Matches in SemOpenAlex for { <https://semopenalex.org/work/W4284959766> ?p ?o ?g. }
- W4284959766 endingPage "e29456" @default.
- W4284959766 startingPage "e29456" @default.
- W4284959766 abstract "Sacubitril/valsartan, the first angiotensin receptor neprilysin inhibitor approved by the Food and Drug Administration for marketing, has been shown to reduce the risk of cardiovascular death or heart failure hospitalization and improve symptoms in patients with chronic heart failure with a reduced ejection fraction. However, some researchers have also found that sacubitril/valsartan has an antiarrhythmic effect. The mechanism by which sacubitril/valsartan reduces the mortality associated with malignant ventricular arrhythmias is not precise. Many studies have concluded that ventricular arrhythmia is associated with a reduction in myocardial fibrosis. This article reviews the current understanding of the effects of sacubitril/valsartan on the reduction of ventricular arrhythmia and explains its possible mechanisms. The results of this study suggest that sacubitril/valsartan reduces the occurrence of appropriate implantable cardioverter-defibrillator shocks. Meanwhile, sacubitril/valsartan may reduce the occurrence of ventricular arrhythmias by affecting 3 pathways of B-type natriuretic peptide, Angiotensin II, and Bradykinin. The conclusion of this study is that sacubitril/valsartan reduces the number of implantable cardioverter-defibrillator shocks and ventricular arrhythmias in heart failure with reduced ejection fraction patients." @default.
- W4284959766 created "2022-07-10" @default.
- W4284959766 creator A5021028404 @default.
- W4284959766 creator A5024098878 @default.
- W4284959766 creator A5032469771 @default.
- W4284959766 creator A5052441498 @default.
- W4284959766 creator A5080683222 @default.
- W4284959766 creator A5083778564 @default.
- W4284959766 creator A5088526794 @default.
- W4284959766 creator A5090435545 @default.
- W4284959766 date "2022-07-08" @default.
- W4284959766 modified "2023-10-01" @default.
- W4284959766 title "A narrative review on sacubitril/valsartan and ventricular arrhythmias" @default.
- W4284959766 cites W1540580215 @default.
- W4284959766 cites W1836315310 @default.
- W4284959766 cites W1911769041 @default.
- W4284959766 cites W1970709580 @default.
- W4284959766 cites W1973740388 @default.
- W4284959766 cites W1975952670 @default.
- W4284959766 cites W1983734540 @default.
- W4284959766 cites W1996936769 @default.
- W4284959766 cites W2032130572 @default.
- W4284959766 cites W2042824671 @default.
- W4284959766 cites W2043571529 @default.
- W4284959766 cites W2063827230 @default.
- W4284959766 cites W2064821822 @default.
- W4284959766 cites W2066778848 @default.
- W4284959766 cites W2095835518 @default.
- W4284959766 cites W2098418963 @default.
- W4284959766 cites W2113698123 @default.
- W4284959766 cites W2116655536 @default.
- W4284959766 cites W2132106701 @default.
- W4284959766 cites W2135589818 @default.
- W4284959766 cites W2151670827 @default.
- W4284959766 cites W2164375876 @default.
- W4284959766 cites W2202895441 @default.
- W4284959766 cites W2274091016 @default.
- W4284959766 cites W2292846538 @default.
- W4284959766 cites W2299395117 @default.
- W4284959766 cites W2301176136 @default.
- W4284959766 cites W2475677373 @default.
- W4284959766 cites W2562411701 @default.
- W4284959766 cites W2605325887 @default.
- W4284959766 cites W2605980487 @default.
- W4284959766 cites W2753475313 @default.
- W4284959766 cites W2754704407 @default.
- W4284959766 cites W2770689224 @default.
- W4284959766 cites W2783769692 @default.
- W4284959766 cites W2794277378 @default.
- W4284959766 cites W2803690874 @default.
- W4284959766 cites W2803987989 @default.
- W4284959766 cites W2890618895 @default.
- W4284959766 cites W2891211611 @default.
- W4284959766 cites W2915125346 @default.
- W4284959766 cites W2920919776 @default.
- W4284959766 cites W2921706473 @default.
- W4284959766 cites W2949251591 @default.
- W4284959766 cites W2951128185 @default.
- W4284959766 cites W2953887972 @default.
- W4284959766 cites W2972057462 @default.
- W4284959766 cites W2975408293 @default.
- W4284959766 cites W2979060055 @default.
- W4284959766 cites W2999216526 @default.
- W4284959766 cites W3012424142 @default.
- W4284959766 cites W3012640067 @default.
- W4284959766 cites W3015366624 @default.
- W4284959766 cites W3017041658 @default.
- W4284959766 cites W3044202886 @default.
- W4284959766 cites W3107658679 @default.
- W4284959766 cites W3117073666 @default.
- W4284959766 cites W3122972572 @default.
- W4284959766 cites W3128795655 @default.
- W4284959766 cites W3137633231 @default.
- W4284959766 cites W3138698930 @default.
- W4284959766 cites W3176615134 @default.
- W4284959766 cites W3194261284 @default.
- W4284959766 cites W3197386396 @default.
- W4284959766 cites W3204266856 @default.
- W4284959766 doi "https://doi.org/10.1097/md.0000000000029456" @default.
- W4284959766 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35801732" @default.
- W4284959766 hasPublicationYear "2022" @default.
- W4284959766 type Work @default.
- W4284959766 citedByCount "1" @default.
- W4284959766 countsByYear W42849597662023 @default.
- W4284959766 crossrefType "journal-article" @default.
- W4284959766 hasAuthorship W4284959766A5021028404 @default.
- W4284959766 hasAuthorship W4284959766A5024098878 @default.
- W4284959766 hasAuthorship W4284959766A5032469771 @default.
- W4284959766 hasAuthorship W4284959766A5052441498 @default.
- W4284959766 hasAuthorship W4284959766A5080683222 @default.
- W4284959766 hasAuthorship W4284959766A5083778564 @default.
- W4284959766 hasAuthorship W4284959766A5088526794 @default.
- W4284959766 hasAuthorship W4284959766A5090435545 @default.
- W4284959766 hasBestOaLocation W42849597661 @default.
- W4284959766 hasConcept C104826730 @default.
- W4284959766 hasConcept C104849204 @default.
- W4284959766 hasConcept C126322002 @default.
- W4284959766 hasConcept C164705383 @default.