FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4284667457> ?p ?o ?g. }

• W4284667457 endingPage "913" @default.
• W4284667457 startingPage "893" @default.
• W4284667457 abstract "The mesoderm gives rise to several key morphological features of bilaterian animals including endoskeletal elements and the musculature. A number of regulatory genes involved in mesoderm and/or muscle formation (e.g., Brachyury (Bra), even-skipped (eve), Mox, myosin II heavy chain (mhc)) have been identified chiefly from chordates and the ecdysozoans Drosophila and Caenorhabditis elegans, but data for non-model protostomes, especially those belonging to the ecdysozoan sister clade, Lophotrochozoa (e.g., flatworms, annelids, mollusks), are only beginning to emerge. Within the lophotrochozoans, Mollusca constitutes the most speciose and diverse phylum. Interestingly, however, information on the morphological and molecular underpinnings of key ontogenetic processes such as mesoderm formation and myogenesis remains scarce even for prominent molluscan sublineages such as the bivalves. Here, we investigated myogenesis and developmental expression of Bra, eve, Mox, and mhc in the quagga mussel Dreissena rostriformis, an invasive freshwater bivalve and an emerging model in invertebrate evodevo. We found that all four genes are expressed during mesoderm formation, but some show additional, individual sites of expression during ontogeny. While Mox and mhc are involved in early myogenesis, eve is also expressed in the embryonic shell field and Bra is additionally present in the foregut. Comparative analysis suggests that Mox has an ancestral role in mesoderm and possibly muscle formation in bilaterians, while Bra and eve are conserved regulators of mesoderm development of nephrozoans (protostomes and deuterostomes). The fully developed Dreissena veliger larva shows a highly complex muscular architecture, supporting a muscular ground pattern of autobranch bivalve larvae that includes at least a velum muscle ring, three or four pairs of velum retractors, one or two pairs of larval retractors, two pairs of foot retractors, a pedal plexus, possibly two pairs of mantle retractors, and the muscles of the pallial line, as well as an anterior and a posterior adductor. As is typical for their molluscan kin, remodelling and loss of prominent larval features such as the velum musculature and various retractor systems appear to be also common in bivalves.The online version contains supplementary material available at 10.1007/s13127-022-00569-5." @default.
• W4284667457 created "2022-07-08" @default.
• W4284667457 creator A5010354383 @default.
• W4284667457 creator A5027635578 @default.
• W4284667457 creator A5046884720 @default.
• W4284667457 creator A5058820733 @default.
• W4284667457 creator A5038709085 @default.
• W4284667457 date "2022-07-07" @default.
• W4284667457 modified "2023-10-14" @default.
• W4284667457 title "A mosaic of conserved and novel modes of gene expression and morphogenesis in mesoderm and muscle formation of a larval bivalve" @default.
• W4284667457 cites W1518124127 @default.
• W4284667457 cites W1580002958 @default.
• W4284667457 cites W1585051866 @default.
• W4284667457 cites W1635421292 @default.
• W4284667457 cites W1658627041 @default.
• W4284667457 cites W1973082043 @default.
• W4284667457 cites W1982037385 @default.
• W4284667457 cites W1987142041 @default.
• W4284667457 cites W1991045887 @default.
• W4284667457 cites W1995410952 @default.
• W4284667457 cites W2001489844 @default.
• W4284667457 cites W2011515619 @default.
• W4284667457 cites W2017519756 @default.
• W4284667457 cites W2018071602 @default.
• W4284667457 cites W2018641010 @default.
• W4284667457 cites W2026629898 @default.
• W4284667457 cites W2026863084 @default.
• W4284667457 cites W2031872206 @default.
• W4284667457 cites W2032660869 @default.
• W4284667457 cites W2033907659 @default.
• W4284667457 cites W2034216915 @default.
• W4284667457 cites W2036962503 @default.
• W4284667457 cites W2037762195 @default.
• W4284667457 cites W2038867385 @default.
• W4284667457 cites W2043889579 @default.
• W4284667457 cites W2049159412 @default.
• W4284667457 cites W2052586526 @default.
• W4284667457 cites W2056187821 @default.
• W4284667457 cites W2060087140 @default.
• W4284667457 cites W2060426280 @default.
• W4284667457 cites W2060562600 @default.
• W4284667457 cites W2062115081 @default.
• W4284667457 cites W2063125237 @default.
• W4284667457 cites W2063528888 @default.
• W4284667457 cites W2067545701 @default.
• W4284667457 cites W2075563069 @default.
• W4284667457 cites W2080879085 @default.
• W4284667457 cites W2081565890 @default.
• W4284667457 cites W2081934233 @default.
• W4284667457 cites W2082131967 @default.
• W4284667457 cites W2086025948 @default.
• W4284667457 cites W2095137643 @default.
• W4284667457 cites W2095402185 @default.
• W4284667457 cites W2095886323 @default.
• W4284667457 cites W2103546861 @default.
• W4284667457 cites W2104444887 @default.
• W4284667457 cites W2107402789 @default.
• W4284667457 cites W2108625329 @default.
• W4284667457 cites W2109975077 @default.
• W4284667457 cites W2113362939 @default.
• W4284667457 cites W2115535683 @default.
• W4284667457 cites W2116212202 @default.
• W4284667457 cites W2117499811 @default.
• W4284667457 cites W2119279429 @default.
• W4284667457 cites W2120772351 @default.
• W4284667457 cites W2120830716 @default.
• W4284667457 cites W2122369731 @default.
• W4284667457 cites W2123350521 @default.
• W4284667457 cites W2124805860 @default.
• W4284667457 cites W2127207904 @default.
• W4284667457 cites W2127774996 @default.
• W4284667457 cites W2129622728 @default.
• W4284667457 cites W2129829180 @default.
• W4284667457 cites W2132059662 @default.
• W4284667457 cites W2132216677 @default.
• W4284667457 cites W2140030034 @default.
• W4284667457 cites W2140883383 @default.
• W4284667457 cites W2141942684 @default.
• W4284667457 cites W2143503284 @default.
• W4284667457 cites W2144654387 @default.
• W4284667457 cites W2147533449 @default.
• W4284667457 cites W2147638100 @default.
• W4284667457 cites W2151934392 @default.
• W4284667457 cites W2163451322 @default.
• W4284667457 cites W2163627198 @default.
• W4284667457 cites W2164095872 @default.
• W4284667457 cites W2165478882 @default.
• W4284667457 cites W2170964688 @default.
• W4284667457 cites W2186681592 @default.
• W4284667457 cites W2277277196 @default.
• W4284667457 cites W2289123314 @default.
• W4284667457 cites W2298583791 @default.
• W4284667457 cites W2346182764 @default.
• W4284667457 cites W2397848288 @default.
• W4284667457 cites W2461118288 @default.
• W4284667457 cites W2476515762 @default.
• W4284667457 cites W2547935826 @default.
• W4284667457 cites W2549521351 @default.

• next