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- W4285008076 abstract "Abstract To optimize the extraction process and activity detection of total polyphenols from Toona sinensis . A Box–Behnken design of response surface methodology was employed to further optimize ultrasonic-assisted extraction (UAE) conditions for T. sinensis stems total polyphenols ( TSTP ). The results showed that optimized extraction conditions were ultrasonic power of 200 W, liquid-solid ratio of 50 mL/g, ultrasonic temperature of 60°C and ultrasonic time of 22 min. Under these conditions, the mean experimental value of extraction yield (8.13%) was achieved, which was about 49.44% higher than that of distilled water leaching extraction. As compared to TSTP, TSTP after purification ( TSPTP ) had higher purity of 57.70%, which was nearly 45.33% higher than that of TSTP (12.37%). TSPTP had higher α -glucosidase and α -amylase inhibitory activities as well as DPPH· and ABTS· + scavenging activities with an IC 50 value of 0.201, 0.041, 0.27 and 0.07 mg/mL. TSPTP from T. sinensis could be considered as multifunctional bioactive ingredients to be used in anti-hyperglycemic pharmaceutical formulation and antioxidant." @default.
- W4285008076 created "2022-07-12" @default.
- W4285008076 creator A5058537981 @default.
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- W4285008076 date "2022-07-11" @default.
- W4285008076 modified "2023-09-27" @default.
- W4285008076 title "Optimization of ultrasonic assisted extraction and biological activity of total polyphenols from Toona sinensis using response surface methodology" @default.
- W4285008076 doi "https://doi.org/10.21203/rs.3.rs-1797921/v1" @default.
- W4285008076 hasPublicationYear "2022" @default.
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