FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285048887> ?p ?o ?g. }

• W4285048887 endingPage "11" @default.
• W4285048887 startingPage "1" @default.
• W4285048887 abstract "The objective of this study is to form a cancer stem cell index-based model to stratify HCC risk and predict survival. After screening the Tumor Genome Atlas (TCGA) of liver and normal liver tissue samples, we obtained differentially expressed genes (DEGs). We employed a weighted correlation network analysis (WGCNA) and differentially expressed genes were studied in HCC to find the modules most associated with cancer stem cells (mRNAsi). At the same time, gene ontology and Kyoto Genome Encyclopedia (KEGG) were used for functional annotation and combined with LASSO, univariate, and multivariate COX regression analyses, a prediction model of key module genes of cancer stem cells was developed. The model’s clinical efficacy was measured using the C index, calibration curve, multiindex ROC curve, and clinical decision curve. WGCNA found that black modules were most correlated with tumour stem cell index. Seven genes (CSDC2, GNA14, LGI2, MMRN1, PDE2A, SELP, and STK32B) were filtered by univariate, LASSO, and multivariate Cox regression analyses to establish the primary HCC model. The survival analysis and ROC curve in the TCGA training and validation cohort showed good performance. The independent prognostic factor of primary HCC was risk score, according to univariate and multivariate Cox regression analyses. It is found that the stem cell index model of 7 genes could predict factors independently, indicating that signatures of the stem cell will play a significant role in liver cancer survival prediction and risk stratification." @default.
• W4285048887 created "2022-07-13" @default.
• W4285048887 creator A5012083956 @default.
• W4285048887 creator A5012321817 @default.
• W4285048887 creator A5019209971 @default.
• W4285048887 creator A5052498948 @default.
• W4285048887 date "2022-06-08" @default.
• W4285048887 modified "2023-09-26" @default.
• W4285048887 title "Prognostic Value of Stem Cell Index-Related Characteristics in Primary Hepatocellular Carcinoma" @default.
• W4285048887 cites W1835730169 @default.
• W4285048887 cites W1966327575 @default.
• W4285048887 cites W2035618305 @default.
• W4285048887 cites W2056353125 @default.
• W4285048887 cites W2059207532 @default.
• W4285048887 cites W2070323020 @default.
• W4285048887 cites W2096460033 @default.
• W4285048887 cites W2099789788 @default.
• W4285048887 cites W2108900994 @default.
• W4285048887 cites W2133425503 @default.
• W4285048887 cites W2137052325 @default.
• W4285048887 cites W2141448996 @default.
• W4285048887 cites W2149199519 @default.
• W4285048887 cites W2153349010 @default.
• W4285048887 cites W2411616513 @default.
• W4285048887 cites W2755997084 @default.
• W4285048887 cites W2760980960 @default.
• W4285048887 cites W2782248232 @default.
• W4285048887 cites W2795867722 @default.
• W4285048887 cites W2796448036 @default.
• W4285048887 cites W286425085 @default.
• W4285048887 cites W2966695676 @default.
• W4285048887 cites W2982638381 @default.
• W4285048887 cites W3000080936 @default.
• W4285048887 cites W3022854879 @default.
• W4285048887 doi "https://doi.org/10.1155/2022/2672033" @default.
• W4285048887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35800238" @default.
• W4285048887 hasPublicationYear "2022" @default.
• W4285048887 type Work @default.
• W4285048887 citedByCount "3" @default.
• W4285048887 countsByYear W42850488872022 @default.
• W4285048887 countsByYear W42850488872023 @default.
• W4285048887 crossrefType "journal-article" @default.
• W4285048887 hasAuthorship W4285048887A5012083956 @default.
• W4285048887 hasAuthorship W4285048887A5012321817 @default.
• W4285048887 hasAuthorship W4285048887A5019209971 @default.
• W4285048887 hasAuthorship W4285048887A5052498948 @default.
• W4285048887 hasBestOaLocation W42850488871 @default.
• W4285048887 hasConcept C104317684 @default.
• W4285048887 hasConcept C119857082 @default.
• W4285048887 hasConcept C126322002 @default.
• W4285048887 hasConcept C136764020 @default.
• W4285048887 hasConcept C143998085 @default.
• W4285048887 hasConcept C150194340 @default.
• W4285048887 hasConcept C152724338 @default.
• W4285048887 hasConcept C161584116 @default.
• W4285048887 hasConcept C162317418 @default.
• W4285048887 hasConcept C199163554 @default.
• W4285048887 hasConcept C2778019345 @default.
• W4285048887 hasConcept C37616216 @default.
• W4285048887 hasConcept C41008148 @default.
• W4285048887 hasConcept C50382708 @default.
• W4285048887 hasConcept C54355233 @default.
• W4285048887 hasConcept C58471807 @default.
• W4285048887 hasConcept C70721500 @default.
• W4285048887 hasConcept C71924100 @default.
• W4285048887 hasConcept C86803240 @default.
• W4285048887 hasConceptScore W4285048887C104317684 @default.
• W4285048887 hasConceptScore W4285048887C119857082 @default.
• W4285048887 hasConceptScore W4285048887C126322002 @default.
• W4285048887 hasConceptScore W4285048887C136764020 @default.
• W4285048887 hasConceptScore W4285048887C143998085 @default.
• W4285048887 hasConceptScore W4285048887C150194340 @default.
• W4285048887 hasConceptScore W4285048887C152724338 @default.
• W4285048887 hasConceptScore W4285048887C161584116 @default.
• W4285048887 hasConceptScore W4285048887C162317418 @default.
• W4285048887 hasConceptScore W4285048887C199163554 @default.
• W4285048887 hasConceptScore W4285048887C2778019345 @default.
• W4285048887 hasConceptScore W4285048887C37616216 @default.
• W4285048887 hasConceptScore W4285048887C41008148 @default.
• W4285048887 hasConceptScore W4285048887C50382708 @default.
• W4285048887 hasConceptScore W4285048887C54355233 @default.
• W4285048887 hasConceptScore W4285048887C58471807 @default.
• W4285048887 hasConceptScore W4285048887C70721500 @default.
• W4285048887 hasConceptScore W4285048887C71924100 @default.
• W4285048887 hasConceptScore W4285048887C86803240 @default.
• W4285048887 hasLocation W42850488871 @default.
• W4285048887 hasLocation W42850488872 @default.
• W4285048887 hasLocation W42850488873 @default.
• W4285048887 hasOpenAccess W4285048887 @default.
• W4285048887 hasPrimaryLocation W42850488871 @default.
• W4285048887 hasRelatedWork W2568975186 @default.
• W4285048887 hasRelatedWork W3124800575 @default.
• W4285048887 hasRelatedWork W3155235623 @default.
• W4285048887 hasRelatedWork W3162455570 @default.
• W4285048887 hasRelatedWork W3188659381 @default.
• W4285048887 hasRelatedWork W3199257076 @default.
• W4285048887 hasRelatedWork W3200895526 @default.
• W4285048887 hasRelatedWork W3205250160 @default.

• next