Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285013403> ?p ?o ?g. }
- W4285013403 abstract "Autism spectrum disorder (ASD) is a highly heritable, complex disorder in which rare variants contribute significantly to disease risk. Although many genes have been associated with ASD, there have been few genetic studies of ASD in the Japanese population. In whole exomes from a Japanese ASD sample of 309 cases and 299 controls, rare variants were associated with ASD within specific neurodevelopmental gene sets, including highly constrained genes, fragile X mental retardation protein target genes, and genes involved in synaptic function, with the strongest enrichment in trans-synaptic signaling (p = 4.4 × 10-4, Q-value = 0.06). In particular, we strengthen the evidence regarding the role of ABCA13, a synaptic function-related gene, in Japanese ASD. The overall results of this case-control exome study showed that rare variants related to synaptic function are associated with ASD susceptibility in the Japanese population." @default.
- W4285013403 created "2022-07-12" @default.
- W4285013403 creator A5001942683 @default.
- W4285013403 creator A5010635227 @default.
- W4285013403 creator A5018784643 @default.
- W4285013403 creator A5018899574 @default.
- W4285013403 creator A5026728831 @default.
- W4285013403 creator A5029984259 @default.
- W4285013403 creator A5037444292 @default.
- W4285013403 creator A5038601716 @default.
- W4285013403 creator A5038990573 @default.
- W4285013403 creator A5041453760 @default.
- W4285013403 creator A5042278938 @default.
- W4285013403 creator A5053278942 @default.
- W4285013403 creator A5053317374 @default.
- W4285013403 creator A5055063676 @default.
- W4285013403 creator A5067909749 @default.
- W4285013403 creator A5071402049 @default.
- W4285013403 creator A5074008074 @default.
- W4285013403 creator A5085467135 @default.
- W4285013403 creator A5086152137 @default.
- W4285013403 creator A5088728907 @default.
- W4285013403 date "2022-07-11" @default.
- W4285013403 modified "2023-10-14" @default.
- W4285013403 title "Exome sequencing analysis of Japanese autism spectrum disorder case-control sample supports an increased burden of synaptic function-related genes" @default.
- W4285013403 cites W1168911763 @default.
- W4285013403 cites W1546528060 @default.
- W4285013403 cites W1919257374 @default.
- W4285013403 cites W1963879704 @default.
- W4285013403 cites W1975228824 @default.
- W4285013403 cites W1980309199 @default.
- W4285013403 cites W1980740976 @default.
- W4285013403 cites W1984068087 @default.
- W4285013403 cites W1993323334 @default.
- W4285013403 cites W2008627757 @default.
- W4285013403 cites W2009742334 @default.
- W4285013403 cites W2024642024 @default.
- W4285013403 cites W2044186109 @default.
- W4285013403 cites W2052326665 @default.
- W4285013403 cites W2055655674 @default.
- W4285013403 cites W2059145105 @default.
- W4285013403 cites W2063786220 @default.
- W4285013403 cites W2076359272 @default.
- W4285013403 cites W2077418754 @default.
- W4285013403 cites W2082023836 @default.
- W4285013403 cites W2092825250 @default.
- W4285013403 cites W2100254283 @default.
- W4285013403 cites W2102213696 @default.
- W4285013403 cites W2108994842 @default.
- W4285013403 cites W2118477852 @default.
- W4285013403 cites W2166349141 @default.
- W4285013403 cites W2167695374 @default.
- W4285013403 cites W2170685496 @default.
- W4285013403 cites W2176146180 @default.
- W4285013403 cites W2256016639 @default.
- W4285013403 cites W2303475965 @default.
- W4285013403 cites W2522446187 @default.
- W4285013403 cites W2529263373 @default.
- W4285013403 cites W2757581422 @default.
- W4285013403 cites W2765570630 @default.
- W4285013403 cites W2765792294 @default.
- W4285013403 cites W2783019319 @default.
- W4285013403 cites W2784031081 @default.
- W4285013403 cites W2886989735 @default.
- W4285013403 cites W2914482125 @default.
- W4285013403 cites W2923019381 @default.
- W4285013403 cites W2948949781 @default.
- W4285013403 cites W2948953603 @default.
- W4285013403 cites W2955503846 @default.
- W4285013403 cites W2971462245 @default.
- W4285013403 cites W2983765585 @default.
- W4285013403 cites W2999081868 @default.
- W4285013403 cites W3007991067 @default.
- W4285013403 cites W3046835573 @default.
- W4285013403 cites W3087082589 @default.
- W4285013403 cites W3112557112 @default.
- W4285013403 cites W3112577789 @default.
- W4285013403 cites W3113241336 @default.
- W4285013403 cites W3132435992 @default.
- W4285013403 cites W3175888462 @default.
- W4285013403 cites W3194509722 @default.
- W4285013403 doi "https://doi.org/10.1038/s41398-022-02033-6" @default.
- W4285013403 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35811316" @default.
- W4285013403 hasPublicationYear "2022" @default.
- W4285013403 type Work @default.
- W4285013403 citedByCount "2" @default.
- W4285013403 countsByYear W42850134032022 @default.
- W4285013403 crossrefType "journal-article" @default.
- W4285013403 hasAuthorship W4285013403A5001942683 @default.
- W4285013403 hasAuthorship W4285013403A5010635227 @default.
- W4285013403 hasAuthorship W4285013403A5018784643 @default.
- W4285013403 hasAuthorship W4285013403A5018899574 @default.
- W4285013403 hasAuthorship W4285013403A5026728831 @default.
- W4285013403 hasAuthorship W4285013403A5029984259 @default.
- W4285013403 hasAuthorship W4285013403A5037444292 @default.
- W4285013403 hasAuthorship W4285013403A5038601716 @default.
- W4285013403 hasAuthorship W4285013403A5038990573 @default.
- W4285013403 hasAuthorship W4285013403A5041453760 @default.
- W4285013403 hasAuthorship W4285013403A5042278938 @default.
- W4285013403 hasAuthorship W4285013403A5053278942 @default.