Matches in SemOpenAlex for { <https://semopenalex.org/work/W4284988052> ?p ?o ?g. }
- W4284988052 endingPage "110428" @default.
- W4284988052 startingPage "110428" @default.
- W4284988052 abstract "Long noncoding RNAs (lncRNAs) can mediate the biological processes during tumorigenesis which may be affected by tumor associated macrophages (TAMs). Hence, we aim to identify the functionality of LINC00702 in regulation of bladder cancer cells and M2-TAMs.After induction of M2-TAMs from THP-1 monocyte, we evaluated effects of LINC00702 on bladder cancer cells and M2-TAMs, which were validated in a xenograft tumor mouse model.Low LINC00702 expression was determined in bladder cancer tissues. LINC00702 could promote DUSP1 transcription by recruiting JUND to its promoter. Ectopic LINC00702 expression suppressed the bladder cancer cell proliferation and secretion of inflammatory cytokines by M2-TAMs through up-regulation of DUSP1. The anti-tumor activity of LINC00702 was ultimately validated in vivo.LINC00702 promoted DUSP1 by recruiting JUND to inhibit the proliferation of bladder cancer cells and the secretion of inflammatory factors, thus modulating bladder cancer inflammatory microenvironment." @default.
- W4284988052 created "2022-07-11" @default.
- W4284988052 creator A5017230050 @default.
- W4284988052 creator A5026961184 @default.
- W4284988052 creator A5035545488 @default.
- W4284988052 creator A5038390604 @default.
- W4284988052 creator A5067156117 @default.
- W4284988052 creator A5081821056 @default.
- W4284988052 date "2022-07-01" @default.
- W4284988052 modified "2023-10-14" @default.
- W4284988052 title "LINC00702-mediated DUSP1 transcription in the prevention of bladder cancer progression: Implications in cancer cell proliferation and tumor inflammatory microenvironment" @default.
- W4284988052 cites W1572827793 @default.
- W4284988052 cites W1976119535 @default.
- W4284988052 cites W1981712836 @default.
- W4284988052 cites W1987216226 @default.
- W4284988052 cites W2049491375 @default.
- W4284988052 cites W2075995473 @default.
- W4284988052 cites W2105935489 @default.
- W4284988052 cites W2341032293 @default.
- W4284988052 cites W2343465102 @default.
- W4284988052 cites W2402586856 @default.
- W4284988052 cites W2462649057 @default.
- W4284988052 cites W2502698579 @default.
- W4284988052 cites W2541478996 @default.
- W4284988052 cites W2605830629 @default.
- W4284988052 cites W2615301036 @default.
- W4284988052 cites W2741541139 @default.
- W4284988052 cites W2766047822 @default.
- W4284988052 cites W2889646458 @default.
- W4284988052 cites W2890715893 @default.
- W4284988052 cites W2894021423 @default.
- W4284988052 cites W2902512730 @default.
- W4284988052 cites W2904889333 @default.
- W4284988052 cites W2916183155 @default.
- W4284988052 cites W2920657619 @default.
- W4284988052 cites W2921362540 @default.
- W4284988052 cites W2937107674 @default.
- W4284988052 cites W2946679053 @default.
- W4284988052 cites W2990414011 @default.
- W4284988052 cites W3006614516 @default.
- W4284988052 cites W3008550537 @default.
- W4284988052 cites W3017116665 @default.
- W4284988052 cites W3019739222 @default.
- W4284988052 cites W3081909970 @default.
- W4284988052 cites W3120089253 @default.
- W4284988052 doi "https://doi.org/10.1016/j.ygeno.2022.110428" @default.
- W4284988052 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35809838" @default.
- W4284988052 hasPublicationYear "2022" @default.
- W4284988052 type Work @default.
- W4284988052 citedByCount "6" @default.
- W4284988052 countsByYear W42849880522023 @default.
- W4284988052 crossrefType "journal-article" @default.
- W4284988052 hasAuthorship W4284988052A5017230050 @default.
- W4284988052 hasAuthorship W4284988052A5026961184 @default.
- W4284988052 hasAuthorship W4284988052A5035545488 @default.
- W4284988052 hasAuthorship W4284988052A5038390604 @default.
- W4284988052 hasAuthorship W4284988052A5067156117 @default.
- W4284988052 hasAuthorship W4284988052A5081821056 @default.
- W4284988052 hasBestOaLocation W42849880521 @default.
- W4284988052 hasConcept C104317684 @default.
- W4284988052 hasConcept C121608353 @default.
- W4284988052 hasConcept C203014093 @default.
- W4284988052 hasConcept C2776107976 @default.
- W4284988052 hasConcept C2776914184 @default.
- W4284988052 hasConcept C2780352672 @default.
- W4284988052 hasConcept C3020616263 @default.
- W4284988052 hasConcept C502942594 @default.
- W4284988052 hasConcept C54355233 @default.
- W4284988052 hasConcept C55493867 @default.
- W4284988052 hasConcept C555283112 @default.
- W4284988052 hasConcept C62112901 @default.
- W4284988052 hasConcept C81885089 @default.
- W4284988052 hasConcept C86339819 @default.
- W4284988052 hasConcept C86803240 @default.
- W4284988052 hasConcept C96232424 @default.
- W4284988052 hasConcept C97037327 @default.
- W4284988052 hasConceptScore W4284988052C104317684 @default.
- W4284988052 hasConceptScore W4284988052C121608353 @default.
- W4284988052 hasConceptScore W4284988052C203014093 @default.
- W4284988052 hasConceptScore W4284988052C2776107976 @default.
- W4284988052 hasConceptScore W4284988052C2776914184 @default.
- W4284988052 hasConceptScore W4284988052C2780352672 @default.
- W4284988052 hasConceptScore W4284988052C3020616263 @default.
- W4284988052 hasConceptScore W4284988052C502942594 @default.
- W4284988052 hasConceptScore W4284988052C54355233 @default.
- W4284988052 hasConceptScore W4284988052C55493867 @default.
- W4284988052 hasConceptScore W4284988052C555283112 @default.
- W4284988052 hasConceptScore W4284988052C62112901 @default.
- W4284988052 hasConceptScore W4284988052C81885089 @default.
- W4284988052 hasConceptScore W4284988052C86339819 @default.
- W4284988052 hasConceptScore W4284988052C86803240 @default.
- W4284988052 hasConceptScore W4284988052C96232424 @default.
- W4284988052 hasConceptScore W4284988052C97037327 @default.
- W4284988052 hasIssue "4" @default.
- W4284988052 hasLocation W42849880521 @default.
- W4284988052 hasLocation W42849880522 @default.
- W4284988052 hasOpenAccess W4284988052 @default.
- W4284988052 hasPrimaryLocation W42849880521 @default.