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• W4284693997 abstract "A growing body of literature has emphasized the importance of biobehavioral processes – defined as the interaction of behavior, psychology, socioenvironmental factors, and biological processes – for clinical outcomes among transplantation and cellular therapy (TCT) patients. TCT recipients are especially vulnerable to distress associated with pandemic conditions and represent a notably immunocompromised group at greater risk for SARS-CoV-2 infection with substantially worse outcomes. The summation of both the immunologic and psychologic vulnerability of TCT patients renders them particularly susceptible to adverse biobehavioral sequelae associated with the Covid-19 pandemic. Stress and adverse psychosocial factors alter neural and endocrine pathways through sympathetic nervous system and hypothalamic-pituitary-adrenal axis signaling that ultimately affect gene regulation in immune cells. Reciprocally, global inflammation and immune dysregulation related to TCT contribute to dysregulation of neuroendocrine and central nervous system function, resulting in the symptom profile of depression, fatigue, sleep disturbance, and cognitive dysfunction. In this article, we draw upon literature on immunology, psychology, neuroscience, hematology and oncology, Covid-19 pathophysiology, and TCT processes to discuss how they may intersect to influence TCT outcomes, with the goal of providing an overview of the significance of biobehavioral factors in understanding the relationship between Covid-19 and TCT, now and for the future. We discuss the roles of depression, anxiety, fatigue, sleep, social isolation and loneliness, and neurocognitive impairment, as well as specific implications for sub-populations of interest, including pediatrics, caregivers, and TCT donors. Finally, we address protective psychological processes that may optimize biobehavioral outcomes affected by Covid-19." @default.
• W4284693997 created "2022-07-08" @default.
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• W4284693997 date "2022-07-05" @default.
• W4284693997 modified "2023-09-30" @default.
• W4284693997 title "Biobehavioral Implications of Covid-19 for Transplantation and Cellular Therapy Recipients" @default.
• W4284693997 cites W144370295 @default.
• W4284693997 cites W1801578582 @default.
• W4284693997 cites W1884441019 @default.
• W4284693997 cites W1959055352 @default.
• W4284693997 cites W1966738818 @default.
• W4284693997 cites W1971494202 @default.
• W4284693997 cites W1975020079 @default.
• W4284693997 cites W1979817742 @default.
• W4284693997 cites W1981654563 @default.
• W4284693997 cites W1991464448 @default.
• W4284693997 cites W1996681638 @default.
• W4284693997 cites W2000445391 @default.
• W4284693997 cites W2002577582 @default.
• W4284693997 cites W2003885562 @default.
• W4284693997 cites W2010023289 @default.
• W4284693997 cites W2014365381 @default.
• W4284693997 cites W2014597408 @default.
• W4284693997 cites W2021094789 @default.
• W4284693997 cites W2023644363 @default.
• W4284693997 cites W2025723091 @default.
• W4284693997 cites W2025845020 @default.
• W4284693997 cites W2028775192 @default.
• W4284693997 cites W2029103908 @default.
• W4284693997 cites W2032339217 @default.
• W4284693997 cites W2034922009 @default.
• W4284693997 cites W2035707157 @default.
• W4284693997 cites W2040350917 @default.
• W4284693997 cites W2046582153 @default.
• W4284693997 cites W2048808569 @default.
• W4284693997 cites W2064804693 @default.
• W4284693997 cites W2065493546 @default.
• W4284693997 cites W2066823109 @default.
• W4284693997 cites W2075427208 @default.
• W4284693997 cites W2078619626 @default.
• W4284693997 cites W2080393483 @default.
• W4284693997 cites W2080570400 @default.
• W4284693997 cites W2086243699 @default.
• W4284693997 cites W2088883890 @default.
• W4284693997 cites W2089385262 @default.
• W4284693997 cites W2094249939 @default.
• W4284693997 cites W2096710347 @default.
• W4284693997 cites W2098443706 @default.
• W4284693997 cites W2098472703 @default.
• W4284693997 cites W2100687673 @default.
• W4284693997 cites W2103638552 @default.
• W4284693997 cites W2104469462 @default.
• W4284693997 cites W2106971338 @default.
• W4284693997 cites W2118796952 @default.
• W4284693997 cites W2123397298 @default.
• W4284693997 cites W2125158184 @default.
• W4284693997 cites W2131130461 @default.
• W4284693997 cites W2131409492 @default.
• W4284693997 cites W2133868657 @default.
• W4284693997 cites W2134276904 @default.
• W4284693997 cites W2138998316 @default.
• W4284693997 cites W2139317496 @default.
• W4284693997 cites W2141140442 @default.
• W4284693997 cites W2141382054 @default.
• W4284693997 cites W2145626070 @default.
• W4284693997 cites W2145636091 @default.
• W4284693997 cites W2148230248 @default.
• W4284693997 cites W2150051772 @default.
• W4284693997 cites W2156982169 @default.
• W4284693997 cites W2160666689 @default.
• W4284693997 cites W2164859678 @default.
• W4284693997 cites W2165243546 @default.
• W4284693997 cites W2168825005 @default.
• W4284693997 cites W2172657862 @default.
• W4284693997 cites W2174948234 @default.
• W4284693997 cites W2193100439 @default.
• W4284693997 cites W2201607793 @default.
• W4284693997 cites W2222364322 @default.
• W4284693997 cites W2257342655 @default.
• W4284693997 cites W2293937671 @default.
• W4284693997 cites W2336763478 @default.
• W4284693997 cites W2340435799 @default.
• W4284693997 cites W2396490410 @default.
• W4284693997 cites W2427971560 @default.
• W4284693997 cites W2462401297 @default.
• W4284693997 cites W2463112166 @default.
• W4284693997 cites W2521208781 @default.
• W4284693997 cites W2553484792 @default.
• W4284693997 cites W2559360016 @default.

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