FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285010018> ?p ?o ?g. }

• W4285010018 endingPage "988" @default.
• W4285010018 startingPage "988" @default.
• W4285010018 abstract "(1) Background: L-carnosine (β-alanyl-L-histidine), a natural dipeptide, exists at relatively high concentrations in skeletal muscles, and has been shown to protect cells from adverse conditions due to its antioxidant, anti-aging, anti-glycation, and buffering properties. Satellite cells (SCs), residing on the myofiber surface, are crucial for muscle post-growth and regeneration. However, the effects of L-carnosine on muscle development of pigs in vivo, on proliferation and growth of SCs in vitro, and the relationship between SCs and muscle development have not yet been investigated. (2) Methods: The objective of this study was to assess the effect of dietary L-carnosine on growth performance and longissimus dorsi muscle development of pigs in vivo, and to elaborate its molecular mechanisms in vitro using L-carnosine-treated SCs. (3) Results: It was shown that L-carnosine supplementation (0.2 and 2 mM) increased (p < 0.05) SC proliferation and cell percentage in the synthesis (S) phase and decreased cell percentage in the resting (G0)/first gap (G1)/phase. Moreover, average daily gain (ADG) of pigs fed diets containing 0.1% of L-carnosine was higher (p < 0.05) than that of pigs fed diets without L-carnosine, and the longissimus dorsi muscle weight of pigs assigned to the L-carnosine treatments was 7.95% higher compared to control pigs. Both in the longissimus dorsi muscle and cultured SCs of pigs, the Akt/mTOR/S6K signaling pathway was activated (p < 0.05), suggesting that L-carnosine improved muscle growth and SC proliferation of pigs. (4) Conclusions: Considering the important role of SCs in post-natal muscle growth, there is evidence that L-carnosine may improve muscle growth of pigs through promoting SC proliferation via activating the Akt/mTOR/S6K signaling pathway." @default.
• W4285010018 created "2022-07-12" @default.
• W4285010018 creator A5003721215 @default.
• W4285010018 creator A5013652689 @default.
• W4285010018 creator A5015052154 @default.
• W4285010018 creator A5023494082 @default.
• W4285010018 creator A5024112072 @default.
• W4285010018 creator A5024591012 @default.
• W4285010018 creator A5030766421 @default.
• W4285010018 creator A5033234173 @default.
• W4285010018 creator A5049952527 @default.
• W4285010018 creator A5054452844 @default.
• W4285010018 creator A5085952344 @default.
• W4285010018 date "2022-07-08" @default.
• W4285010018 modified "2023-10-18" @default.
• W4285010018 title "Improved Satellite Cell Proliferation Induced by L-Carnosine Benefits Muscle Growth of Pigs in Part through Activation of the Akt/mTOR/S6K Signaling Pathway" @default.
• W4285010018 cites W1580756874 @default.
• W4285010018 cites W1586159393 @default.
• W4285010018 cites W1850169595 @default.
• W4285010018 cites W2011963221 @default.
• W4285010018 cites W2016908596 @default.
• W4285010018 cites W2023630283 @default.
• W4285010018 cites W2025957803 @default.
• W4285010018 cites W2027792171 @default.
• W4285010018 cites W2031527929 @default.
• W4285010018 cites W2048414592 @default.
• W4285010018 cites W2051529841 @default.
• W4285010018 cites W2082306065 @default.
• W4285010018 cites W2092915424 @default.
• W4285010018 cites W2094222260 @default.
• W4285010018 cites W2095675199 @default.
• W4285010018 cites W2096329353 @default.
• W4285010018 cites W2097777266 @default.
• W4285010018 cites W2101428185 @default.
• W4285010018 cites W2126166752 @default.
• W4285010018 cites W2127063807 @default.
• W4285010018 cites W2134769353 @default.
• W4285010018 cites W2145040756 @default.
• W4285010018 cites W2152128755 @default.
• W4285010018 cites W2157760261 @default.
• W4285010018 cites W2158769524 @default.
• W4285010018 cites W2206269655 @default.
• W4285010018 cites W2223742570 @default.
• W4285010018 cites W2291414087 @default.
• W4285010018 cites W2346705222 @default.
• W4285010018 cites W2582131316 @default.
• W4285010018 cites W2593816418 @default.
• W4285010018 cites W281681086 @default.
• W4285010018 cites W2913465781 @default.
• W4285010018 cites W2990653252 @default.
• W4285010018 cites W3006425357 @default.
• W4285010018 cites W3016210710 @default.
• W4285010018 cites W3019525637 @default.
• W4285010018 cites W3087204040 @default.
• W4285010018 cites W3094201421 @default.
• W4285010018 cites W3101475529 @default.
• W4285010018 cites W3109527448 @default.
• W4285010018 cites W3196394008 @default.
• W4285010018 cites W32359538 @default.
• W4285010018 cites W609760011 @default.
• W4285010018 doi "https://doi.org/10.3390/agriculture12070988" @default.
• W4285010018 hasPublicationYear "2022" @default.
• W4285010018 type Work @default.
• W4285010018 citedByCount "3" @default.
• W4285010018 countsByYear W42850100182023 @default.
• W4285010018 crossrefType "journal-article" @default.
• W4285010018 hasAuthorship W4285010018A5003721215 @default.
• W4285010018 hasAuthorship W4285010018A5013652689 @default.
• W4285010018 hasAuthorship W4285010018A5015052154 @default.
• W4285010018 hasAuthorship W4285010018A5023494082 @default.
• W4285010018 hasAuthorship W4285010018A5024112072 @default.
• W4285010018 hasAuthorship W4285010018A5024591012 @default.
• W4285010018 hasAuthorship W4285010018A5030766421 @default.
• W4285010018 hasAuthorship W4285010018A5033234173 @default.
• W4285010018 hasAuthorship W4285010018A5049952527 @default.
• W4285010018 hasAuthorship W4285010018A5054452844 @default.
• W4285010018 hasAuthorship W4285010018A5085952344 @default.
• W4285010018 hasBestOaLocation W42850100181 @default.
• W4285010018 hasConcept C104202773 @default.
• W4285010018 hasConcept C126322002 @default.
• W4285010018 hasConcept C134018914 @default.
• W4285010018 hasConcept C150903083 @default.
• W4285010018 hasConcept C16685009 @default.
• W4285010018 hasConcept C185592680 @default.
• W4285010018 hasConcept C207001950 @default.
• W4285010018 hasConcept C207200792 @default.
• W4285010018 hasConcept C2779959927 @default.
• W4285010018 hasConcept C2780687331 @default.
• W4285010018 hasConcept C55493867 @default.
• W4285010018 hasConcept C62112901 @default.
• W4285010018 hasConcept C62478195 @default.
• W4285010018 hasConcept C71924100 @default.
• W4285010018 hasConcept C86554907 @default.
• W4285010018 hasConcept C86803240 @default.
• W4285010018 hasConceptScore W4285010018C104202773 @default.
• W4285010018 hasConceptScore W4285010018C126322002 @default.
• W4285010018 hasConceptScore W4285010018C134018914 @default.
• W4285010018 hasConceptScore W4285010018C150903083 @default.

• next