Matches in SemOpenAlex for { <https://semopenalex.org/work/W4284692613> ?p ?o ?g. }
- W4284692613 endingPage "1796" @default.
- W4284692613 startingPage "1796" @default.
- W4284692613 abstract "This study evaluated the effect of the extract and fractions of Bauhinia holophylla on Candida albicans planktonic growth, biofilm formation, mature biofilm, and hyphae growth. Three C. albicans strains (SC5314, ATCC 18804, and ATCC 10231) were tested. The crude extract and the fractions were obtained by exhaustive percolation and liquid-liquid partition, respectively. Phytochemical analyses of B. holophylla extract and fractions were performed using high-performance liquid chromatography coupled with a diode-array detector and mass spectrometry (HPLC-DAD-MS). A microdilution assay was used to evaluate the effect of the B. holophylla extract and fractions on C. albicans planktonic growth, and crystal violet staining was used to measure the total biomass of the biofilm. Hyphae growth was analyzed using light microscopy. Thirteen flavonoids were identified, with a predominance of the flavonol-3-O-glycoside type based on quercetin, myricetin, and kaempferol. Flavonoid-rich fractions of B. holophylla leaves displayed antifungal activity and inhibited both biofilm formation and hyphae growth in all the tested strains, but were not effective on C. albicans planktonic growth and mature biofilm. This study indicates that flavonoid-rich fractions from B. holophylla leaves interfere with the virulence of Candida species and support the use of Bauhinia spp. in folk medicine to treat infections." @default.
- W4284692613 created "2022-07-08" @default.
- W4284692613 creator A5001820908 @default.
- W4284692613 creator A5022516804 @default.
- W4284692613 creator A5032369351 @default.
- W4284692613 creator A5037193500 @default.
- W4284692613 creator A5054168447 @default.
- W4284692613 creator A5061080668 @default.
- W4284692613 date "2022-07-07" @default.
- W4284692613 modified "2023-10-14" @default.
- W4284692613 title "Flavonoid-Rich Fractions of Bauhinia holophylla Leaves Inhibit Candida albicans Biofilm Formation and Hyphae Growth" @default.
- W4284692613 cites W1523227998 @default.
- W4284692613 cites W1583489850 @default.
- W4284692613 cites W1775855178 @default.
- W4284692613 cites W1965169166 @default.
- W4284692613 cites W2002379595 @default.
- W4284692613 cites W2045206337 @default.
- W4284692613 cites W2045825103 @default.
- W4284692613 cites W2046814973 @default.
- W4284692613 cites W2078424158 @default.
- W4284692613 cites W2140388345 @default.
- W4284692613 cites W2143561163 @default.
- W4284692613 cites W2144035662 @default.
- W4284692613 cites W2149048864 @default.
- W4284692613 cites W2162335077 @default.
- W4284692613 cites W2170764510 @default.
- W4284692613 cites W2175584163 @default.
- W4284692613 cites W2219990459 @default.
- W4284692613 cites W2252911663 @default.
- W4284692613 cites W2276769404 @default.
- W4284692613 cites W2291984511 @default.
- W4284692613 cites W2559348332 @default.
- W4284692613 cites W2590995400 @default.
- W4284692613 cites W2745691487 @default.
- W4284692613 cites W2771255774 @default.
- W4284692613 cites W2790728643 @default.
- W4284692613 cites W2792847166 @default.
- W4284692613 cites W2799773319 @default.
- W4284692613 cites W2810333003 @default.
- W4284692613 cites W2885698573 @default.
- W4284692613 cites W2886901827 @default.
- W4284692613 cites W2895839658 @default.
- W4284692613 cites W2900436168 @default.
- W4284692613 cites W2907528228 @default.
- W4284692613 cites W2932341513 @default.
- W4284692613 cites W2942039246 @default.
- W4284692613 cites W2946908776 @default.
- W4284692613 cites W2954362930 @default.
- W4284692613 cites W2963970485 @default.
- W4284692613 cites W2968373229 @default.
- W4284692613 cites W2976138411 @default.
- W4284692613 cites W2981428424 @default.
- W4284692613 cites W3024600634 @default.
- W4284692613 cites W3024633412 @default.
- W4284692613 cites W3024750580 @default.
- W4284692613 cites W3044631602 @default.
- W4284692613 cites W3074516067 @default.
- W4284692613 cites W3082436295 @default.
- W4284692613 cites W3095449662 @default.
- W4284692613 cites W3096406530 @default.
- W4284692613 cites W3096849859 @default.
- W4284692613 cites W3111870857 @default.
- W4284692613 cites W3114403719 @default.
- W4284692613 cites W3176251948 @default.
- W4284692613 cites W3177468222 @default.
- W4284692613 cites W3200574457 @default.
- W4284692613 doi "https://doi.org/10.3390/plants11141796" @default.
- W4284692613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35890430" @default.
- W4284692613 hasPublicationYear "2022" @default.
- W4284692613 type Work @default.
- W4284692613 citedByCount "1" @default.
- W4284692613 countsByYear W42846926132023 @default.
- W4284692613 crossrefType "journal-article" @default.
- W4284692613 hasAuthorship W4284692613A5001820908 @default.
- W4284692613 hasAuthorship W4284692613A5022516804 @default.
- W4284692613 hasAuthorship W4284692613A5032369351 @default.
- W4284692613 hasAuthorship W4284692613A5037193500 @default.
- W4284692613 hasAuthorship W4284692613A5054168447 @default.
- W4284692613 hasAuthorship W4284692613A5061080668 @default.
- W4284692613 hasBestOaLocation W42846926131 @default.
- W4284692613 hasConcept C145081991 @default.
- W4284692613 hasConcept C185592680 @default.
- W4284692613 hasConcept C2777810353 @default.
- W4284692613 hasConcept C2778004101 @default.
- W4284692613 hasConcept C2778173338 @default.
- W4284692613 hasConcept C2779054382 @default.
- W4284692613 hasConcept C2780917455 @default.
- W4284692613 hasConcept C2781263971 @default.
- W4284692613 hasConcept C523546767 @default.
- W4284692613 hasConcept C54355233 @default.
- W4284692613 hasConcept C55493867 @default.
- W4284692613 hasConcept C58123911 @default.
- W4284692613 hasConcept C59822182 @default.
- W4284692613 hasConcept C86803240 @default.
- W4284692613 hasConcept C89423630 @default.
- W4284692613 hasConcept C90080823 @default.
- W4284692613 hasConceptScore W4284692613C145081991 @default.
- W4284692613 hasConceptScore W4284692613C185592680 @default.