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• W4285100479 abstract "ABO不適合生体腎移植（ABOi-LKT）において抗A/B抗体価を測定することは治療選択および予後評価に有用である．抗A/B抗体価の測定は試験管法（TT）で行われるが，測定者間差や施設間差が問題とされている．カラム遠心凝集法による抗体価自動分析法（auto-CAT）は試験管法の欠点を補う方法として期待されている．我々は，ABOi-LKT症例を対象に，auto-CATとTTを用いて抗A/B抗体価を測定し，auto-CATの有用性を多施設共同研究で検討した．共同研究4施設でABOi-LKT35症例，合計111サンプルの測定を行った．2法の相関係数は0.9以上であり，一致率および臨床的許容一致率は60.4%，88.3%であった．Auto-CATは，周術期の治療などの影響を受けず，IgG抗体価は時系列変化でみるとTTとauto-CATで平行して変化していた．Auto-CATはIgG抗A/B抗体価測定においてTTと同等であり，ABOi-LKT症例の抗A/B抗体価測定に適している．" @default.
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• W4285100479 date "2022-06-24" @default.
• W4285100479 modified "2023-10-07" @default.
• W4285100479 title "FEASIBILITY OF THE AUTOMATED COLUMN AGGLUTINATION TECHNIQUE FOR TITRATION OF ANTI-A/B ANTIBODIES IN ABO-INCOMPATIBLE LIVING KIDNEY TRANSPLANTATION" @default.
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• W4285100479 doi "https://doi.org/10.3925/jjtc.68.449" @default.
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