FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285005681> ?p ?o ?g. }

• W4285005681 endingPage "1949" @default.
• W4285005681 startingPage "1942" @default.
• W4285005681 abstract "Diet and genetic predisposition to adiposity are independent predictors of body composition, yet few cohort studies have examined the association between overall diet quality indices, genetic risk and body composition. This study examined the prospective association of three diet quality indices and a polygenic risk score (PRS) with trunk fat mass, total fat mass, lean mass and bone mineral content.Adults from UK Biobank cohort were included. Dietary intake was assessed using the Oxford WebQ and three diet quality indices calculated: Recommended Food Score (RFS); Mediterranean Diet Score (MDS); Healthy Diet Indicator (HDI). Bioimpedance data were available for trunk fat, total fat and lean mass (kg). Trunk fat mass (kg), total fat mass (kg) and lean mass (kg) were assessed using bioelectrical impedance (BIA) in 17,478 adults. Bone mineral content (g) was available from dual energy x-ray absorptiometry (DXA) scans in 11,887 participants. Linear regression analyses, adjusted for demographic and lifestyle confounders, were used to estimate prospective associations between each diet quality index and body composition outcomes. A PRS created from 97 adiposity-related single nucleotide polymorphisms was used to examine interaction effects.A total of 17,478 adults (M = 55.9, SD 7.5 years) were followed up for up to 10 years. RFS, HDI and MDS were inversely associated with trunk fat (RFS: B -0.29; 95% CI: -0.33, -0.25; HDI: -0.23; -0.27, -0.19; MDS: -0.22; -0.26, -0.18), total fat (RFS: B -0.49; 95% CI: -0.56, -0.42; HDI: -0.38; -0.45, -0.32; MDS: -0.38; -0.44, -0.32) and lean (RFS: B -0.10; 95% CI: -0.14, -0.06; HDI: -0.07; -0.11, -0.03; MDS: -0.07; -0.11, -0.04) mass. Diet quality was positively associated with bone mineral content (RFS: B 8.23; 95% CI: 2.14, 14.3; HDI: 6.77; 1.00, 12.5). There was evidence of non-linear associations between diet quality (RFS and HDI only) and trunk fat (p < 0.01) and total fat mass (p < 0.05). There was limited evidence PRS was associated with body composition, with interaction effects of PRS and HDI (p-interaction = 0.039) and MDS (p-interaction = 0.031) on total fat mass.Higher diet quality was associated with lower trunk fat, total fat and lean mass, regardless of the diet quality index examined (RFS, HDI or MDS), while higher diet quality (RFS and HDI only) was associated with higher bone mineral content. The benefit of higher diet quality on reducing total fat mass was most evident in individuals with higher generic risk of adiposity. These findings underscore the importance of a high-quality diet for maintaining optimal body composition, particularly in individuals with genetic pre-disposition to adiposity." @default.
• W4285005681 created "2022-07-12" @default.
• W4285005681 creator A5011918902 @default.
• W4285005681 creator A5013311417 @default.
• W4285005681 creator A5015614820 @default.
• W4285005681 creator A5015959631 @default.
• W4285005681 creator A5030050502 @default.
• W4285005681 creator A5040947655 @default.
• W4285005681 creator A5043144062 @default.
• W4285005681 creator A5053003430 @default.
• W4285005681 creator A5083221850 @default.
• W4285005681 date "2022-09-01" @default.
• W4285005681 modified "2023-09-29" @default.
• W4285005681 title "Associations between three diet quality indices, genetic risk and body composition: A prospective cohort study" @default.
• W4285005681 cites W1978710215 @default.
• W4285005681 cites W1987608603 @default.
• W4285005681 cites W2014332852 @default.
• W4285005681 cites W2019141360 @default.
• W4285005681 cites W2032068298 @default.
• W4285005681 cites W2060426034 @default.
• W4285005681 cites W2079887487 @default.
• W4285005681 cites W2082704080 @default.
• W4285005681 cites W2094332493 @default.
• W4285005681 cites W2108176440 @default.
• W4285005681 cites W2153676698 @default.
• W4285005681 cites W2171129594 @default.
• W4285005681 cites W2402987138 @default.
• W4285005681 cites W2527260961 @default.
• W4285005681 cites W2572585116 @default.
• W4285005681 cites W2620406790 @default.
• W4285005681 cites W2790447956 @default.
• W4285005681 cites W2810529814 @default.
• W4285005681 cites W2810806985 @default.
• W4285005681 cites W2892573813 @default.
• W4285005681 cites W2896678274 @default.
• W4285005681 cites W2898518163 @default.
• W4285005681 cites W2912602217 @default.
• W4285005681 cites W2927029344 @default.
• W4285005681 cites W2949057804 @default.
• W4285005681 cites W2963525085 @default.
• W4285005681 cites W2965417313 @default.
• W4285005681 cites W3001377667 @default.
• W4285005681 cites W3018859837 @default.
• W4285005681 cites W3032464132 @default.
• W4285005681 cites W3048564759 @default.
• W4285005681 cites W3092886169 @default.
• W4285005681 cites W3118558188 @default.
• W4285005681 cites W3150769455 @default.
• W4285005681 cites W3215464165 @default.
• W4285005681 cites W4293254419 @default.
• W4285005681 doi "https://doi.org/10.1016/j.clnu.2022.07.005" @default.
• W4285005681 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35947896" @default.
• W4285005681 hasPublicationYear "2022" @default.
• W4285005681 type Work @default.
• W4285005681 citedByCount "2" @default.
• W4285005681 countsByYear W42850056812023 @default.
• W4285005681 crossrefType "journal-article" @default.
• W4285005681 hasAuthorship W4285005681A5011918902 @default.
• W4285005681 hasAuthorship W4285005681A5013311417 @default.
• W4285005681 hasAuthorship W4285005681A5015614820 @default.
• W4285005681 hasAuthorship W4285005681A5015959631 @default.
• W4285005681 hasAuthorship W4285005681A5030050502 @default.
• W4285005681 hasAuthorship W4285005681A5040947655 @default.
• W4285005681 hasAuthorship W4285005681A5043144062 @default.
• W4285005681 hasAuthorship W4285005681A5053003430 @default.
• W4285005681 hasAuthorship W4285005681A5083221850 @default.
• W4285005681 hasConcept C120863210 @default.
• W4285005681 hasConcept C126322002 @default.
• W4285005681 hasConcept C147583825 @default.
• W4285005681 hasConcept C188816634 @default.
• W4285005681 hasConcept C18903297 @default.
• W4285005681 hasConcept C201903717 @default.
• W4285005681 hasConcept C2780221984 @default.
• W4285005681 hasConcept C2781197403 @default.
• W4285005681 hasConcept C33872192 @default.
• W4285005681 hasConcept C42407357 @default.
• W4285005681 hasConcept C71924100 @default.
• W4285005681 hasConcept C72563966 @default.
• W4285005681 hasConcept C77350462 @default.
• W4285005681 hasConcept C86803240 @default.
• W4285005681 hasConceptScore W4285005681C120863210 @default.
• W4285005681 hasConceptScore W4285005681C126322002 @default.
• W4285005681 hasConceptScore W4285005681C147583825 @default.
• W4285005681 hasConceptScore W4285005681C188816634 @default.
• W4285005681 hasConceptScore W4285005681C18903297 @default.
• W4285005681 hasConceptScore W4285005681C201903717 @default.
• W4285005681 hasConceptScore W4285005681C2780221984 @default.
• W4285005681 hasConceptScore W4285005681C2781197403 @default.
• W4285005681 hasConceptScore W4285005681C33872192 @default.
• W4285005681 hasConceptScore W4285005681C42407357 @default.
• W4285005681 hasConceptScore W4285005681C71924100 @default.
• W4285005681 hasConceptScore W4285005681C72563966 @default.
• W4285005681 hasConceptScore W4285005681C77350462 @default.
• W4285005681 hasConceptScore W4285005681C86803240 @default.
• W4285005681 hasFunder F4320320970 @default.
• W4285005681 hasFunder F4320334705 @default.
• W4285005681 hasIssue "9" @default.
• W4285005681 hasLocation W42850056811 @default.

• next