FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4284668858> ?p ?o ?g. }

• W4284668858 endingPage "2656" @default.
• W4284668858 startingPage "2656" @default.
• W4284668858 abstract "A 17-year-old girl from rural Bihar presented with left-sided discoloration of periocular skin since birth [Fig. 1a and b], occasional headache, and rapidly progressive diminution of vision in the left eye (LE) for past 20 days. Uncorrected visual acuity was 6/18 in the right eye (RE) and 6/600 in LE. On examination, there was mild left-sided periocular hyperpigmentation (Tanino’s type 1A), LE temporal and inferior scleral pigmentation [Fig. 1c], Krukenberg spindle [Fig. 1d], iris heterochromia [Fig. 2a and b], anisocoria, grade 3 relative afferent pupillary defect, and raised intraocular pressure (IOP) of 38 mmHg. Gonioscopy showed open angles, Sampaolesi’s line [Fig. 2c], and increased pigmentation of trabecular meshwork [Fig. 2d]. Anterior segment optical coherence tomography showed central corneal thickness of 496 μm [Fig. 2e], open angles [Fig. 2f], and flattened iris contour in the region of hyperpigmentation [Fig. 2g]. Fundus showed marked cupping of ipsilateral optic disc with intense pigmentation [Fig. 2h]. Automated perimetry could not be performed due to poor visual acuity. The RE was normal.Figure 1: (a) Left-sided periocular hyperpigmentation (Tanino’s type 1A). (b) Temporal extent of periocular pigmentation. (c) Temporal scleral pigmentation. (d) Krukenberg spindleFigure 2: (a) Right eye showing normal iris. (b) Left eye showing iris hyperpigmentation across 12 to 8:30 o’clock (heterochromia). (c) Sampaolesi’s line as seen on left eye gonioscopy. (d) Intense trabecular pigmentation as seen on left eye gonioscopy. (e) Anterior segment optical coherence tomograph of the left eye showing central corneal thickness of 496 μm. (f) Anterior segment optical coherence tomograph of the left eye angle at 9 o’clock showing open angle and normal iris contour. (g) Anterior segment optical coherence tomograph of the left eye angle at 3 o’clock showing open angle with flattened iris contour. (h) Fundus photograph left eye showing intense pigmentation of optic disc and cup–disc ratio of 0.9:1IOP was controlled to 14 mmHg by intravenous mannitol followed by maximal topical antiglaucoma therapy. She declined consent for trabeculectomy. Discussion Nevus of Ota (oculodermal melanocytosis) is a rare benign developmental disorder of the neural crest cells characterized by melanocytic hamartomas, which can affect all ocular tissues derived from this embryonic structure.[1] It is most frequent in Asians with a prevalence of 0.014%–0.034%, with women five times more likely to be affected.[234] Raised IOP has been associated in 10.3% and optic disc pigmentation in 18.1% cases with ocular involvement.[5] Such patients may require early glaucoma filtering surgery and lifelong follow-up with ophthalmologists and dermatologists.[4] Our case highlights the importance of screening for open-angle glaucoma in children with seemingly innocuous skin pigmentation and the need to sensitize primary care physicians regarding this condition. Declaration of patient consent The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest." @default.
• W4284668858 created "2022-07-08" @default.
• W4284668858 creator A5001840718 @default.
• W4284668858 creator A5019515325 @default.
• W4284668858 creator A5020708829 @default.
• W4284668858 creator A5041590670 @default.
• W4284668858 date "2022-01-01" @default.
• W4284668858 modified "2023-10-14" @default.
• W4284668858 title "Nevus of Ota with ipsilateral optic disc pigmentation and pigmentary glaucoma" @default.
• W4284668858 cites W1541786331 @default.
• W4284668858 cites W2029263642 @default.
• W4284668858 cites W2054405767 @default.
• W4284668858 cites W2499209652 @default.
• W4284668858 doi "https://doi.org/10.4103/ijo.ijo_2893_21" @default.
• W4284668858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35791191" @default.
• W4284668858 hasPublicationYear "2022" @default.
• W4284668858 type Work @default.
• W4284668858 citedByCount "1" @default.
• W4284668858 countsByYear W42846688582022 @default.
• W4284668858 crossrefType "journal-article" @default.
• W4284668858 hasAuthorship W4284668858A5001840718 @default.
• W4284668858 hasAuthorship W4284668858A5019515325 @default.
• W4284668858 hasAuthorship W4284668858A5020708829 @default.
• W4284668858 hasAuthorship W4284668858A5041590670 @default.
• W4284668858 hasBestOaLocation W42846688581 @default.
• W4284668858 hasConcept C104317684 @default.
• W4284668858 hasConcept C105702510 @default.
• W4284668858 hasConcept C118487528 @default.
• W4284668858 hasConcept C16005928 @default.
• W4284668858 hasConcept C184297639 @default.
• W4284668858 hasConcept C2776391266 @default.
• W4284668858 hasConcept C2776608714 @default.
• W4284668858 hasConcept C2776728111 @default.
• W4284668858 hasConcept C2777100477 @default.
• W4284668858 hasConcept C2778527774 @default.
• W4284668858 hasConcept C2779503344 @default.
• W4284668858 hasConcept C2779735895 @default.
• W4284668858 hasConcept C2780892088 @default.
• W4284668858 hasConcept C2781092963 @default.
• W4284668858 hasConcept C2781121420 @default.
• W4284668858 hasConcept C38652104 @default.
• W4284668858 hasConcept C41008148 @default.
• W4284668858 hasConcept C55493867 @default.
• W4284668858 hasConcept C71924100 @default.
• W4284668858 hasConcept C86803240 @default.
• W4284668858 hasConceptScore W4284668858C104317684 @default.
• W4284668858 hasConceptScore W4284668858C105702510 @default.
• W4284668858 hasConceptScore W4284668858C118487528 @default.
• W4284668858 hasConceptScore W4284668858C16005928 @default.
• W4284668858 hasConceptScore W4284668858C184297639 @default.
• W4284668858 hasConceptScore W4284668858C2776391266 @default.
• W4284668858 hasConceptScore W4284668858C2776608714 @default.
• W4284668858 hasConceptScore W4284668858C2776728111 @default.
• W4284668858 hasConceptScore W4284668858C2777100477 @default.
• W4284668858 hasConceptScore W4284668858C2778527774 @default.
• W4284668858 hasConceptScore W4284668858C2779503344 @default.
• W4284668858 hasConceptScore W4284668858C2779735895 @default.
• W4284668858 hasConceptScore W4284668858C2780892088 @default.
• W4284668858 hasConceptScore W4284668858C2781092963 @default.
• W4284668858 hasConceptScore W4284668858C2781121420 @default.
• W4284668858 hasConceptScore W4284668858C38652104 @default.
• W4284668858 hasConceptScore W4284668858C41008148 @default.
• W4284668858 hasConceptScore W4284668858C55493867 @default.
• W4284668858 hasConceptScore W4284668858C71924100 @default.
• W4284668858 hasConceptScore W4284668858C86803240 @default.
• W4284668858 hasIssue "7" @default.
• W4284668858 hasLocation W42846688581 @default.
• W4284668858 hasLocation W42846688582 @default.
• W4284668858 hasLocation W42846688583 @default.
• W4284668858 hasLocation W42846688584 @default.
• W4284668858 hasOpenAccess W4284668858 @default.
• W4284668858 hasPrimaryLocation W42846688581 @default.
• W4284668858 hasRelatedWork W172323342 @default.
• W4284668858 hasRelatedWork W2057916387 @default.
• W4284668858 hasRelatedWork W2062512802 @default.
• W4284668858 hasRelatedWork W2310463995 @default.
• W4284668858 hasRelatedWork W2407142082 @default.
• W4284668858 hasRelatedWork W2519892206 @default.
• W4284668858 hasRelatedWork W2966491370 @default.
• W4284668858 hasRelatedWork W3209287814 @default.
• W4284668858 hasRelatedWork W4284668858 @default.
• W4284668858 hasRelatedWork W4311450865 @default.
• W4284668858 hasVolume "70" @default.
• W4284668858 isParatext "false" @default.
• W4284668858 isRetracted "false" @default.
• W4284668858 workType "article" @default.