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- W4284692968 endingPage "3943" @default.
- W4284692968 startingPage "3943" @default.
- W4284692968 abstract "Atopic dermatitis (AD) is an inflammatory skin disease of multiple phenotypes and endotypes, and is highly prevalent in children. Many people of all ages, including active adolescents, pregnant women, and the elderly, suffer from AD, experiencing chronicity, flares, and unexpected relapse. Dexpanthenol has multiple pharmacological effects and has been employed to treat various skin disorders such as AD. We aimed to summarize the up-to-date evidence relating to dexpanthenol and to provide a consensus on how to use dexpanthenol effectively for the treatment of AD.The evidence to date on the application and efficacy of dexpanthenol in AD was reviewed. The literature search focused on dexpanthenol use and the improvement of skin barrier function, the prevention of acute flares, and its topical corticosteroid (TCS) sparing effects. Evidence and recommendations for special groups such as pregnant women, and the effects of dexpanthenol and emollient plus in maintenance therapy, were also summarized.Dexpanthenol is effective and well-tolerated for the treatment of AD. Dexpanthenol improves skin barrier function, reduces acute and frequent flares, has a significant TCS sparing effect, and enhances wound healing for skin lesions.This review article provides helpful advice for clinicians and patients on the proper maintenance treatment of AD. Dexpanthenol, as an active ingredient in ointments or emollients, is suitable for the treatment and maintenance of AD. This paper will guide dermatologists and clinicians to consider dexpanthenol as a treatment option for mild to moderate AD." @default.
- W4284692968 created "2022-07-08" @default.
- W4284692968 creator A5023043930 @default.
- W4284692968 creator A5030914867 @default.
- W4284692968 creator A5041155675 @default.
- W4284692968 creator A5042806530 @default.
- W4284692968 date "2022-07-06" @default.
- W4284692968 modified "2023-09-30" @default.
- W4284692968 title "Use of Dexpanthenol for Atopic Dermatitis—Benefits and Recommendations Based on Current Evidence" @default.
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