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• W4283826461 abstract "Abstract PURPOSE: To establish normal reference values of urine flow acceleration (Q acc ) in healthy children, as there is a lack of nomograms for normative reference values of Q acc by voided volumes in paediatric population so far. Q acc might be an early indicator of autonomic neuropathy in children and adolescents. METHODS: Data were retrospectively collected from healthy children who underwent uroflowmetry between 1990–­1992. Exclusion criteria were voided volume less than 20 mL, postvoid residual more than 15%, and signs of an overstretched bladder. Baseline characteristics and uroflowmetry parameters were collected from girls and boys based on their body surface measurements (<0.92 m 2 ; 0.92–1.42 m 2 ; and >1.42 m 2 ) . Voided volume, voiding time, time to maximum flow rate, maximum and average flow rates of urine were measured, Q acc was calculated. Postvoid bladder diameter was measured by ultrasonography and converted to volume. RESULTS: Uroflowmetry parameters of 208 children (≤18 years old, 45.2% girls, mean age 9.68 ± 3.09 years) who performed 404 micturition were analysed. Median voided volume was 130 [20–460] mL, median voiding time was 10 [3–56] sec, median time to Q max was 3 [1–14] sec, median Q ave was 11.7 [2.5–36.6] mL/sec, median Q max was 20.5 [5–50] mL/sec, median Q acc was 6 [0.81–25] mL/sec 2 , and median postvoid residual volume was 1.83 [0–38.62] mL in the total population. Q acc nomograms were given in centile forms for girls and boys separately which show an inversely proportional correlation between voided volumes. CONCLUSION: These are the first nomograms for normative reference values of Q acc in paediatric population (girls and boys separately) by voided volumes in centile forms. These may be useful to interpret abnormal Q acc values, and diagnose lower urinary tract diseases over a wide range of voided volumes." @default.
• W4283826461 created "2022-07-07" @default.
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• W4283826461 date "2022-07-06" @default.
• W4283826461 modified "2023-10-14" @default.
• W4283826461 title "Urine flow acceleration in healthy children: A retrospective cohort study" @default.
• W4283826461 doi "https://doi.org/10.21203/rs.3.rs-1785611/v1" @default.
• W4283826461 hasPublicationYear "2022" @default.
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