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- W4285094064 abstract "Abstract Dendrimers are appealing scaffolds for creating carbohydrate mimics with unique multivalent cooperativity. We report here novel bola‐amphiphilic glycodendrimers bearing mannose and glucose terminals, and a hydrophobic thioacetal core responsive to reactive oxygen species. The peculiar bola‐amphiphilic feature enabled stronger binding to lectin compared to conventional amphiphiles. In addition, these dendrimers are able to target mannose receptors and glucose transporters expressed at the surface of cells, thus allowing effective and specific cellular uptake. This highlights their great promise for targeted delivery." @default.
- W4285094064 created "2022-07-14" @default.
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- W4285094064 date "2022-08-26" @default.
- W4285094064 modified "2023-09-26" @default.
- W4285094064 title "Bola‐Amphiphilic Glycodendrimers: New Carbohydrate‐Mimicking Scaffolds to Target Carbohydrate‐Binding Proteins" @default.
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- W4285094064 doi "https://doi.org/10.1002/chem.202201400" @default.
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