FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4284966791> ?p ?o ?g. }

• W4284966791 endingPage "933" @default.
• W4284966791 startingPage "923" @default.
• W4284966791 abstract "The gut microbiome and its metabolism may provide crucial insight into the cause of iron deficiency anemia (IDA) in pregnant women. This study aimed to investigate the effect of the gut microbiome and its related metabolites on pregnant women with iron deficiency (ID) and IDA. Maternal cubital venous blood and stool samples were collected from healthy control pregnant women (HC, non-anemic, n=10), pregnant women with ID non-anemia (ID, n=10), and IDA (n=10). All groups were subjected to fecal metagenomics and metabolomics. The composition and function of the gut microbiome were then compared in pregnant women with ID and IDA with HC after excluding the possibility of inflammation and insufficient iron absorption capacity. Whole-genome shotgun libraries were prepared by quantifying metagenomic DNA samples with Quant-iT PicoGreen dsDNA Assay. The levels of 41 microbial species, including 21 Streptococci and ten metabolites (catechol), which could serve as siderophores, were increased. In contrast, 3 Bacteroides and six metabolites were decreased in pregnant women with IDA (p<0.05). The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis indicated that the bio-pathways, including biosynthesis of siderophore group non-ribosomal peptides (p<0.01), ABC transporters (p<0.05) and membrane transport of the gut microbiota (p<0.01) in IDA patients were expressed differently compared with HC. Correlation analysis also indicates that these increased bacteria formed strong co-occurring relationships with metabolites in the occurrence and development of IDA in pregnant women. The current study identified that streptococci and catechol (fecal metabolite) were significantly increased in pregnant women with IDA. Therefore, adjusting the intestinal homeostasis using long-term living and eating habits on oral Streptococcus in pregnant women with IDA before iron supplementation may be more conducive to iron supplementation, thus providing novel therapies for IDA." @default.
• W4284966791 created "2022-07-10" @default.
• W4284966791 creator A5005244586 @default.
• W4284966791 creator A5018638802 @default.
• W4284966791 creator A5027584765 @default.
• W4284966791 creator A5035103401 @default.
• W4284966791 creator A5055605690 @default.
• W4284966791 creator A5070726055 @default.
• W4284966791 creator A5084203107 @default.
• W4284966791 date "2022-10-23" @default.
• W4284966791 modified "2023-09-27" @default.
• W4284966791 title "Altered fecal microbial and metabolic profile reveals potential mechanisms underlying iron deficiency anemia in pregnant women in China" @default.
• W4284966791 cites W1753158170 @default.
• W4284966791 cites W1966603801 @default.
• W4284966791 cites W1969684615 @default.
• W4284966791 cites W1981407334 @default.
• W4284966791 cites W1983274646 @default.
• W4284966791 cites W1986838662 @default.
• W4284966791 cites W1993681714 @default.
• W4284966791 cites W2014138367 @default.
• W4284966791 cites W2041606982 @default.
• W4284966791 cites W2052545972 @default.
• W4284966791 cites W2078190754 @default.
• W4284966791 cites W2089643339 @default.
• W4284966791 cites W2099143902 @default.
• W4284966791 cites W2139319298 @default.
• W4284966791 cites W2144797792 @default.
• W4284966791 cites W2163158908 @default.
• W4284966791 cites W2305506207 @default.
• W4284966791 cites W2397262069 @default.
• W4284966791 cites W2555335370 @default.
• W4284966791 cites W2559952413 @default.
• W4284966791 cites W2578332244 @default.
• W4284966791 cites W2612887150 @default.
• W4284966791 cites W2614587835 @default.
• W4284966791 cites W2734548013 @default.
• W4284966791 cites W2883296821 @default.
• W4284966791 cites W2899671176 @default.
• W4284966791 cites W2900783270 @default.
• W4284966791 cites W2909151085 @default.
• W4284966791 cites W2938740549 @default.
• W4284966791 cites W2953760796 @default.
• W4284966791 cites W2970893919 @default.
• W4284966791 cites W2982784059 @default.
• W4284966791 cites W2983262756 @default.
• W4284966791 cites W2985003213 @default.
• W4284966791 cites W2986330148 @default.
• W4284966791 cites W2990378266 @default.
• W4284966791 cites W3129943882 @default.
• W4284966791 doi "https://doi.org/10.17305/bjbms.2022.7091" @default.
• W4284966791 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35803345" @default.
• W4284966791 hasPublicationYear "2022" @default.
• W4284966791 type Work @default.
• W4284966791 citedByCount "4" @default.
• W4284966791 countsByYear W42849667912023 @default.
• W4284966791 crossrefType "journal-article" @default.
• W4284966791 hasAuthorship W4284966791A5005244586 @default.
• W4284966791 hasAuthorship W4284966791A5018638802 @default.
• W4284966791 hasAuthorship W4284966791A5027584765 @default.
• W4284966791 hasAuthorship W4284966791A5035103401 @default.
• W4284966791 hasAuthorship W4284966791A5055605690 @default.
• W4284966791 hasAuthorship W4284966791A5070726055 @default.
• W4284966791 hasAuthorship W4284966791A5084203107 @default.
• W4284966791 hasBestOaLocation W42849667911 @default.
• W4284966791 hasConcept C104317684 @default.
• W4284966791 hasConcept C108319773 @default.
• W4284966791 hasConcept C126322002 @default.
• W4284966791 hasConcept C143121216 @default.
• W4284966791 hasConcept C150194340 @default.
• W4284966791 hasConcept C15151743 @default.
• W4284966791 hasConcept C152724338 @default.
• W4284966791 hasConcept C162317418 @default.
• W4284966791 hasConcept C203014093 @default.
• W4284966791 hasConcept C21565614 @default.
• W4284966791 hasConcept C2778168646 @default.
• W4284966791 hasConcept C2778248108 @default.
• W4284966791 hasConcept C2780206646 @default.
• W4284966791 hasConcept C2780305828 @default.
• W4284966791 hasConcept C42407357 @default.
• W4284966791 hasConcept C523546767 @default.
• W4284966791 hasConcept C539455810 @default.
• W4284966791 hasConcept C54355233 @default.
• W4284966791 hasConcept C55493867 @default.
• W4284966791 hasConcept C60644358 @default.
• W4284966791 hasConcept C61716771 @default.
• W4284966791 hasConcept C71924100 @default.
• W4284966791 hasConcept C86803240 @default.
• W4284966791 hasConcept C89423630 @default.
• W4284966791 hasConceptScore W4284966791C104317684 @default.
• W4284966791 hasConceptScore W4284966791C108319773 @default.
• W4284966791 hasConceptScore W4284966791C126322002 @default.
• W4284966791 hasConceptScore W4284966791C143121216 @default.
• W4284966791 hasConceptScore W4284966791C150194340 @default.
• W4284966791 hasConceptScore W4284966791C15151743 @default.
• W4284966791 hasConceptScore W4284966791C152724338 @default.
• W4284966791 hasConceptScore W4284966791C162317418 @default.
• W4284966791 hasConceptScore W4284966791C203014093 @default.
• W4284966791 hasConceptScore W4284966791C21565614 @default.

• next