @default.
- W4283795914 hasAuthorship W4283795914A5086612308 @default.
- W4283795914 hasBestOaLocation W42837959141 @default.
- W4283795914 hasConcept C126322002 @default.
- W4283795914 hasConcept C126838900 @default.
- W4283795914 hasConcept C164705383 @default.
- W4283795914 hasConcept C2777987666 @default.
- W4283795914 hasConcept C2778213512 @default.
- W4283795914 hasConcept C2778583881 @default.
- W4283795914 hasConcept C2779464278 @default.
- W4283795914 hasConcept C2780007028 @default.
- W4283795914 hasConcept C2780400711 @default.
- W4283795914 hasConcept C3019004856 @default.
- W4283795914 hasConcept C45393284 @default.
- W4283795914 hasConcept C500558357 @default.
- W4283795914 hasConcept C71924100 @default.
- W4283795914 hasConceptScore W4283795914C126322002 @default.
- W4283795914 hasConceptScore W4283795914C126838900 @default.
- W4283795914 hasConceptScore W4283795914C164705383 @default.
- W4283795914 hasConceptScore W4283795914C2777987666 @default.
- W4283795914 hasConceptScore W4283795914C2778213512 @default.
- W4283795914 hasConceptScore W4283795914C2778583881 @default.
- W4283795914 hasConceptScore W4283795914C2779464278 @default.
- W4283795914 hasConceptScore W4283795914C2780007028 @default.
- W4283795914 hasConceptScore W4283795914C2780400711 @default.
- W4283795914 hasConceptScore W4283795914C3019004856 @default.
- W4283795914 hasConceptScore W4283795914C45393284 @default.
- W4283795914 hasConceptScore W4283795914C500558357 @default.
- W4283795914 hasConceptScore W4283795914C71924100 @default.