FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4284960606> ?p ?o ?g. }

• W4284960606 abstract "Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic disease affecting the spine and sacroiliac joints. To investigate whether there are differences in inflammatory and chronic structural damages, as assessed by a semiquantitative MRI scoring method, between non-radiographic axial spondyloarthritis (nr-axSpA) and ankylosing spondylitis (AS) patients with active inflammation at baseline, and to evaluate the treatment response in these patients after 3 months of tumor necrosis factor-alpha (TNF-α) inhibitor treatment.Fifty-eight axSpA patients with active inflammation were included in the study. The patients were divided into nr-axSpA group and AS group. MRI examinations of the sacroiliac joints were performed before and after treatment. Inflammatory and structural damages in these patients were assessed using the established Spondyloarthritis Research Consortium of Canada (SPARCC) inflammation and sacroiliac joint structural (SSS) scoring methods, which are two MRI-based scoring methods. The SPARCC score, SSS score, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) level were compared between the two groups.At baseline, SPARCC scores for patients in the nr-axSpA and AS groups did not differ significantly (P > 0.05); however, SSS scores for fat metaplasia, erosion, and backfill for patients in the AS group were significantly higher (P < 0.001). Compared with baseline, SPARCC scores were significantly decreased in both groups after treatment (P < 0.001); however, after treatment, no statistically significant difference was found regarding SPARCC scores between the AS and nr-axSpA groups. Compared with baseline, a significant increase in the SSS scores for fat metaplasia and backfill (P < 0.001) and a significant decrease in the SSS scores for erosion (P < 0.001) were observed in all axSpA patients. Changes in the SPARCC score was inversely correlated with the changes in the SSS score for fat metaplasia (r = - 0.634, P < 0.001). Changes in the SSS score for backfill were positively correlated with the changes in the SSS score for fat metaplasia (r = 0.277, P < 0.05) and inversely correlated with those for erosion (r = - 0.443, P < 0.001).The SPARCC and SSS scoring systems can be used to assess inflammatory and chronic structural damages as well as treatment responses in patients with axSpA. More severe structural damages were seen in AS patients. TNF-α inhibitor treatment for 3 months could effectively reduce inflammation in axSpA patients." @default.
• W4284960606 created "2022-07-10" @default.
• W4284960606 creator A5004589609 @default.
• W4284960606 creator A5008326242 @default.
• W4284960606 creator A5055264142 @default.
• W4284960606 creator A5071020673 @default.
• W4284960606 creator A5074980795 @default.
• W4284960606 date "2022-07-08" @default.
• W4284960606 modified "2023-10-14" @default.
• W4284960606 title "Evaluation of active inflammation, chronic structural damage, and response to treatment of sacroiliitis in axial spondyloarthritis using the Spondyloarthritis research consortium of Canada scoring system" @default.
• W4284960606 cites W1688971704 @default.
• W4284960606 cites W1816040004 @default.
• W4284960606 cites W1826046665 @default.
• W4284960606 cites W1966756689 @default.
• W4284960606 cites W1969370025 @default.
• W4284960606 cites W1974635592 @default.
• W4284960606 cites W2015406536 @default.
• W4284960606 cites W2026876444 @default.
• W4284960606 cites W2048805333 @default.
• W4284960606 cites W2052996963 @default.
• W4284960606 cites W2079392881 @default.
• W4284960606 cites W2104749385 @default.
• W4284960606 cites W2105285849 @default.
• W4284960606 cites W2118596556 @default.
• W4284960606 cites W2135336890 @default.
• W4284960606 cites W2258826212 @default.
• W4284960606 cites W2294620624 @default.
• W4284960606 cites W2317920591 @default.
• W4284960606 cites W2474510828 @default.
• W4284960606 cites W2523666037 @default.
• W4284960606 cites W2599618767 @default.
• W4284960606 cites W2622188745 @default.
• W4284960606 cites W2758911649 @default.
• W4284960606 cites W2768148120 @default.
• W4284960606 cites W2892277315 @default.
• W4284960606 cites W2900105466 @default.
• W4284960606 cites W2946715899 @default.
• W4284960606 cites W2968744974 @default.
• W4284960606 cites W3130842105 @default.
• W4284960606 cites W4211033155 @default.
• W4284960606 doi "https://doi.org/10.1186/s12891-022-05609-x" @default.
• W4284960606 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35804360" @default.
• W4284960606 hasPublicationYear "2022" @default.
• W4284960606 type Work @default.
• W4284960606 citedByCount "2" @default.
• W4284960606 countsByYear W42849606062023 @default.
• W4284960606 crossrefType "journal-article" @default.
• W4284960606 hasAuthorship W4284960606A5004589609 @default.
• W4284960606 hasAuthorship W4284960606A5008326242 @default.
• W4284960606 hasAuthorship W4284960606A5055264142 @default.
• W4284960606 hasAuthorship W4284960606A5071020673 @default.
• W4284960606 hasAuthorship W4284960606A5074980795 @default.
• W4284960606 hasBestOaLocation W42849606061 @default.
• W4284960606 hasConcept C126322002 @default.
• W4284960606 hasConcept C1862650 @default.
• W4284960606 hasConcept C198451711 @default.
• W4284960606 hasConcept C2776213234 @default.
• W4284960606 hasConcept C2776914184 @default.
• W4284960606 hasConcept C2777402515 @default.
• W4284960606 hasConcept C2778143017 @default.
• W4284960606 hasConcept C2778579456 @default.
• W4284960606 hasConcept C71924100 @default.
• W4284960606 hasConcept C90924648 @default.
• W4284960606 hasConceptScore W4284960606C126322002 @default.
• W4284960606 hasConceptScore W4284960606C1862650 @default.
• W4284960606 hasConceptScore W4284960606C198451711 @default.
• W4284960606 hasConceptScore W4284960606C2776213234 @default.
• W4284960606 hasConceptScore W4284960606C2776914184 @default.
• W4284960606 hasConceptScore W4284960606C2777402515 @default.
• W4284960606 hasConceptScore W4284960606C2778143017 @default.
• W4284960606 hasConceptScore W4284960606C2778579456 @default.
• W4284960606 hasConceptScore W4284960606C71924100 @default.
• W4284960606 hasConceptScore W4284960606C90924648 @default.
• W4284960606 hasIssue "1" @default.
• W4284960606 hasLocation W42849606061 @default.
• W4284960606 hasLocation W42849606062 @default.
• W4284960606 hasLocation W42849606063 @default.
• W4284960606 hasOpenAccess W4284960606 @default.
• W4284960606 hasPrimaryLocation W42849606061 @default.
• W4284960606 hasRelatedWork W2043205938 @default.
• W4284960606 hasRelatedWork W2268553463 @default.
• W4284960606 hasRelatedWork W2724296532 @default.
• W4284960606 hasRelatedWork W2750891019 @default.
• W4284960606 hasRelatedWork W2755537278 @default.
• W4284960606 hasRelatedWork W2802930083 @default.
• W4284960606 hasRelatedWork W2951301189 @default.
• W4284960606 hasRelatedWork W2968876046 @default.
• W4284960606 hasRelatedWork W3007601630 @default.
• W4284960606 hasRelatedWork W2186662246 @default.
• W4284960606 hasVolume "23" @default.
• W4284960606 isParatext "false" @default.
• W4284960606 isRetracted "false" @default.
• W4284960606 workType "article" @default.