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- W4284993313 abstract "In this chapter, Rhesus (Rh) and Landsteiner-Wiener (LW) antigens are incorporated together based on a historic serologic connection and evidence that they are physically associated within the red cell membrane. The Rh system is second only to the ABO system in importance in transfusion medicine because Rh antigens, especially D, are highly immunogenic, and antibodies to these antigens cause hemolytic disease of the fetus and newborn and hemolytic transfusion reactions. The Rh proteins exist in the red cell membrane as complexes with several other proteins, with Rh and Rh-associated glycoprotein serving as the core of the complex. Genotyping is important in the prenatal setting to determine whether the fetus has inherited the paternal antigen to which the mother has a clinically significant antibody. The LW antigens are the original so-called “Rhesus” antigens shared by humans and the rhesus monkey." @default.
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- W4284993313 date "2022-07-10" @default.
- W4284993313 modified "2023-09-27" @default.
- W4284993313 title "Rh and LW blood group antigens" @default.
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- W4284993313 doi "https://doi.org/10.1002/9781119719809.ch10" @default.
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