FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4284697211> ?p ?o ?g. }

• W4284697211 endingPage "95" @default.
• W4284697211 startingPage "95" @default.
• W4284697211 abstract "In this work, we report the synthesis and characterization of a mono-nuclear “two wall” aryl-extended calix[4]pyrrole receptor (2Au) decorated with an acetylide-gold(I)-PTA complex at its upper rim. We describe the 1H NMR titration experiments of 2Au and its “two wall” aryl-extended calix[4]pyrrole synthetic precursors: the non-symmetric mono-iodo-mono-ethynyl 2 and the symmetric bis-iodo 3 with TBACl in dichloromethane and acetone solution. In acetone solution, we use isothermal titration calorimetry (ITC) experiments to thermodynamically characterize the formed 1:1 chloride complexes and perform pair-wise competitive binding experiments. In both solvents, we measured a decrease in the binding constant of the mono-nuclear 2Au complex for chloride compared to the parent mono-iodo-mono-ethynyl 2. In turn, receptor 2 also shows a reduction in binding affinity for chloride compared to its precursor bis-iodo calix[4]pyrrole 3. The free energy differences (∆G) of the 1:1 chloride complexes cannot be exclusively attributed to their dissimilar electrostatic surface potential values either at the center of the meso-phenyl wall or its para-substituent. We conclude that solvation/desolvation processes play an important role in the stabilization of the chloride complexes. In acetone solution and in the presence of TBACl, 6Au, a reference compound for the acetylide Au(I)•PTA unit, produces a bis(alkynyl)gold(I) anionic complex [7Au]−. Thus, the observation of two separate sets of signals for the bound aromatic calix[4]pyrrole protons, when more than 1 equiv. of the salt is added, is assigned to the formation of the chloride complexes of 2Au and of the “in situ” formed calix[4]pyrrole anionic dimer [8Au]−. Finally, preliminary data obtained in cell viability assays of 2Au and 6Au with human cancer cells lines assign them with moderate activities showing that the calix[4]pyrrole unit is not relevant." @default.
• W4284697211 created "2022-07-08" @default.
• W4284697211 creator A5032340885 @default.
• W4284697211 creator A5084842559 @default.
• W4284697211 creator A5087806852 @default.
• W4284697211 creator A5091406291 @default.
• W4284697211 date "2022-07-05" @default.
• W4284697211 modified "2023-10-14" @default.
• W4284697211 title "Chloride Binding Properties of a Macrocyclic Receptor Equipped with an Acetylide Gold(I) Complex: Synthesis, Characterization, Reactivity, and Cytotoxicity Studies" @default.
• W4284697211 cites W1977248029 @default.
• W4284697211 cites W1977994398 @default.
• W4284697211 cites W1978499643 @default.
• W4284697211 cites W1988091937 @default.
• W4284697211 cites W1988924496 @default.
• W4284697211 cites W1996273492 @default.
• W4284697211 cites W1999598739 @default.
• W4284697211 cites W2003609201 @default.
• W4284697211 cites W2006656408 @default.
• W4284697211 cites W2008527242 @default.
• W4284697211 cites W2013824746 @default.
• W4284697211 cites W2016800344 @default.
• W4284697211 cites W2028022118 @default.
• W4284697211 cites W2030687437 @default.
• W4284697211 cites W2045136684 @default.
• W4284697211 cites W2059733965 @default.
• W4284697211 cites W2085341294 @default.
• W4284697211 cites W2092157292 @default.
• W4284697211 cites W2095002979 @default.
• W4284697211 cites W2096747776 @default.
• W4284697211 cites W2102299071 @default.
• W4284697211 cites W2114580148 @default.
• W4284697211 cites W2118826907 @default.
• W4284697211 cites W2141887930 @default.
• W4284697211 cites W2147157740 @default.
• W4284697211 cites W2178393423 @default.
• W4284697211 cites W2300080499 @default.
• W4284697211 cites W2322976047 @default.
• W4284697211 cites W2324006907 @default.
• W4284697211 cites W2333809830 @default.
• W4284697211 cites W2333872381 @default.
• W4284697211 cites W2761909854 @default.
• W4284697211 cites W2797129015 @default.
• W4284697211 cites W2965941316 @default.
• W4284697211 cites W2991165988 @default.
• W4284697211 cites W2999458034 @default.
• W4284697211 cites W3048722082 @default.
• W4284697211 cites W3126624531 @default.
• W4284697211 cites W4200501256 @default.
• W4284697211 doi "https://doi.org/10.3390/inorganics10070095" @default.
• W4284697211 hasPublicationYear "2022" @default.
• W4284697211 type Work @default.
• W4284697211 citedByCount "2" @default.
• W4284697211 countsByYear W42846972112022 @default.
• W4284697211 countsByYear W42846972112023 @default.
• W4284697211 crossrefType "journal-article" @default.
• W4284697211 hasAuthorship W4284697211A5032340885 @default.
• W4284697211 hasAuthorship W4284697211A5084842559 @default.
• W4284697211 hasAuthorship W4284697211A5087806852 @default.
• W4284697211 hasAuthorship W4284697211A5091406291 @default.
• W4284697211 hasBestOaLocation W42846972111 @default.
• W4284697211 hasConcept C107824862 @default.
• W4284697211 hasConcept C142724271 @default.
• W4284697211 hasConcept C147789679 @default.
• W4284697211 hasConcept C155647269 @default.
• W4284697211 hasConcept C156911925 @default.
• W4284697211 hasConcept C178790620 @default.
• W4284697211 hasConcept C179104552 @default.
• W4284697211 hasConcept C184866935 @default.
• W4284697211 hasConcept C185592680 @default.
• W4284697211 hasConcept C188027245 @default.
• W4284697211 hasConcept C204787440 @default.
• W4284697211 hasConcept C2776910235 @default.
• W4284697211 hasConcept C2778689049 @default.
• W4284697211 hasConcept C2778695967 @default.
• W4284697211 hasConcept C2779400197 @default.
• W4284697211 hasConcept C2779627003 @default.
• W4284697211 hasConcept C32786932 @default.
• W4284697211 hasConcept C55493867 @default.
• W4284697211 hasConcept C71924100 @default.
• W4284697211 hasConceptScore W4284697211C107824862 @default.
• W4284697211 hasConceptScore W4284697211C142724271 @default.
• W4284697211 hasConceptScore W4284697211C147789679 @default.
• W4284697211 hasConceptScore W4284697211C155647269 @default.
• W4284697211 hasConceptScore W4284697211C156911925 @default.
• W4284697211 hasConceptScore W4284697211C178790620 @default.
• W4284697211 hasConceptScore W4284697211C179104552 @default.
• W4284697211 hasConceptScore W4284697211C184866935 @default.
• W4284697211 hasConceptScore W4284697211C185592680 @default.
• W4284697211 hasConceptScore W4284697211C188027245 @default.
• W4284697211 hasConceptScore W4284697211C204787440 @default.
• W4284697211 hasConceptScore W4284697211C2776910235 @default.
• W4284697211 hasConceptScore W4284697211C2778689049 @default.
• W4284697211 hasConceptScore W4284697211C2778695967 @default.
• W4284697211 hasConceptScore W4284697211C2779400197 @default.
• W4284697211 hasConceptScore W4284697211C2779627003 @default.
• W4284697211 hasConceptScore W4284697211C32786932 @default.
• W4284697211 hasConceptScore W4284697211C55493867 @default.
• W4284697211 hasConceptScore W4284697211C71924100 @default.

• next