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- W4284698220 endingPage "1639" @default.
- W4284698220 startingPage "1639" @default.
- W4284698220 abstract "Myelodysplastic syndromes (MDSs) are clonal disorders characterized by ineffective hematopoiesis, resulting in cytopenias and a risk of developing acute myeloid leukemia. In addition to mutations affecting hematopoietic stem cells (HSCs), numerous studies have highlighted the role of the bone marrow microenvironment (BMME) in the development of MDSs. The mesenchymal niche represents a key component of the BMME. In this review, we discuss the role of the mesenchymal niche in the pathophysiology of MDS and provide an overview of currently available in vitro and in vivo models that can be used to study the effects of the mesenchymal niche on HSCs." @default.
- W4284698220 created "2022-07-08" @default.
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- W4284698220 date "2022-07-05" @default.
- W4284698220 modified "2023-09-30" @default.
- W4284698220 title "The Mesenchymal Niche in Myelodysplastic Syndromes" @default.
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- W4284698220 doi "https://doi.org/10.3390/diagnostics12071639" @default.
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