Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285089788> ?p ?o ?g. }
- W4285089788 abstract "Abstract Cholangiocarcinoma (CHOL) is one of the most aggressive tumors worldwide and cannot be effectively treated by conventional and novel treatments, including immune checkpoint blockade therapy. The mRNA vaccine-based immunotherapeutic strategy has attracted much attention for various diseases, however, its application in CHOL is limited due to the thoughtlessness in the integration of vaccine design and patient selection. A recent study established an integrated path for identifying potent CHOL antigens for mRNA vaccine development and a precise stratification for identifying CHOL patients who can benefit from the mRNA vaccines. In spite of a promising prospect, further investigations should identify immunogenic antigens and onco-immunological characteristics of CHOL to guide the clinical application of CHOL mRNA vaccines in the future." @default.
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- W4285089788 date "2022-07-12" @default.
- W4285089788 modified "2023-10-14" @default.
- W4285089788 title "mRNA vaccine development for cholangiocarcinoma: a precise pipeline" @default.
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- W4285089788 doi "https://doi.org/10.1186/s40779-022-00399-8" @default.
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