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- W4285015040 startingPage "3987" @default.
- W4285015040 abstract "Neonates with congenital heart disease (CHD) are at an increased risk of developing necrotizing enterocolitis (NEC), an acute inflammatory intestinal injury most commonly associated with preterm infants. The rarity of this complex disease, termed cardiac NEC, has resulted in a dearth of information on its pathophysiology. However, a higher incidence in term infants, effects on more distal regions of the intestine, and potentially a differential immune response may distinguish cardiac NEC as a distinct condition from the more common preterm, classical NEC. In this review, risk factors, differentiated from those of classical NEC, are discussed according to their potential contribution to the disease process, and a general pathogenesis is postulated for cardiac NEC. Additionally, biomarkers specific to cardiac NEC, clinical outcomes, and strategies for achieving enteral feeds are discussed. Working towards an understanding of the mechanisms underlying cardiac NEC may aid in future diagnosis of the condition and provide potential therapeutic targets." @default.
- W4285015040 created "2022-07-12" @default.
- W4285015040 creator A5001958744 @default.
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- W4285015040 creator A5040773913 @default.
- W4285015040 creator A5059746979 @default.
- W4285015040 creator A5088121978 @default.
- W4285015040 date "2022-07-09" @default.
- W4285015040 modified "2023-10-10" @default.
- W4285015040 title "Clinical Characteristics and Potential Pathogenesis of Cardiac Necrotizing Enterocolitis in Neonates with Congenital Heart Disease: A Narrative Review" @default.
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