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- W4285100692 abstract "Objective: The emergence of multi-drug-resistant pathogens on antimicrobials in current use has made it necessary to search for alternative treatment strategies. Plant essential oils are considered as alternative antimicrobials in the treatment of diseases because they are non-toxic, cost-effective and accessible. This study aimed to evaluate the antibacterial and antibiofilm effect and anti-quarum sensing (QS) properties of Cinnamomun verum leaf essential oil on Pseudomonas aeruginosa and Acinetobacter baumannii. Materials and Methods: In the study, Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of EO on P. aeruginosa and A. baumannii were determined. The microdilution method was used to determine the minimum inhibitory concentrations (MICs). The chemical content of C. verum EO was determined using Gas Chromatography-Mass Spectrometry (GC-MS). Results: C. verum EO showed MIC and MBC at 0.5 and 1.0 mg/mL versus strains tested. It was determined that C. verum EO showed high anti-QS activity at a concentration of 2 mg/mL. According to GC-MS results, cinnamaldehyde was found to be the most abundant compound in C. verum EO. Conclusion: C. verum EO has potential to be used against infections caused by bacterial biofilms. Studies on the anti-QS activity of C. verum EOs are limited, and the anti-QS activity on pathogenic microorganisms should be investigated in this area." @default.
- W4285100692 created "2022-07-14" @default.
- W4285100692 creator A5012641182 @default.
- W4285100692 date "2022-06-20" @default.
- W4285100692 modified "2023-09-27" @default.
- W4285100692 title "Anti-quarum Sensing Activity of Cinnamomum verum Essential Oil with Antibacterial and Antibiofilm Effect on Pseudomonas aeruginosa and Acinetobacter baumannii" @default.
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- W4285100692 doi "https://doi.org/10.53424/balikesirsbd.1071396" @default.
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